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181.
目的 观察以橄榄油为基础脂肪乳的肠外营养对结直肠癌手术患者免疫功能、术后恢复的影响。方法 按前瞻、
随机、盲法、对照的原则,将 80 例结直肠癌腹部手术后重症患者按照随机数表法,随机分为对照组及研究组,两组均给
予规范肠外营养治疗,研究组用橄榄油为基础的脂肪乳(克凌诺,ClinOleic),对照组用普通的中长链脂肪乳,比较两组
患者术后常见并发症的发生率、肛门排气时间、静脉营养时间、术后住院时间、C 反应蛋白水平,探究克凌诺对结直肠癌
患者手术后肠道功能恢复、免疫功能改善的影响,并探究其可能的机制。结果 两组患者一般情况无统计学差异;两组并发
症(咽喉疼痛、恶心呕吐、重新置胃肠减压管、切口感染、肺部感染、肠梗阻、吻合口漏)的发生率无统计学差异(χ
2
=4.512,
P > 0.05);研究组患者免疫功能改善明显,C 反应蛋白在研究组下降(67.470±43.786)mg/L,下降程度显著高于对照组
(t=4.290,P < 0.001);研究组患者术后恢复加快,肛门排气时间、静脉营养时间、术后住院时间均短于对照组,差异有
统计学意义(P < 0.05)。结论 橄榄油脂肪乳能明显改善结直肠癌手术患者免疫功能,促进患者术后胃肠道功能恢复,加
快患者康复。 相似文献
182.
《International journal of pediatric otorhinolaryngology》2014,78(12):2136-2139
ObjectiveThe aim of the present study is to examine the effects of tea tree oil on hearing function and cochlear morphology after intratympanic administration in a chinchilla animal model.MethodsNine chinchillas received intratympanic injection of 3% tea tree oil dissolved in olive oil in one ear, whereas the contralateral control ear received olive oil only. Outcome measures included auditory brainstem responses conducted before treatment and at 10 days and 30 days following the injection. Post-mortem cochlear morphology was assessed using scanning electron microscopy.ResultsAt 10 and 30 days following the injection, there was no significant change in auditory brain response thresholds at 8, 16, 20 or 25 kHz. Scanning electron microscopy imaging showed no damage to auditory hair cells.ConclusionTea tree oil (3%) does not appear to be ototoxic in a chinchilla animal model. Future preclinical and clinical studies are required to establish the effectiveness of TTO in treating otitis. 相似文献
183.
184.
静脉用脂肪乳剂的应用进展 总被引:2,自引:0,他引:2
20世纪60年代,以大豆油(SO)为基础的脂肪乳剂开始应用于临床.但最近研究表明,SO中过多的ω-6PUFA和少量的ω-3PUFA对机体免疫功能不利,并可影响脂质过氧化.为此,各种新型脂肪乳通过改变脂肪乳剂中多不饱和酸、单不饱和酸、饱和脂肪酸含量及来源,期望达到理想的ω-6/ω-3比值.以下就各种脂肪乳剂的营养、供能、... 相似文献
185.
目的采用HPLC法测定橄榄叶中橄榄苦苷的含量。方法采用SHIM-PACK VP-ODS色谱柱(150 mm×4.6 mm,5μm),流动相为乙腈-水(22:78),柱温30℃,流速1 ml.min-1,检测波长282 nm。结果橄榄苦苷的标准曲线为:Y=3.125×106X 179.37(r=0.9997,n=5),1~10μg线性关系良好,平均回收率98.7%,RSD=1.39%。四川达州栽培的不同品种不同生长年限的橄榄叶中橄榄苦苷的含量为1.86%~8.25%,一年生的橄榄叶中橄榄苦苷较两年生者高。结论所建方法稳定、可靠,可用于橄榄叶的质量控制。 相似文献
186.
目的采用UPLC-Q-Exactive四极杆-静电场轨道阱高分辨质谱仪在正、负离子模式下分离鉴定川党参Codonopsis tangshen药材的化学成分。方法 Acquity UPLC BEH C_(18)色谱柱(100 mm×2.1 mm,1.7μm)分离,以乙腈(A)-0.1%甲酸水溶液(B)为流动相进行梯度洗脱,质谱采用正、负离子监测模式、全扫描及自动触发二级质谱扫描功能,对川党参药材的化学成分进行快速分离和鉴定。结果根据高分辨质谱数据从川党参50%甲醇提取物中共鉴定出36个化合物,包括生物碱类7个、苯丙素类7个、多炔类3个、己醇苷与己烯醇苷6个、有机酸类8个、氨基酸类3个、核苷类1个、倍半萜类1个;其中9个成分经与对照品比对而准确鉴定,19个成分在该植物中首次发现,1个成分为潜在的新化合物。结论该方法可快速分离鉴定川党参的化学成分,为其质量控制和药效物质基础研究提供理论依据。 相似文献
187.
Changes in metal speciation and pH in olive processing waste and sulphur-treated contaminated soil 总被引:1,自引:0,他引:1
Degradation of organic matter from olive mill waste and changes in the heavy metal fractionation of a metal-contaminated calcareous soil were studied in a laboratory experiment, in which the olive mill waste was mixed with the soil and then incubated under aerobic conditions. The soil was calcareous (15% CaCO3) with high Zn and Pb concentrations (2058 and 2947 mg kg−1, respectively). The organic amendment was applied at a rate equivalent to 20 g kg−1 soil, and unamended soil was run as a control. To discern if changes in metal solubility were due to the acidic character of the waste, elemental sulphur was applied to soil as a non-organic acidifying material. The S0 rates used were 3.14, 4.71 and 6.28 g kg−1. The mineralisation of total organic-C (TOC) from the waste reached 14.8% of the original TOC concentration after 56 days of incubation. The CO2–C produced from S0-treated soils showed the carbonate destruction by the H2SO4 formed through S0 oxidation. The organic waste increased EDTA-extractable Zn and Pb concentrations and CaCl2-extractable Mn levels in soil after two days of incubation. The changes in metal availability with time indicated that the oxidation of phenols from the waste reduced Mn (IV) oxides, releasing Zn and Pb associated with this mineral phase. Organic waste addition did not decrease soil pH; the acidifying effect of S0 did not change metal fractionation in the soil. 相似文献
188.
《Foot and Ankle Surgery》2023,29(3):233-238
BackgroundMetal screws are the most widely used in treating syndesmotic injuries, but failure and the rigidity of the screws can threaten the success of the treatment and increase the cost of care. We have provided an alternative with an olive wire and external fixator(OWEF) used for syndesmotic fixation.MethodsA retrospective longitudinal follow-up study was conducted. From February 2011 to January 2018, 58 of 72 patients with ankle fractures and associated syndesmotic disruption were treated with either screw or OWEF fixation. The costs, complications, and clinical outcomes using Olerud-Molander score and Visual Analog score in screw and OWEF fixation group were compared.ResultsWe found the severity of the injury, BMI of the patients and the different fixation methods were determinants of the complications and clinical outcomes. But if no malreduction of the syndesmosis was present, no difference in clinical result was detected.ConclusionThe OWEF method appeared to be at least equally functional and effective to screw fixation while maintaining possible lower complication rate.Levels of clinical evidenceLevel 3 相似文献
189.