电针肺俞穴对支气管哮喘患者(急性发作期)临床症状与肺功能的影响

目的:探讨电针对哮喘患者肺功能的影响。方法:将92例哮喘患者随机分为治疗组(46例)和对照组(46例)。治疗组采用电针,取肺俞穴,每次30 min,每日1次,2周为1疗程(疗程期间不休息);对照组口服舒氟美,每次200 mg,每日两次口服,2周为1疗程(疗程期间不休息)。观察时间共为2周,治疗结束后两周进行随访,随访1次。结果:治疗组的总有效率为97.56%,对照组为92.50%,两组疗效比较差异有统计学意义(P0.05)。结论:电针肺俞穴能显著改善支气管哮喘(急性发作期)喘息、气短、咳嗽、咯痰等症状,使患者生活质量明显提高;在肺功能指标方面,电针肺俞穴能显著提高PEF、FEV1、FVC、FEV1%水平,从而为症状改善提供了客观依据。     

电针干预海洛因依赖者戒断后抑郁症的临床观察

目的：观察电针治疗海洛因依赖者戒断后抑郁症的临床疗效。方法：60例海洛因依赖者经脱毒治疗后，尿检吗啡阴性，随机分为2组，即对照组和针刺组。于治疗前、治疗1周、治疗2周、治疗3周，用汉密尔顿抑郁量表对患者进行评定。结果：治疗后针刺组在改善海洛因依赖者的抑郁方面优于对照组（P〈0．05）。结论：电针能较快改善海洛因依赖者的抑郁症状和情绪。     

Electro-acupuncture vs. sham electro-acupuncture for chronic severe functional constipation: A systematic review and meta-analysis

ObjectivesTo assess the efficacy of electro-acupuncture (EA) relative to sham electro-acupuncture (sham EA) in treating chronic severe functional constipation (CSFC). Methods: A comprehensive search for relevant studies published between January 1, 1951 and May 14, 2020 was conducted in PubMed, the Cochrane Library, Chinese Biomedical Literature Database, Web of Science, and EMbase. Two investigators independently selected studies, extracted data, and assessed the quality of the included studies. The software Endnote X9 was used for screening articles, and the Review Manager 5.3 for analyzing data.ResultsThe meta-analyses involved 6 studies and 1457 individuals. The pooled results favored the EA group for the increase of complete spontaneous bowel movements (CSBMs) per week in the fourth week (MD = 0.80, P = 0.001) during treatment, and further improved in the eight weeks (MD = 1.25, P < 0.001). During the follow-up period, significant changes in CSBMs per week were seen in the experimental group (MD = 1.38, P = 0.008); the effect decreased in the twelfth week (MD = 0.87, P < 0.001). There was no significant difference in the Bristol stool scale score between the two groups in the fourth week (MD = 0.40, P = 0.08), but significant differences were observed in the eighth week (MD = 0.40, P = 0.03). A significant reduction in patient assessment of constipation quality of life (PAC-QOL) score were observed in the EA group during treatment (SMD = -0.83, P < 0.001). No serious adverse events were reported.ConclusionsEA had favorable effects on CSFC, and the longer the treatment duration was, the better was the effect, but the effect showed a certain period of validity. However, the results may be influenced by the clinical heterogeneity of acupuncture points, depth of needling, intensity, and frequency of EA.     

硬膜外阻滞复合异氟醚麻醉时电针对镇静深度的影响

目的：以听觉诱发电位指数（AAI）和脑电双频谱指数（BIS）为镇静深度监测指标，观察硬膜外阻滞复合异氟醚麻醉时电针的影响。方法：选择择期上腹部手术，实施硬膜外阻滞复合异氟醚麻醉的患者24例。根据异氟醚肺泡最低有效浓度（MAC）随机分为Ⅰ组（0．4MAC）、Ⅱ组（0．6MAC）、Ⅲ组（0．8MAC）3组。术中针刺合谷、内关穴，记录各个时间点从I、BIS的变化。结果：电针后，3组BIS以及Ⅱ组、Ⅲ组AAI均无显著差异（P〉0．05）；Ⅰ组AAI与电针前即刻相比，除在电针时有显著升高（P〈0．05），2min后恢复，其余各个时间点均无显著差异（P〉0．05）。结论：电针在硬膜外阻滞复合异氟醚麻醉状况下对镇静深度无明显作用。     

不同频率电针“内关”穴对急性心肌缺血模型家兔心交感神经电活动的影响

目的通过观察心交感神经电活动变化情况,比较不同频率电针对穴位效应的影响,为临床治疗选择低频电针频率提供实验依据。方法健康青紫蓝家兔60只,雌雄各半,体质量(2.5±0.3)kg,随机选10只做正常对照组,其余家兔在麻醉状态下采用左冠状动脉旋前降支结扎法复制急性心肌缺血模型,随机分为模型对照组、低频(2 Hz)电针组、高频(100Hz)电针组和混频(2/100 Hz)电针组,每组10只。采用BIOPAC生物信号采集系统记录心交感神经电信号,同时接入SKY-A8生物信号处理系统进行数据处理。结果急性心肌缺血模型家兔心交感神经电活动兴奋性降低,与正常组家兔比较有显著性差异(P<0.01)。在电针后即刻及停针15min时,心交感神经电活动显著增强,低频电针组、高频电针组及混频电针组家兔的心交感神经电活动的频率与模型组有显著性差异,且以低频电针组效果优于高频电针组和混频电针组,而高频电针组和混频电针组之间无显著性差异(P>0.05)。结论不同频率电针"内关"穴均可明显改善急性心肌缺血家兔的心交感神经电活动,且存在相对特异性,以低频电针组提高心交感神经兴奋性作用最强。     

急性期重灸翳风结合电针推拿治疗面瘫36例

目的 观察急性期重灸翳风结合针灸推拿与单纯电针对治疗周围性面瘫的疗效之差异.方法 将面瘫患者72例随机分为治疗组和对照组各36例.急性期治疗组采用重灸患侧翳风及阳白、下关、牵正、迎香、地仓等穴,对照组只在患侧翳风及面部周围用TDP照射,2组均同时辅予相同的西药治疗.进入稳定期和恢复期后2组均采用电针治疗配合推拿疗法,2组均治疗30d后观察疗效.结果 治疗组总有效率为97.2%;对照组为83.3%,治疗组疗效优于对照组(P＜0.05).结论 急性期重灸翳风等穴结合电针推拿治疗周围性面瘫的临床疗效优于单纯电针治疗.     

