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51.
Aim: Conventional soybean lipid emulsions contain no docosahexaenoic acid (DHA) or arachidonic acid (AA). We investigated the relationship between blood DHA and AA status in 27 very‐low‐birth‐weight (VLBW) infants with or without parenteral lipid emulsion. Methods: Sixteen infants received parenteral lipid emulsion, and 11 infants were control group. The fatty acid composition of the erythrocyte membrane was analysed at birth and at 2 weeks of age. Results: No significant difference in AA levels was observed in the lipid emulsion group between the two time points, whereas the AA levels at 2 weeks were significantly lower than at birth in the control group. The DHA levels in both groups at 2 weeks were significantly lower than at birth, but no group differences were observed at both time points. Conclusion: The use of parenteral soybean oil lipid emulsions in VLBW infants in the postnatal period may prevent the decline in the AA level but does not appear to influence the DHA level.  相似文献   
52.
The specificity and dose dependence of the synergistic effects of soybean intake with iodine deficiency on the induction of thyroid proliferation were investigated in female F344 rats. In the first experiment, rats were divided into 6 groups, each consisting of 5 annuals, and fed a basal diet containing 20% gluten, an iodine-deficient basal diet alone or an iodine-deficient diet containing 0.2%, 1.0%, 5.0% or 25% defatted soybean for 5 weeks. Soybean feeding synergistically induced thyroid hyperplasias with iodine deficiency only at the 25% dose. In the second experiment, rats were also divided into 6 groups, each consisting of 5 animals, and fed a basal diet, a diet containing 20% defatted soybean, 0.025% Sulfadimethoxine (SDM), 20% defatted soybean+0.025% SDM, 0.05% phenobarbital (PB) or 20% defatted soybean+0.05% PB for 5 weeks. The SDM treatments significantly (P<0.05-0.01) increased the thyroid weights, but this increase rate was less prominent in the SDM+soybean group than in the SDM alone group. The PB treatment was also associated with a tendency for increase in thyroid weight, but again this was smaller in the PB+soybean group than in the PB alone group. Although the SDM or PB treatments reduced the serum triiodothyronine and thyroxine levels and consequently increased the serum thyroid-stimulating hormone (TSH) levels, the soybean feeding did not affect or rather attenuated these changes. Our results clearly indicate that soybean feeding does not synergistically enhance the effects of SDM or PB on the rat thyroid. Thus it can be concluded that soybean intake specifically interacts with iodine deficiency in induction of thyroid proliferative lesions in rats, only at high doses.  相似文献   
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54.
目的探讨大豆异黄酮提取物对高胆固醇合并高甘油三酯血症基因工程小鼠的调血脂作用。方法高脂饮食条件下,以C57BL/6成年小鼠10只(65,早5)为正常对照,载脂蛋白E和脂蛋白脂酶双基因缺陷(apoE^-/-/LPL^+/-)成年小鼠(ELK小鼠)40只(620,早20),随机分为4组:高脂模型组,每天200mg/kg大豆异黄酮提取物,每周阳性对照药0.5mg/kg尼尔雌醇和每天20mg/kg洛伐他汀灌胃组。连续灌胃给药4周,测定血清总胆固醇、甘油三酯、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇和血糖含量。结果与C57BL/6空白对照组相比,ELK高脂模型组小鼠的血清TC、TG和LDL—c含量均极显著增高(P〈0.01)。与高脂模型组相比,大豆异黄酮给药4周可显著降低ELK小鼠血清TG含量(P〈0.05),同时使血清HDL—c增加9.3%,而洛伐他汀和尼尔雌醇组分别降低了13.5%和8.7%;高脂诱导的ELK小鼠血清TC、LDL—c水平极度增高,大豆异黄酮、洛伐他汀和尼尔雌醇均不能显著降低TC、LDL-c含量(P〉0.05)。结论大豆异黄酮有明显调血脂作用。  相似文献   
55.
大豆提取液对20种常见致病菌的体外抗菌活性研究   总被引:2,自引:0,他引:2  
目的:观察大豆提取液对20种常见致病菌的体外抗菌作用。方法;采用试管稀释法测定大豆提取液对20种常见致病菌的最低抑菌浓度(MIC)和最低杀菌浓度(MBC)。结果:大豆提取液对大肠杆菌、铜绿假单胞菌、鼠伤寒沙门菌、福氏志贺菌、白色念珠菌、金黄色葡萄球菌、霍乱弧菌等加种常见致病菌的MIC范围在1600-204800μg/ml;MBC范围在1600.102400μg/ml。结论:大豆提取液具有较强的抗菌活性和较广的抗菌谱。  相似文献   
56.
