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21.
Regev Cohen Talya Finn Frida Babushkin Yael Paran Ronen Ben Ami Alaa Atamna Sharon Reisfeld Gabriel Weber Neta Petersiel Hiba Zayyad Eyal Leshem Miriam Weinberger Yasmin Maor Nicola Makhoul Lior Nesher Galia Zaide Dar Klein Adi Beth-Din Yafit Atiya-Nasagi 《Emerging infectious diseases》2021,27(8):2117
In a multicenter, nationwide, retrospective study of patients hospitalized with spotted fever group rickettsiosis in Israel during 2010–2019, we identified 42 cases, of which 36 were autochthonous. The most prevalent species was the Rickettsia conorii Israeli tick typhus strain (n = 33, 79%); infection with this species necessitated intensive care for 52% of patients and was associated with a 30% fatality rate. A history of tick bite was rare, found for only 5% of patients; eschar was found in 12%; and leukocytosis was more common than leukopenia. Most (72%) patients resided along the Mediterranean shoreline. For 3 patients, a new Rickettsia variant was identified and had been acquired in eastern, mountainous parts of Israel. One patient had prolonged fever before admission and clinical signs resembling tickborne lymphadenopathy. Our findings suggest that a broad range of Rickettsia species cause spotted fever group rickettsiosis in Israel. 相似文献
22.
Catherine A. Hill Felix D. Guerrero Janice P. Van Zee Nicholas S. Geraci Jason G. Walling Jeffrey J. Stuart 《Chromosome research》2009,17(1):77-89
Fluorescent in-situ hybridization (FISH) using meiotic chromosome preparations and highly repetitive DNA from the southern
cattle tick, Rhipicephalus microplus, was undertaken to investigate genome organization. Several classes of highly repetitive DNA elements were identified by screening
a R. microplus bacterial artificial chromosome (BAC) library. A repeat unit of approximately 149 bp, RMR-1 was localized to the subtelomeric
regions of R. microplus autosomes 1–6 and 8–10. A second repeat unit, RMR-2 was localized to the subtelomeric regions of all autosomes and the X
chromosome. RMR-2 was composed of three distinct repeat populations, RMR-2a, RMR-2b and RMR-2c of 178, 177 and 216 bp in length,
respectively. Localization of an rDNA probe identified a single nucleolar organizing region on one autosome. Using a combination
of labeled probes, we developed a preliminary karyotype for R. microplus. We present evidence that R. microplus has holocentric chromosomes and explore the implications of these findings for tick chromosome biology and genomic research.
Electronic supplementary material The online version of this article (doi:) contains supplementary material, which is available to authorized users. 相似文献
23.
目的 澄清三种扇头蜱的存在,列出3种扇头蜱的鉴别要点.方法 从不同自然景观和家、野生动物体上采集蜱类进行分类鉴定.结果 共获得蜱类18 000余只.经鉴定隶属2科5属10种.结论 其中优势蜱种为璃眼蜱属Hyalomma中的种类.其次是扇头蜱属Rhipicephalus、革蜱属Dermacentor、血蜱属Haemaphysalis和钝缘蜱属Ornithodoros的种类. 相似文献
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Haematophagous arthropod vectors such as mosquitoes, tsetse flies, sandflies and ticks have evolved salivary immunomodulatory factors that prevent the vertebrate host from rejecting them meanwhile enhancing pathogen transmission. As dendritic cells (DC) play a major role in host immune responses, we studied the effects of Rhipicephalus sanguineus tick saliva on DC differentiation and maturation. Flow cytometry analysis revealed that the addition of saliva to bone marrow cells inhibits the differentiation of DC and decreased the population of differentiated immature DC, increasing the levels of major histocompatibility complex (MHC) class II while not altering the expression of costimulatory (CD40, CD80 and CD86) and adhesion (CD54) molecules. Furthermore, maturation of DC stimulated by lipopolysaccharide (LPS) in the presence of saliva resulted in a lower expression of costimulatory molecules, but did not alter the up-regulation of MHC class II and CD54. The lipopolysaccharide (LPS)-matured DC cultured with saliva also presented reduced production of interleukin-12, whereas interleukin-10 production was unaltered. Assessment of the function of DC cultured with tick saliva revealed them to be poor stimulators of cytokine production by antigen-specific T cells. Our data indicate a novel modulatory role for the saliva of arthropod vectors at an initial step of the immune response through the inhibition of differentiation and maturation of DC into functional antigen-presenting cells. 相似文献
26.
