全文获取类型
收费全文 | 147174篇 |
免费 | 11073篇 |
国内免费 | 3537篇 |
专业分类
耳鼻咽喉 | 864篇 |
儿科学 | 3790篇 |
妇产科学 | 1535篇 |
基础医学 | 9611篇 |
口腔科学 | 1450篇 |
临床医学 | 21271篇 |
内科学 | 36232篇 |
皮肤病学 | 769篇 |
神经病学 | 4372篇 |
特种医学 | 3247篇 |
外国民族医学 | 8篇 |
外科学 | 14409篇 |
综合类 | 26156篇 |
现状与发展 | 11篇 |
一般理论 | 4篇 |
预防医学 | 11407篇 |
眼科学 | 572篇 |
药学 | 13784篇 |
203篇 | |
中国医学 | 8951篇 |
肿瘤学 | 3138篇 |
出版年
2024年 | 396篇 |
2023年 | 2456篇 |
2022年 | 4377篇 |
2021年 | 6182篇 |
2020年 | 6223篇 |
2019年 | 5243篇 |
2018年 | 5352篇 |
2017年 | 5026篇 |
2016年 | 5250篇 |
2015年 | 5165篇 |
2014年 | 11027篇 |
2013年 | 11152篇 |
2012年 | 9225篇 |
2011年 | 9779篇 |
2010年 | 7629篇 |
2009年 | 7008篇 |
2008年 | 6738篇 |
2007年 | 6848篇 |
2006年 | 5991篇 |
2005年 | 5429篇 |
2004年 | 4363篇 |
2003年 | 3860篇 |
2002年 | 3156篇 |
2001年 | 2887篇 |
2000年 | 2333篇 |
1999年 | 2182篇 |
1998年 | 1809篇 |
1997年 | 1696篇 |
1996年 | 1456篇 |
1995年 | 1389篇 |
1994年 | 1355篇 |
1993年 | 978篇 |
1992年 | 899篇 |
1991年 | 836篇 |
1990年 | 706篇 |
1989年 | 657篇 |
1988年 | 579篇 |
1987年 | 502篇 |
1986年 | 442篇 |
1985年 | 560篇 |
1984年 | 486篇 |
1983年 | 299篇 |
1982年 | 352篇 |
1981年 | 289篇 |
1980年 | 262篇 |
1979年 | 194篇 |
1978年 | 187篇 |
1977年 | 145篇 |
1976年 | 132篇 |
1975年 | 82篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
91.
92.
David Langton Diana Way Lisbeth Trigg Duncan Blake Barry McGrath 《Clinical and experimental pharmacology & physiology》1990,17(3):219-223
1. The effects of graded treadmill exercise on renal blood flow (RBF) were examined in seven rabbits, in which congestive heart failure (CHF) was produced by the administration of doxorubicin, 1 mg/kg, twice weekly for 8 weeks, and in seven controls. A third group of five rabbits underwent doxorubicin treatment with the addition of surgical section of the left renal sympathetic nerve. 2. During submaximal exercise, there was a small reduction in RBF in controls, which was greatly exaggerated in CHF. 3. In both control and heart failure rabbits, there was a precipitous fall in RBF as exercise fatigue developed. 4. Renal sympathectomy ablated these changes in RBF during exercise. 5. It is concluded that in heart failure there is an exaggerated, sympathetically mediated, diversion of blood flow away from the kidney. The onset of exercise fatigue in both normal and heart failure rabbits is accompanied by a marked intensification of this process. 相似文献
93.
在海拔3417m对18名健康世居藏族和16名移居汉族用Jeager气体代谢自动分析系统和心阴抗图测定了无氧阈和最大摄氧量时的SV、CO、PEP/LVET和SaO2。结果显示:在海拔3417m测得AT值明显低于海平面;世居藏族AT出现较晚,并且AT时的功率、VO2、MV、HR、CO、SV均高于移居汉族,而PET/LVET比值小于移居组;两组的SV峰值出现时间不同,蕊居组在AT或AT以后出现的占72% 相似文献
94.
Risk factors for coronary heart disease among inpatients who have mild intellectual disability and mental illness 总被引:1,自引:1,他引:0
S. Merriman C. Haw J. Kirk & J. Stubbs 《Journal of intellectual disability research : JIDR》2005,49(5):309-316
Background Coronary heart disease (CHD) is a major cause of morbidity and mortality in the UK. The aim of this study was to screen inpatients with mild or borderline intellectual disability, many of whom also have mental illness, for risk factors for CHD. Methods Cross sectional survey. Participants were interviewed, measured and had blood samples taken. Results Of the 53 participants, 20 (37.7%) were overweight and 18 (34.0%) obese. The mean body mass index (BMI) of those participants prescribed regular antipsychotics was higher than those who were not. Nine (20.9%) had waist circumference measurements placing them at increased risk of CHD and 21 (48.8%) were at substantially increased risk. Twenty-eight (52.8%) were current smokers. Of the 49 participants who had their blood pressure measured, 3 (6.1%) had readings above the reference range. Of the 19 participants who had random blood tests, one (5.3%) had an elevated cholesterol level. Conclusions In this population there was a high prevalence of two risk factors for CHD (obesity and smoking), requiring ongoing monitoring and long-term measures to reduce risk. 相似文献
95.
