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ObjectiveThe Biological Rhythms Interview of Assessment in Neuropsychiatry (BRIAN) might be applicable for assessing delayed sleep-wake phase disorder (DSWPD). We aimed to investigate the reliability and validity of the Japanese version of the BRIAN self-report (J-BRIAN-SR) in DSWPD patients and determine a cutoff score to identify the presence of the disorder.MethodsWe enrolled 60 newly diagnosed DSWPD outpatients and 64 age-matched healthy controls. We used Cronbach's alpha for internal reliability to evaluate J-BRIAN-SR. We confirmed the reliability of the A test and re-test using Pearson's correlation coefficient in the controls. We used confirmatory factor analysis to evaluate the factor structure of J-BRIAN-SR and referenced the Morningness-Eveningness Questionnaire (MEQ) to check concurrent validity. We analyzed the receiver operating characteristic curve (ROC) to determine the J-BRIAN-SR cutoff point for the presence of DSWPD.ResultsThe 18-component scores of the J-BRIAN-SR had an overall reliability coefficient (Cronbach's alpha) of 0.82. We confirmed a high test-retest reliability using an intraclass correlation coefficient (r = 0.84). The correlation between J-BRIAN-SR and MEQ was 0.38 (p = 0.003). The J-BRIAN-SR that we extracted by exploratory factor analysis consisted of three factors. A score of 40 points provided a sensitivity of 80.0% and a specificity of 75.6% for the positivity of DSWPD.ConclusionsThe results of the present study revealed that J-BRIAN-SR is a valid and reliable instrument for screening and evaluating the severity of DSWPD. Our findings will be useful to physicians and patients in Japan and those in clinical settings.  相似文献   
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临床上食管测压常用于评估咽喉部压力,或作为咽喉部手术术前和术后功能评估的手段之一。以往常规使用液体灌注方法进行咽喉部压力测定。更先进的食管测压方法则能提供更详细的口咽部压力数据。我科近期采用固态高分辨食管测压联合阻抗评估喉部外伤患者术前和术后吞咽功能,现报道如下。  相似文献   
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BackgroundMarijuana use is increasingly prevalent in the United States. Effects of marijuana use on sexual function are unclear, with contradictory reports of enhancement and detriment existing.AimTo elucidate whether a relation between marijuana use and sexual frequency exists using a nationally representative sample of reproductive-age men and women.MethodsWe analyzed data from cycle 6 (2002), cycle 7 (2006–2010), and continuous survey (2011–2015) administrations of the National Survey of Family Growth, a nationally representative cross-sectional survey. We used a multivariable model, controlling for demographic, socioeconomic, and anthropographic characteristics, to evaluate whether a relationship between marijuana use and sexual frequency exists.OutcomesSexual frequency within the 4 weeks preceding survey administration related to marijuana use and frequency in the year preceding survey administration.ResultsThe results of 28,176 women (average age = 29.9 years) and 22,943 men (average age = 29.5) were analyzed. More than 60% of men and women were Caucasian, and 76.1% of men and 80.4% of women reported at least a high school education. After adjustment, female monthly (incidence rate ratio [IRR] = 1.34, 95% CI = 1.07–1.68, P = .012), weekly (IRR = 1.36, 95% CI = 1.15–1.60, P < .001), and daily (IRR = 1.16, 95% CI = 1.01–1.32, P = .035) marijuana users had significantly higher sexual frequency compared with never users. Male weekly (IRR = 1.22, 95% CI = 1.06–1.41, P = .006) and daily (IRR = 1.36, 95% CI = 1.21–1.53, P < .001) users had significantly higher sexual frequency compared with never users. An overall trend for men (IRR = 1.08, 95% CI = 1.05–1.11, P < .001) and women (IRR = 1.07, 95% CI = 1.04–1.10, P < .001) was identified showing that higher marijuana use was associated with increased coital frequency.Clinical ImplicationsMarijuana use is independently associated with increased sexual frequency and does not appear to impair sexual function.Strengths and LimitationsOur study used a large well-controlled cohort and clearly defined end points to describe a novel association between marijuana use and sexual frequency. However, survey responses were self-reported and represent participants only at a specific point in time. Participants who did not answer questions related to marijuana use and sexual frequency were excluded.ConclusionA positive association between marijuana use and sexual frequency is seen in men and women across all demographic groups. Although reassuring, the effects of marijuana use on sexual function warrant further study.Sun AJ, Eisenberg ML. Association Between Marijuana Use and Sexual Frequency in the United States: A Population-Based Study. J Sex Med 2017;14:1342–1347.  相似文献   
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