低剂量医用电离辐射作业的习惯性流产妇女淋巴细胞遗传损伤研究

目的分析医用电离辐射作业女性外周血淋巴细胞姐妹染色单体互换(SCE)对习惯性流产的影响。方法随机选择医用电离辐射作业的习惯性流产女性34人和正常的育龄女性20人,检测其外周血淋巴细胞姐妹染色单体互换,记数SCE发生率。结果观察组的外周血淋巴细胞SCE发生率为7.22±0.88,明显高于对照组(P<0.05)。结论 SCE的发生可作为长期小剂量接触电离辐射作业习惯性流产女性染色体结构稳定性的检测指标。这种辐射作业环境中的某些有害物质对女性DNA损伤有一定的影响,可使机体产生一定的辐射损伤。     

Body composition,work capacity,and work efficiency of active and inactive young men

On 46 healthy young men, of whom 18 took part in strenuous sport at least once a week, height, weight, total body fat (as % of body mass) and lean body mass (LBM) were determined. The subjects performed submaximal exercise on a bicycle ergometer and climbing on an upwardly inclined treadmill at work loads of 60, 110, and 140 watts. Oxygen consumption ( ), respiratory quotient (RQ), energy expenditure (), and heart rate (f _H) were measured at rest and at each work load, and maximum oxygen intake ( max) and physical work capacity (PWC₁₅₀, PWC₁₇₀) were calculated.Anthropometric parameters did not differ significantly between sportsmen and sedentary subjects. max, PWC₁₅₀, and PWC₁₇₀ had higher correlations with LBM than with the other anthropometric parameters. max expressed in terms of LBM (ml/kg LBM/min) was the parameter which showed the clearest distinction between sportsmen and sedentary individuals. The sportsmen had higher max on the treadmill test than on the bicycle ergometer. PWC₁₅₀ and PWC₁₇₀ were higher on the bicycle than on the treadmill and had high correlations with max. Work efficiency was of the same order in both groups and showed negative correlation with the degree of obesity on the bicycle ergometer and positive correlation on the treadmill.     

Relationship between habitual physical activity,motor capacity,and capability in children with cerebral palsy aged 4–5 years across all functional abilities

Background

Children with cerebral palsy (CP) have lower habitual physical activity (HPA) than their typically developing peers. There are limited studies of HPA in young children with CP under the age of 5 years.

饮食失宜与慢性萎缩性胃炎相关性探讨

慢性萎缩性胃炎(CAG)属中医学胃痛、痞满等范畴,饮食失宜是其主要发病因素之一。从食量失宜、偏嗜辛辣、恣食生冷热烫、嗜食肥甘厚味、喜食腌制品等多个方面探讨内伤饮食与CAG的关系,尤其指出本病与摄食含有大量亚硝酸盐(I类致癌物质)的腌制品关系更为密切。饮食失宜易导致痰浊、湿热、气机失调,诱发胃痛。     

The accumulation of healthy lifestyle behaviors prevents the incidence of chronic kidney disease (CKD) in middle-aged and older males

Aim

This study was retrospectively designed to evaluate the influence of healthy lifestyle behaviors on the incidence of chronic kidney disease (CKD) during a 5-year follow-up period in middle-aged and older males.

Methods

The subjects included 252 males without a history of cardiovascular disease, stroke, renal dysfunction and/or dialysis treatment who were not taking any medications. Their lifestyle behaviors were evaluated using a standardized self-administered questionnaire and defined as follows: (1) habitual moderate exercise, (2) daily physical activity, (3) fast walking speed, (4) slow eating speed, (5) no late-night dinner, (6) no bedtime snacking and (7) no skipping breakfast. The participants were divided into four categories, which were classified into quartile distributions according to the number of healthy lifestyle behaviors (7–6, 5, 4 and ≤3 groups).