重组人红细胞生成素治疗肾性贫血的临床分析 总被引:1,自引:0,他引:1
目的 观察重组人红细胞生成素 (RhEPO)对肾性贫血的治疗作用。方法 根据使用EPO剂量的不同将 39例慢性肾衰竭并血液透析病人分成 4组 ,观察治疗后 2、4、12个月时与治疗前 (0月 )相比红细胞数 (RBC)、红细胞比积 (Hct)及血红蛋白含量 (Hb)的变化。结果 2 4例使用EPO10 0 - 15 0IU/ (kg·w) (6 0 0 0IU/w - 90 0 0IU/w) ,治疗后RBC、Hct、Hb较治疗前有显著升高 (P≤ 0 .0 0 1) ;5例使用EPO5 0IU/ (kg·w) (30 0 0IU/w) +间断输血患者 ,其RBC、Hct、Hb升高不显著 ;10例不用EPO而单纯输血患者 ,其RBC、Hct、Hb无明显变化 (P >0 .0 5 )。结论 EPO能较好地纠正肾性贫血 ;单纯输血不能治疗肾性贫血 相似文献
96.
BACKGROUND: Patient education is integral part of any diabetes therapy in Germany, but elderly patients are not able to follow the variety of topics comprising standard treatment and teaching programmes (TTP), primarily due to impaired neuropsychological function. This leads to deficits in diabetes knowledge and hindered ability for diabetes self-management. AIM: To evaluate structured TTP for geriatric patients with impaired cognitive function. PATIENTS AND METHODS: A neuropsychological examination was performed on all patients over 54 years [n=102, age 68.6 +/- 8.7 years, diabetes duration 10.3 (0.03-35.4) years, HbA1c 10.3 +/- 1.7% (HPLC, Diamat, NR 4.5-6.3%), cognitive function 87.7 +/- 12.3 IQ points] who took part in TTP for insulin therapy. Patients with impaired cognitive function participated either in the standard TTP of Berger [n = 35, age 67.6 +/- 8.9 years, diabetes duration 9.9 (0.04-35.4) years, HbA1c 10.3 +/- 2.0%] or in the specialized structured geriatric DICOF-TTP [n=33, age 70.4 +/- 8.2 years, diabetes duration 10.4 (0.03-24.9) years, HbA1c 10.7 +/- 1.8%]. RESULTS: After TTP there were no differences in knowledge and ability for diabetes self-management (standard/DICOF: knowledge 11.0 +/- 2.6 vs. 12.2 +/- 2.7 points, P = 0.11; handling 14.9 +/- 3.3 vs. 15.9 +/- 2.5 points, P = 0.18). However, patients who took part in the DICOF programme showed better scores in satisfaction with the education programme [standard/DICOF 44.7 (31-57) vs. 52.5 (45-59) points, P < 0.001]. Six months later the DICOF participants showed better results regarding diabetes self-management (standard/DICOF: handling 12.5 +/- 4.1 vs. 15.9 +/- 3.1 points, P = 0.001). Both groups showed HbA1c decrease (8.3 +/- 1.4 vs. 8.5 +/- 1.3%, P=0.62) and similar incidence of acute complications. CONCLUSIONS: Elderly patients with impaired cognitive function should take part in specialized structured TTP. This leads to both better satisfaction with the education programme and an improved ability for diabetes self-management. 相似文献
97.
R S Rodger W L Sheldon M J Watson J H Dewar R Wilkinson M K Ward D N Kerr 《Nephrology, dialysis, transplantation》1989,4(10):888-892
We selected a group of male dialysis patients complaining of sexual dysfunction in whom penile vascular insufficiency and drug-induced impotence had been excluded. Monitoring of nocturnal penile tumescence was used to confirm organic disturbance. Patients with normal serum prolactin concentrations (n = 18) had significantly lower serum zinc values than normal controls (P less than 0.001) and were entered in a 6-month double-blind study comparing oral zinc acetate with placebo. Patients with elevated prolactin concentrations (n = 8) were entered in a 3-month double-blind crossover study comparing oral pergolide mesylate with placebo. In the zinc study, serum zinc concentrations increased (P less than 0.05) in the zinc-treated but not the placebo-treated group. One of nine patients receiving zinc reported improved sexual function, as did two of nine patients receiving placebo. There were no significant changes in sperm counts, nocturnal penile tumescence, testosterone, sex hormone binding globulin or gonadotrophin concentrations in either treatment group. In the pergolide study, serum prolactin values decreased (P less than 0.01) in the pergolide but not in the placebo treatment period. One patient reported improved sexual function during the pergolide treatment period and two during the placebo period. There were no significant changes in sperm counts, nocturnal penile tumescence, testosterone, sex hormone binding globulin or gonadotrophin concentrations after pergolide. These studies show no benefit of zinc or pergolide compared with placebo in the treatment of uraemic impotence. 相似文献
98.
99.
100.