电针对活动性类风湿关节炎患者外周血与关节滑液中TNF-α与VEGF的影响

目的:观察电针对活动性类风湿关节炎(RA)患者外周血和关节滑液中肿瘤坏死因子α(TNF-α)与血管内皮生长因子(VEGF)的指标改变,确定电针对RA的临床治疗作用。方法:采用随机对照的研究方法,将68例活动性类风湿关节炎患者分为电针组(34例)与对照组(即单纯针刺组,34例)。采取整体与局部相结合的配穴方法,整体取穴以阳经为主,局部取穴依以痛为腧原则,疏经通络,祛风止痛。隔日1次,10次为1个疗程,共治疗3个疗程。结果:电针与单纯针刺对患者外周血和关节滑液中TNF-α与VEGF均有较为显著的作用(P0.05),电针组对关节滑液中TNF-α的改善作用等同于单纯针刺组,但在外周血的作用上优于单纯针刺组(P0.05);治疗后在外周血和关节滑液中VEGF降低,电针组的效应均优于单纯针刺组(P0.05)。结论:电针能有效的降低活动性RA患者外周血和关节滑液中TNF-α与VEGF的含量,改善RA发生、发展的内环境,提高临床效果。     

针刀和电针对膝骨关节炎大鼠痛阈和中枢单胺类神经递质的影响

目的:对比观察针刀松解法、电针对膝骨关节炎(KOA)大鼠痛阈和中枢神经递质的影响。方法:80只SD大鼠被随机分为空白对照组、模型组、针刀组和电针组,4%木瓜蛋白酶溶液与0.3 mol/L半胱氨酸溶液(1∶1混置0.5 h)的混合液20μL,分别于造模第1 d、4 d、7 d注射于大鼠左侧膝关节腔中,4周后,治疗组分别以针刀松解法或电针治疗,共3周。采用光辐射热法检测大鼠痛阈,膝关节HE染色,ELISA法分别测定大鼠中脑、下丘脑、延脑、海马、脊髓等不同部位5-HT、NE、DA含量。结果:膝骨关节炎大鼠造模后痛阈显著降低(P0.01),而针刀松解法或电针治疗后,第1周、第2周、第3周痛阈值均明显高于模型组(P0.05,P0.01);针刀和电针疗法可以改善大鼠膝骨关节炎病理组织损伤,可调节大鼠中脑、下丘脑、海马、脊髓等部位5-HT的合成与代谢,调节脊髓、下丘脑和延脑NA合成和代谢,调节中脑DA合成与代谢。结论:针刀和电针疗法对膝骨关节炎大鼠痛阈、组织形态学和中枢单胺类神经递质的含量有一定的调节作用。提示2种疗法可通过调节中枢神经5-羟色胺和儿茶酚胺类神经递质的合成和代谢的失衡状态,以减轻关节软骨损伤,缓解膝骨关节炎发生发展时出现的疼痛。     

电针对腹部术后胃瘫综合征的干预治疗

目的:评价电针对腹部术后胃瘫综合征(PGS)的治疗价值。方法:将41例PGS患者随机分为针灸干预组24例,常规对照组17例,对照组采用常规治疗,针灸干预组采用常规加电针治疗。观察术后恢复时间。结果:针灸干预组与常规对照组相比,多数患者在2周内治愈,有显著差异。结论:腹部术后早期配合电针治疗,能加速胃肠功能恢复。     

Influences of electro-acupuncture at related Jing-well Points in rats with vascular dementia

OBJECTIVE:To observe the effects of electro-acupuncture(EA) at related Jing-well Points(HT 9,PC 9,KI 1 and LU 11) in rats with vascular dementia(VD) and discuss the relative mechanism.METHODS:A randomized controlled animal experiment was designed.A total of 104 rats were involved in the present study and divided randomly into 4 groups:sham-operation group,model group,Jing-well Points group,and medication group.The VD model was established according to the modified 4-vessel occlusion(4-VO) method.VD rats in the Jing-well Points group were treated by EA at the related Jing-well Points(HT 9,PC 9,KI 1 and LU 11) while those in the medication group were treated with nimotop.The step-down avoidance test was performed before and after treatment in all rats.Latency and error frequency indexed memory function were recorded.Nitric oxide(NO) levels and superoxide dismutase(SOD) activity in both cerebral tissue and serum were detected after the treatment course.RESULTS:A total of 42 rats were included in the final analysis.Compared with the model group,the latency in the Jing-well Points group was significantly prolonged(P<0.01) and the error frequency was significantly decreased(P<0.05) after therapy;the decrease in NO levels in both brain tissue and serum was significant(P<0.05 and P<0.01,respectively);and the increase in SOD activity was also significant(P<0.01).There was no significant difference in latency,error frequency,NO levels and SOD activity between the Jing-well Points group and medication group.CONCLUSION:EA at related Jing-well Points can remarkably improve memory impairment in VD rats.Moreover,decreasing the overproduction of NO and strengthening the ability of eliminating free radicals may provide therapeutic potential for the treatment of VD.