种植牙技术在牙列游离端缺失患者修复治疗中的应用

目的探究牙列游离端缺失患者采取种植牙修复法治疗的临床效果。方法72例牙列游离端缺失患者,以其就诊时间先后顺序为依据分为对照组与观察组,每组36例。对照组患者行活动义齿修复法治疗,观察组患者行种植牙修复法治疗。比较两组患者修复效果;治疗前后牙槽骨骨吸收量及语言功能评分、咀嚼功能评分、美观度评分;治疗前后生活质量调查表(QOL)评分;术后不良反应发生情况。结果观察组患者的修复总有效率94.44%显著高于对照组的77.78%,差异具有统计学意义(P<0.05)。治疗前,观察组牙槽骨骨吸收量为(0.47±0.15)mm,对照组牙槽骨骨吸收量为(0.46±0.17)mm,两组患者比较差异无统计学意义(P>0.05);观察组治疗后牙槽骨骨吸收量为(0.51±0.15)mm低于对照组的(0.65±0.12)mm,语言功能、咀嚼功能及美观度评分分别为(9.71±0.21)、(8.86±0.35)、(9.26±0.37)分,均高于对照组的(8.02±0.63)、(6.11±0.42)、(7.35±0.46)分,差异均具有统计学意义(P<0.05)。观察组治疗前后QOL评分为(64.40±10.21)、(85.64±7.69)分,对照组治疗前后QOL评分为(63.54±10.15)、(70.25±8.36)分。治疗前,两组患者的QOL评分比较差异无统计学意义(P>0.05);治疗后,两组患者的QOL评分高于治疗前,且观察组患者的QOL评分高于对照组,差异均具有统计学意义(P<0.05)。观察组患者的术后不良反应发生率5.56%低于对照组的25.00%,差异具有统计学意义(P<0.05)。结论种植牙修复法对牙列游离端缺失疗效理想,可有效改善患者咀嚼和语言功能,减少牙槽骨骨吸收量以保证种植牙稳定性,且美观度更显著,因此该种修复方法值得在临床中推广应用。     

Visual grids for managing data completeness in clinical research datasets

Missing data arise in clinical research datasets for reasons ranging from incomplete electronic health records to incorrect trial data collection. This has an adverse effect on analysis performed with the data, but it can also affect the management of a clinical trial itself. We propose two graphical visualization schemes to aid in managing the completeness of a clinical research dataset: the binary completeness grid (BCG) for single patient observation, and the gradient completeness grid (GCG) for an entire dataset. We use these tools to manage three clinical trials. Two are ongoing observational trials, while the other is a cohort study that is complete. The completeness grids revealed unexpected patterns in our data and enabled us to identify records that should have been purged and identify missing follow-up data from sets of observations thought to be complete. Binary and gradient completeness grids provide a rapid, convenient way to visualize missing data in clinical datasets.     

Maxillary Midline diastema closure after replacement of primary teeth with implant prosthesis

This case shows an excellent esthetic treatment outcome using implant‐retained crowns replacing maxillary laterals and canines in hypodontia patient with unusual incidence of spontaneous diastema closure after the placement of implants. To our knowledge, this is the first case report showing maxillary midline diastema closure after implant placement.     

直接法纤维增强复合桥在牙周炎病例中的应用

目的:评价前牙区直接法纤维增强复合桥(FRC bridge)修复单颗切牙缺失伴邻牙松动的牙周炎病例临床应用效果。方法:采用直接法FRC bridge连接所有同颌前牙修复单颗切牙缺失伴邻牙松动的牙周炎病例12例,以弹性义齿修复14例同类病例作为对照,修复后1、6及18个月随访,对临床修复效果以及牙周状况进行评价。结果:修复后1、6或18个月,直接法FRC bridge修复组和对照组解剖外形和边缘适应性均优于弹性义齿修复组(P<0.05);牙周袋探诊深度(PD)及探诊出血指数(BOP)随着观察时间延长而逐渐减小;修复前后PD、BOP、牙齿松动度(TM)差异均存在显著性(P<0.05)。结论:直接法FRC bridge修复单颗切牙缺失伴邻牙松动的牙周炎病例,能达到良好的临床美学修复效果,并可改善邻牙牙周状况。     

家兔一侧颈总动脉缺失探讨

目的 探讨家兔不同条件下一侧颈总动脉缺失对动脉血压的影响,为研究影响动脉血压的作用机制提供数据支持.方法 将24只家兔随机分为实验组和对照组两组,分别进行不同预处理条件下,如正常、麻醉、破坏等四部分夹闭一侧动脉实验,观察另一侧动脉血压的变化.将所得各组数据进行统计学分析,比较动脉血压变化的差异.结果 实验发现,在一侧动脉正常、麻醉、破坏等条件下进一步夹闭该侧颈总动脉,家兔另一侧颈动脉血压明显变化,与操作前比较,差异有统计学意义（P〈0.05或P〈0.01）;实验组动脉血压变化较对照组更为明显（P〈0.05）.但当破坏两侧颈总动脉时,无论是实验前后比较还是组间比较,动脉血压差异均无统计学意义（P〉0.05）.结论 在家兔一侧颈动脉正常、麻醉、破坏等多种条件下,若该侧颈总动脉缺失时,另一侧颈总动脉血压会受到明显的影响,且变化比未缺失时要大.     

Pattern of missing probes in rifampicin resistant TB by Xpert MTB/RIF assay at a tertiary care centre in Mumbai

Setting

Department of Microbiology.

Does an intraabdominally placed LNG-IUS have an adverse effect on fertility? a case report

This case of secondary infertility with an associated intraabdominal levonorgestrel intrauterine system (LNG-IUS) demonstrates the importance of adequate imaging in women with a missing intrauterine contraceptive device and the possible fertility implications of an extrauterine LNG-IUS.     

Short message service text messaging was feasible as a tool for data collection in a trial of treatment for irritable bowel syndrome

ObjectivesTo examine the feasibility of collecting data relating to irritable bowel syndrome (IBS), symptoms by short message service (SMS) text and explore the data to assess its usefulness.Study Design and SettingIn a randomized parallel group design substudy, 59 consenting participants recruited from primary care to a trial of acupuncture for IBS (ISRCTN 08827905) were randomized to receive a one-question SMS message at either 9:30 am or at 6:30 pm for 7 days: “On a scale of 0–9, with 0 being no symptoms and 9 being the worst symptoms you could have, how would you score your IBS symptoms now? Please text back a single number.”ResultsOf the total messages, 59% (n = 203) were answered within 15 minutes, 73.4% (n = 254) within 1 hour, and 97% (n = 334) within 10 hours. Response rates to evening texts were higher (93.5% vs. 87.6% P = 0.05) and response times shorter though not significantly (median: 0 vs. 5 hours; P = 0.12). There was no difference in mean scores, and morning symptoms varied more. Mean scores correlated significantly with IBS trial primary outcome measure, the IBS symptom severity score, and secondary outcome measures.ConclusionAmong IBS trial participants, data collection by SMS is feasible and acceptable, and there is potential for deriving meaningful data from the scores.