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排序方式: 共有3736条查询结果,搜索用时 15 毫秒
41.
目的探讨新生儿先天性心脏病(先心病)的发病情况和预后。方法(1)以彩色多普勒超声心动图配合尸检为主要诊断依据,对1992至1998年我院出生的31493例新生儿进行先心病发病情况前瞻性调查。(2)对1992至1995年出生的先心病患儿,随访3年。结果(1)以彩色多普勒超声心动图配合尸检,结合随访的修正诊断,检得先心病318例,患病率10.10‰。其中非青紫型255例,占80.2%,青紫型63例,占19.8%。室间隔缺损患病率5.14‰居首位。(2)318例先心病中新生儿期死亡35例,病死率11.0%,1992—1995年出生的167例先心病随访3年,死亡38例(22.8%),1岁内占94.7%,0~28d占68.4%。结论新生儿先心病发病率高,新生儿期是先心病死亡高峰年龄。 相似文献
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Applying micro‐costing methods to estimate the costs of pharmacy interventions: an illustration using multi‐professional clinical medication reviews in care homes for older people
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《Acta oto-laryngologica》2012,132(4):50-53
The prognosis of Wegener's granulomatosis (WG) improved following the introduction of immunosuppressant agents. We, however, still experience some difficult cases that are resistant to treatment. Early diagnosis and treatment may improve the prognosis of WG. We reviewed patients with WG attending the Department of Otorhinolaryngology, Kitasato University Hospital. Of the 13 patients reviewed, 5 are still alive. A definite diagnosis was difficult to make without the presence of certain characteristic features. Recently, cytoplasmic antineutrophil cytoplasmic antibody (c-ANCA) has gained importance in the diagnosis of WG and five of our patients were positive for c-ANCA. Close long-term follow-up of WG is recommended: remission was observed in two of our patients and side-effects of the treatment were identified in four. 相似文献
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Long‐term recurrence of soft tissue sarcomas: Prognostic factors and implications for prolonged follow‐up
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Maud Toulmonde MD Axel Le Cesne MD Jean Mendiboure MSc Jean‐Yves Blay MD PhD Sophie Piperno‐Neumann MD Christine Chevreau MD Corinne Delcambre MD Nicolas Penel MD PhD Philippe Terrier MD Dominique Ranchère‐Vince MD Marick Lae MD Sophie Le Guellec MD Jean‐Jacques Michels MD Yves‐Marie Robin MD Carine Bellera PhD Antoine Italiano MD PhD 《Cancer》2014,120(19):3003-3006
48.
Kitchener HC Walker PG Nelson L Hadwin R Patnick J Anthony GB Sargent A Wood J Moore C Cruickshank ME 《BJOG : an international journal of obstetrics and gynaecology》2008,115(8):1001-1007
Objective To evaluate human papillomavirus (HPV) testing in combination with cytology in the follow up of treated women.
Design A prospective study.
Setting Three UK centres: Manchester, Aberdeen and London.
Population or sample Women treated for cervical intraepithelial neoplasia (CIN).
Methods Women were recruited at 6 months of follow up, and cytology and HPV testing was carried out at 6 and 12 months. If either or both results were positive, colposcopy and if appropriate, a biopsy and retreatment was performed. At 24 months, cytology alone was performed.
Main outcome measures Cytology and histology at 6, 12 and 24 months.
Results Nine hundred and seventeen women were recruited at 6 months of follow up, with 778 (85%) and 707 (77.1%) being recruited at 12 and 24 months, respectively. At recruitment, 700 women had had high-grade CIN (grades 2 or 3) and 217 had CIN1. At 6 months, 14.6% were HPV positive and 10.7% had non-negative cytology. Of those with negative cytology, 9% were HPV positive. Of the 744 women who were cytology negative/HPV negative at baseline, 3 women with CIN2, 1 with CIN3, 1 with cancer and 1 with vaginal intraepithelial neoplasia (VAIN)1 were identified at 24 months. Nine of 10 cases of CIN3/cervical glandular intraepithelial neoplasia (CGIN) occurred in HPV-positive women. At 23 months, cancer was identified in a woman treated for CGIN with clear resection margins, who had been cytology negative/HPV negative at both 6 and 12 months.
Conclusions Women who are cytology negative and HPV negative at 6 months after treatment for CIN can safely be returned to 3-year recall. 相似文献
Design A prospective study.
Setting Three UK centres: Manchester, Aberdeen and London.
Population or sample Women treated for cervical intraepithelial neoplasia (CIN).
Methods Women were recruited at 6 months of follow up, and cytology and HPV testing was carried out at 6 and 12 months. If either or both results were positive, colposcopy and if appropriate, a biopsy and retreatment was performed. At 24 months, cytology alone was performed.
Main outcome measures Cytology and histology at 6, 12 and 24 months.
Results Nine hundred and seventeen women were recruited at 6 months of follow up, with 778 (85%) and 707 (77.1%) being recruited at 12 and 24 months, respectively. At recruitment, 700 women had had high-grade CIN (grades 2 or 3) and 217 had CIN1. At 6 months, 14.6% were HPV positive and 10.7% had non-negative cytology. Of those with negative cytology, 9% were HPV positive. Of the 744 women who were cytology negative/HPV negative at baseline, 3 women with CIN2, 1 with CIN3, 1 with cancer and 1 with vaginal intraepithelial neoplasia (VAIN)1 were identified at 24 months. Nine of 10 cases of CIN3/cervical glandular intraepithelial neoplasia (CGIN) occurred in HPV-positive women. At 23 months, cancer was identified in a woman treated for CGIN with clear resection margins, who had been cytology negative/HPV negative at both 6 and 12 months.
Conclusions Women who are cytology negative and HPV negative at 6 months after treatment for CIN can safely be returned to 3-year recall. 相似文献
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影响人群健康的心理社会因素随访比较研究 总被引:2,自引:1,他引:2
目的:运用应激理论和综合健康概念,研究影响人群健康的心理社会因素及其一年间变化。方法:抽取简阳市某厂1160名职工为研究对象,进行基线调查和一年后随访。以问卷和临床检查相结合调查其社会人口学特征、应激性生活事件、心理健康状况、社会支持和社会功能及现患疾病,并进行单因素和多元线性回归分析。结果:1997年影响该人群疾病总分的主要因素有工种、年龄、阳性症状数、阳性症状均分、主观支持分,R^2=0.32;1998年的主要因素有年龄、SCL-90总分、阳性症状均分、支持利用度,R^2=0.345。结论:年龄、心理应激水平、社会支持等是影响人群健康的主要心理社会因素,且一年时间变化不大。 相似文献