Oscar E. Zazueta Paige A. Armstrong Adriana Mrquez-Elguea Nstor Saúl Hernndez Miln Amy E. Peterson Diego F. Ovalle-Marroquín Maria Fierro Rodolfo Arroyo-Machado Moises Rodriguez-Lomeli Guillermo Trejo-Dozal Christopher D. Paddock 《Emerging infectious diseases》2021,27(6):1567
Epidemic levels of Rocky Mountain spotted fever (RMSF) have persisted in Mexicali, Mexico, since the initial outbreak was first reported in December 2008. We compared clinical and epidemiologic data of cases in Mexicali during 2009–2019 between patients with an IgG titer reactive with Rickettsia rickettsii bacteria by indirect immunofluorescence antibody (IFA) assay and those who demonstrated DNA of R. rickettsii in a whole blood sample when tested by PCR. We identified 4,290 patients with clinical and epidemiologic features compatible with RMSF; of these, 9.74% tested positive by IFA and 8.41% by PCR. Overall, 140 patients died (11-year case-fatality rate 17.97%). Substantial differences in the frequency of commonly recognized clinical characteristics of RMSF were identified between PCR-positive and IFA-positive cases. The Mexicali epidemic is unique in its size and urban centralization. Cases confirmed by PCR most accurately reflect the clinical profile of RMSF. 相似文献
27.
Elizabeth A. Mitchell Phillip C. Williamson Peggy M. Billingsley Janel P. Seals Erin E. Ferguson Michael S. Allen 《Emerging infectious diseases》2016,22(2):312-315
To describe the presence and distribution of tickborne bacteria and their vectors in Texas, USA, we screened ticks collected from humans during 2008–2014 for Rickettsia, Borrelia, and Ehrlichia spp. Thirteen tick species were identified, and 23% of ticks carried bacterial DNA from at least 1 of the 3 genera tested. 相似文献
28.
Gislaine Cristina Roma Karim Christina Scopinho Furquim Gervásio Henrique Bechara Maria Izabel Camargo-Mathias 《Food and chemical toxicology》2010
The permethrin, active ingredient of the Advantage® Max3 – Bayer, has been widely used in the chemical control of ticks. These ectoparasites are one of the most important animal groups that cause serious damage to their hosts. This study evaluated the toxic effects of permethrin in oocytes of Rhipicephalus sanguineus semi-engorged females subjected to four treatments: group I (control – distilled water), group II (206 ppm of permethrin), group III (1031 ppm of permethrin) and group IV (2062 ppm of permethrin). Results demonstrated that permethrin is a potent chemical agent causing major structural changes in oocytes, such as emergence of large vacuolated cytoplasm regions, reducing the amount of yolk granules and decreasing the size of oocytes, culminating with cell death. As reported in the literature, these oocytes changes, besides affect the tick nervous system, also drastically reduce or prevent the reproduction process in females of R. sanguineus ticks subjected to this compound. 相似文献
29.
E. S. M. Tuppurainen W. H. Stoltsz M. Troskie D. B. Wallace C. A. L. Oura P. S. Mellor J. A. W. Coetzer E. H. Venter 《Transboundary and Emerging Diseases》2011,58(2):93-104
Lumpy skin disease (LSD) is an economically important cattle disease. The disease is endemic in many African countries, but outbreaks have also been reported in Madagascar and the Middle East. The aim of this study was to investigate the potential role of ixodid (hard) ticks in the transmission of the disease. Cattle were infected with a virulent, South African field isolate of lumpy skin disease virus (LSDV). Three common African tick species (genera Rhipicephalus, Amblyomma and Rhipicephalus (Boophilus)) in different life cycle stages were fed on the infected animals during the viraemic stage and on skin lesions. Post‐feeding, the partially fed male ticks were transferred to the skin of non‐infected ‘recipient’ animals, while females were allowed to lay eggs that were then tested using the polymerase chain reaction (PCR) method and virus isolation. Nymphs were allowed to develop for 2–3 weeks after which time they were tested. The non‐infected ‘recipient’ cattle were closely monitored, both skin and blood samples were tested using PCR and virus isolation, and serum samples were tested by the serum neutralization test. This is the first report showing molecular evidence of potential transmission of LSDV by ixodid ticks. The study showed evidence of transstadial and transovarial transmission of LSDV by R. (B.) decoloratus ticks and mechanical or intrastadial transmission by R. appendiculatus and A. hebraeum ticks. 相似文献
30.