^99mTc-MDP骨显像联合CT对乳腺癌术后早期随访的临床价值

目的^99mTc-MDP骨显像联合CT对乳腺癌术后早期随访，监测其复发及转移的临床应用价值。方法81例乳腺癌手术化疗后3年内的病人，女性，年龄29—65岁，分别行^99mTc-MDP骨显像、CT显像、计算灵敏度、特异性、准确性。结果81例乳腺癌手术化疗后病人中，经病理检查或临床及其他影像学诊断转移的31例，^99mTc-MDP骨显像诊断骨转移的15例，CT显像诊断复发及转移的病例18例，^99mTc-MDP骨显像对骨转移的灵敏度、特异性、准确性分别为93．8％、90．8％、91．4％，CT显像对复发及转移的灵敏度、特异性、准确性分别为58．1％、88．0％、93．8％、90．8％、91．4％，其对骨转移的灵敏度、特异性、准确性分别为51．2％、91．0％、88．4％。CT联合^99mTc-MDP骨显像诊断复发及转移的灵敏度、特异性、准确性分别为94．3％、90．6％、93．3％。结论CT对乳腺癌术后病人软组织的复发及转移有较高的灵敏度，但对于骨转移病灶不及^99mTc-MDP骨显像敏感。因此，两者联合应用可明显提高乳腺癌术后复发及转移的灵敏度、特异性和准确性，对监测其复发及转移具有重要的临床应用价值。     

Topographic organization of orientation columns in the cat visual cortex

Summary Three-dimensional reconstructions of the orientation column system were obtained from the visual cortex of four cats using the deoxyglucose technique. One cat had normal visual experience, one was monocularly deprived and two had selective experience with vertical and horizontal contours, respectively. In areas 17 and 18 orientation columns form a remarkably regular system of equally spaced parallel bands whose trajectory is orthogonal to the borderline between areas 17 and 18. This topographic organization is resistant to manipulations of early visual experience.