大豆提取物抗氧化作用研究   总被引:2,自引:0,他引:2  
目的:观察大豆提取物对12月龄大鼠抗氧化系统作用的影响.方法:选用SD雄性健康12月龄大鼠,随机分成空白对照组和低、中、高剂量4组.空白对照组给予无菌水,实验组每日分别灌服32、63、190 mg/kg剂量的大豆提取物,连续35 d.第36 d经眼眶取血,测定血清过氧化脂质丙二醛(MDA)含量、超氧化物歧化酶(SOD)活力、谷胱甘肽过氧化物酶(GSH-Px)活力、肝组织中脂褐质含量.结果:与空白对照组比较,中、高剂量组大鼠血清MDA含量、肝脏中脂褐质含量显著降低,高剂量组血清SOD活力升高.结论:大豆提取物具有明显的抗氧化作用.  相似文献   
57.
This review summarizes the history and current state of the known genetic basis for soybean resistance to Soybean mosaic virus (SMV), and examines how the integration of molecular markers has been utilized in breeding for crop improvement. SVM causes yield loss and seed quality reduction in soybean based on the SMV strain and the host genotype. Understanding the molecular underpinnings of SMV–soybean interactions and the genes conferring resistance to SMV has been a focus of intense research interest for decades. Soybean reactions are classified into three main responses: resistant, necrotic, or susceptible. Significant progress has been achieved that has greatly increased the understanding of soybean germplasm diversity, differential reactions to SMV strains, genotype–strain interactions, genes/alleles conferring specific reactions, and interactions among resistance genes and alleles. Many studies that aimed to uncover the physical position of resistance genes have been published in recent decades, collectively proposing different candidate genes. The studies on SMV resistance loci revealed that the resistance genes are mainly distributed on three chromosomes. Resistance has been pyramided in various combinations for durable resistance to SMV strains. The causative genes are still elusive despite early successes in identifying resistance alleles in soybean; however, a gene at the Rsv4 locus has been well validated.  相似文献   
58.
目的:建立测定植物油料(油菜籽、花生、黄豆、玉米、芝麻)中胆固醇含量的超高液相-串联四极杆质谱(UPLC-MS/MS)方法。方法:样品经皂化后用石油醚-乙醚(1∶1)提取,以2,2,3,4,4,6-d6胆固醇为内标,Waters ACQUITYUPLCBEH C18(2.1 mm×50 mm,1.7μm)色谱柱为分析柱,含0.1%甲酸的甲醇溶液为流动相,大气压化学电离源(APCI)正离子模式,多反应检测方式测定。胆固醇和内标离子检测对m/z分别为369.2→146.9,369.2→160.9和375.2→166.5。结果:胆固醇在0.05μg.ml-1~10μg.ml-1范围内线性关系良好(r=0.999),最小检出量为0.1 ng,方法回收率为106%。结论:本方法具有良好的灵敏度、准确度及专属性,可用于植物油料中胆固醇含量测定。  相似文献   
59.
目的对比研究运动和不同高脂肪饮食对大鼠体重和代谢的作用.方法选用幼鼠给予鱼油、棕榈油、大豆油制成的高脂肪饮食,饲养9个月随机分为两组:静坐组和运动组.运动组大鼠持续6周游泳训练,最后一次训练结束24 h后猝死动物,观察体重、胰岛素、血糖、I/G比值和瘦素水平.结果高脂肪大豆饮食大鼠的体重和胰岛素抵抗增加较其他油类饮食的大鼠明显.高脂肪鱼油饮食大鼠体重和胰岛素敏感性与低脂肪饮食的大鼠没有显著差异.结论大豆油、棕榈油的高脂饮食和运动在减少血胰岛素、甘油三酯和瘦素水平,改善胰岛素敏感性中发挥有益的作用.  相似文献   
60.
以普通栽种黄圆豆为对照,对作为保持系88-428的花粉发育全过程及其药壁组织的情况进行了系统的研究.结果表明:①可将这一过程划分为7个时期,即小孢子母细胞形成期、小孢子母细胞减数分裂期、单核早期、单核中期、单核晚期、二胞花粉早期、二胞花粉晚期;②作为保持系的88-428与黄圆豆相比,存有较高的败育率,表现为低不育.  相似文献   
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