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201.
Lewis M. Flint Diana J. Beasley J. David Richardson Hiram C. Polk 《The Journal of surgical research》1979,26(3):280-284
The efficacy of topical 10 and 1.5% povidone-iodine was assessed in a rat fecal peritonitis model. Both solutions were bactericidal in vitro. An LD90 preparation of fecal peritonitis in the rat was then assessed and rats were assigned to control or four treatment groups consisting of lavage with saline, 10% povidone-iodine (2.5 ml/kg), povidone-iodine plus saline (600 ml/kg), or 1% cephalothin (600 ml/kg). Twenty-four-hour mortality rates were recorded. Quantitative peritoneal cultures were obtained before and 3 and 6 hr after lavage. Lavage was effective only with 1.5% povidone-iodine or when cephalothin was added. Each of these lavage solutions significantly reduced mortality (P < 0.05). Delayed intravenous cephalothin (200 mg/kg) reduced mortality significantly following 10 or 1.5% povidone-iodine. Failure of povidone irrigation is due to uncontrolled infection rather than to drug toxicity. 相似文献
202.
203.
J J Schwab 《Psychosomatics》1985,26(7):583-5, 588-9, 592-3
204.
Over a fifteen year period, marginal resection of the mandible was used as all or part of the initial treatment of twenty-three selected patients with squamous cancer of the floor of the mouth. All patients were classified as T1 or T2 on the basis of the extent of the primary tumor. The lesions were lying in the gingivolingual gutter close to the lingual surface of the mandible. Local control rates were obtained that were comparable to the local control rates obtained with other surgical procedures including wider bone excision and with irradiation for patients of the same T classification. 相似文献
205.
206.
Gerald M. Larson Scott Koch Thomas M. ODorisio Bruce Osadehey Patrick McGraw J.David Richardson 《American journal of surgery》1984,147(1):97-105
We studied the gastric response to severe head injury and multiple trauma in 53 patients admitted to the surgical intensive care unit at the University of Louisville. Twenty-two of the 32 patients with severe head injury could have endoscopy. Each patient had gastritis or duodenitis. Patients with severe head injury had a slightly higher rate of gastric acid secretion than did the other trauma patients without severe head injury, but the difference was not significant. Serum gastrin levels were normal in both groups and did not correlate with intracranial pressure. Pancreatic polypeptide levels were significantly higher in patients with severe head injury compared with the control trauma patients without head injury. Elevations in pancreatic polypeptide may be linked to increases in intracranial pressure. We conclude that erosive gastritis occurs commonly in patients with severe head injury and that severe head injury is associated with a marked increase in pancreatic polypeptide levels in the fasted, nongut-stimulated state. Gastrin levels are within normal limits. Head injury appears to specifically increase pancreatic polypeptide release, probably by influencing autonomic centers in the mid brain. Because the cephalic phase of pancreatic polypeptide release is vagalcholinergic, the data are consistent with the hypothesis that severe head injury increases vagal activity. Participation of vagal adrenergic fibers in this process cannot be excluded. 相似文献
207.
Marandapalli R. Sridharan M.D. Leo G. Horan M.D. R. Chris Hand Jennifer C. Johnson M.D. Gurbachan S. Sohi M.D. Nancy C. Flowers M.D. 《Journal of electrocardiology》1981,14(4):399-406
We have analyzed the Wilson ventricular gradient in terms of body surface potential maps and of the reduction of such surface patterns to equivalent dipoles or vectors. While the ventricular gradient traditionally was treated as first a scalar, then a vector concept, we found that the three entities (QRS area, T area, QRST area) did not reduce to vectors with a common location. However, conventional vector addition (QRST area = QRS area + T area) did precisely apply. Further we found considerable more-than-vector or extra-dipolar information remaining for all three entities after removal of the dipole effect. This suggests that maps of these entities should be considered the boundaries of complex electrical fields rather than simple surface effects of vectors. 相似文献