Results

After 5 years, the incidence of CKD [estimated glomerular filtration rate (eGFR) <60 ml/min/1.73 m² and/or proteinuria] was observed in 23 subjects (9.1 %). The Kaplan–Meier survival curves showed that the cumulative incidence of CKD significantly decreased according to an increase in the number of healthy lifestyle behaviors (log-rank test: p = 0.003). According to a multivariate analysis, habitual moderate exercise [hazard ratio (HR) 0.20, 95 % confidence of interval (CI) 0.06–0.69, p = 0.011] and no bedtime snacking (HR 0.19, 95 % CI 0.08–0.48, p = 0.004) were significantly associated with the incidence of CKD.

Conclusions

These results suggest that the accumulation of healthy lifestyle behaviors, especially those related to habitual moderate exercise and no bedtime snacking, is considered to be important to reduce the risk of CKD.

Electronic supplementary material

The online version of this article (doi:10.1007/s12199-016-0506-6) contains supplementary material, which is available to authorized users.     

自拟泻肺清肠汤治疗习惯性便秘90例疗效观察

目的：察自拟泻肺清肠汤治疗习惯性便秘的疗效。方法：将90例习惯性便秘患者随机分为两组,治疗组50例用泻肺清肠汤治疗,对照组40例用酚酞片治疗。均治疗15天判定疗效。结果：治疗组总有效率为96.00%,对照组总有效率为72.50%,两组总有效率比较差异显著（P〈0.05）。结论：泻肺清肠汤治疗习惯性便秘有较好疗效,值得进一步研究。     

寿胎丸治疗习惯性流产23例

目的：探讨寿胎丸对习惯性流产的治疗效果,为习惯性流产治疗提供安全有效方法。方法47例习惯性流产患者,随机分为对照组24例和研究组23例。对照组给予临床常规治疗,研究组在常规治疗的基础上给予寿胎丸治疗,观察对比两组患者治疗效果。结果研究组患者治愈9例,有效12例,总有效率91.30%,对照组患者治愈5例,有效9例,总有效率58.33%,两组比较差异有统计学意义(P<0.05)。结论寿胎丸能够有效降低习惯性流产发生率,治疗安全可靠,临床可积极推广应用。     

肠舒饮治疗习惯性便秘临床观察

为观察肠舒饮治疗习惯性便秘的临床疗效,将72例习惯性便秘（气血亏虚型）患者随机分为两组,治疗组38例采用肠舒饮治疗;对照组34例,予车前番泻颗粒治疗,观察两组用药后情况。结果显示,治疗组和对照组治疗两个疗程后的总有效率分别为92．11％和91．18％（P〉0．05）,不良反应发生率分别为13．16％和35．29％（P〈0．05）。结果表明,肠舒饮治疗习惯性便秘疗效确切,且不良反应少,值得临床推广。     

Analysis of MRI findings in minimum invasive treatment for habitual temporomandibular joint dislocation by autologous blood injection around the temporomandibular joint capsule

The aim of this study was to investigate magnetic resonance imaging (MRI) findings following autologous blood injection (ABI) for habitual temporomandibular joint (TMJ) dislocation. MRI was performed one hour and four and twelve weeks after ABI, revealing three types of significant findings. The first type was similar to hematoma and/or joint effusion in the articular capsule of the TMJ (type I). The second showed sporadic and diffuse T2 emphasis around the TMJ capsule (type II). The third involved a decreased range of condyle movement compared to before ABI (type III). Furthermore, we analyzed the three types of significant MRI findings.At one hour after ABI, type I was Grade 0 in 0 of 14 patients, Grade 1 in 8, Grade 2 in 2, and Grade 3 in 4. Type II was seen in 9 of the 14 cases and type III in 8. After twelve weeks, all cases of type I were Grade 0, no type II cases were evident, and type III was seen in 11 cases. Injecting autologous blood into surrounding TMJ tissues is an important factor in ABI. Minimally invasive treatment for habitual TMJ dislocation using ABI around the TMJ capsule appears to represent a very effective and safe treatment.