Lingual Cysticercosis: A Case Series with Review of Literature

Cysticercosis is a condition in which humans are infected by the larval form of Pork Tapeworm Taenia solium. Isolated lingual cysticercosis is a rare entity due to the high muscular activity and metabolic rate of tongue which prevents the development of larva. We present a series of three patients with isolated lingual cysticercosis. One patient was treated by medical management while the other two were treated with surgical excision followed by medical therapy. All patients are asymptomatic after repeated follow ups.     

168例猪囊虫病心理障碍患者的临床资料分析

目的了解有心理障碍的猪囊虫病患者分布和发病特点及治疗情况,为防治提供依据。方法从2005-2006年经山东省寄生虫病防治研究所确诊的猪囊虫病住院患者中,挑选168例有心理障碍的病例进行调查和统计分析。结果168例患者中,山东籍150例（89.29%）,分布于全省16个地级市。农村患者与城镇患者之比为2.45∶1;男女患者之比为2.43∶1;年龄以18-45岁的中青年患者所占比例最高,为64.80%;临床分型以脑囊虫病所占比例最高,为76.79%。所有患者共分4种心理类型,其中消极悲观型占36.31%,忧郁自卑型占31.55%,焦虑恐惧型占24.40%,对抗偏执型占7.74%。用吡喹酮（PQT）结合阿苯哒唑（ALB）治疗后,总有效率为98.21%,治愈率为45.24%。结论山东省猪囊虫病仍处于较高的发病态势,患者以农村男性中青年占多数;吡喹酮（PQT）和阿苯哒唑（ALB）联合应用仍是目前猪囊虫病的有效治疗方法。     

囊尾蚴病患者红细胞免疫粘附功能的研究

目的 :探讨囊尾蚴病患者红细胞免疫粘附功能 ( RCIA)变化及其机制。方法 :用酵母菌标记技术检测囊尾蚴病患者红细胞表面 C3b受体活性及 RCIA调节因子活性 ;用琼脂单扩散法测血清补体 C3含量 ,用聚乙二醇 -紫外分光法测血清 CIC含量。结果 :囊尾蚴病患者红细胞膜 C3b受体花环率及血清 RCIA增强因子活性明显低于正常对照组 ,而红细胞膜 IC花环率 ,血清中免疫粘附抑制因子活性及血清中 CIC含量较正常对照组明显升高。结论 :囊尾蚴病患者红细胞膜 C3b受体活性受损 ,清除 CIC能力下降。     

不同剂量复方吡喹酮治疗猪囊尾蚴病的形态学观察

应用不同剂量复方吡喹酮对人工感染猪囊尾蚴病猪治疗77天后,经光镜及电镜检查,其肌肉组织和脑组织中的囊尾蚴结构。结果表明,治疗剂量为20mg/kg组病猪体内囊尾蚴多数仍具有活力;治疗剂量为40、80、160mg/kg组病猪肌肉组织内的囊尾蚴全部死亡并被吸收,肌肉组织结构正常,脑组织内残留少量小钙化灶。     

Single parenchymal brain cysticercus: relationship between age of patients and evolutive stage of parasites

Abstract

Background: A recent hypothesis suggested that in many cases cysticercal granulomas represent recently established Taenia solium metacestodes rapidly destroyed by the host’s immune system. Here, we attempted to determine whether patients with cysticercal granulomas are younger than those with other forms of parenchymal brain cysticercosis.

Methods: Series of 185 patients with single parenchymal brain cysticercus, classified according to the stage of the parasite at the moment of diagnosis in cysts without inflammation, cysts with inflammation, granular lesions, and calcifications. We correlated the age of the patients with the parasite evolutive stage.

Results: Patients with cysticercus granulomas were significantly younger than those with vesicular cysts (17·7±12·9 versus 36·8±15·1 years, P<0·005) or calcifications (17·7±12·9 versus 40·8±19·7 years, P<0·0001). There was also a non-significant trend for patients with granulomas to be younger than those with coloidal cysts (17·7±12·9 versus 26·7±15·6 years, P?=?0·367).

Conclusions: Results from this study argued against the classical hypothesis that granulomas are the end result from long-established vesicular cysts destroyed by the host’s immune system. Vesicular (viable) cysticerci must be treated with cysticidal drugs as it is unlikely that they will be spontaneously destroyed.     

1266例不同类型脑囊尾蚴病患者血清囊虫IgG抗体检测结果分析

目的观察血清囊虫IgG抗体在脑囊尾蚴病临床诊断中的价值。方法对临床确诊的1 266例脑囊尾蚴病患者作血清囊虫IgG抗体检测,将检测结果进行分析。结果 1 266例脑囊尾蚴病患者阳性689例,阳性率54.42%。685例急性期患者中阳性436例,阳性率63.65%;476例慢性期患者中阳性173例,阳性率36.34%;两组间阳性率差异有非常显著性意义(x~2=84.0,P0.01)。520例急性期单发病灶患者阳性295例,阳性率56.73%,165例多发病灶患者阳性141例,阳性率85.45%,急性期单发灶与多发灶囊虫抗体阳性率差异有统计学意义(x~2=44.69,P0.01)。385例慢性期单发病灶患者阳性126例,阳性率32.73%,91例多发病灶患者阳性47例,阳性率51.65%,慢性期单发灶与多发灶囊虫抗体阳性率差异有非常性显著意义(x~2=11.46,P0.01)。混和期(急性期和慢性期病灶同时存在者)98例,阳性73例,阳性率74.49%;弥漫性(满天星病灶)患者7例,均为阳性。结论急性期脑囊尾蚴病抗体阳性率高于慢性期。急性期多发病灶者脑囊尾蚴病抗体阳性率高于急性期单发病灶者,慢性期多发病灶者脑囊尾蚴病抗体阳性率明显高于单发病灶者。     

脑室内猪囊虫病的CT和MR影像学诊断

报告经手术和病理证实的脑室内猪囊虫病３７例。ＣＴ轴位扫描均表现为脑室不对称性扩大，以囊虫所在的脑室扩大最为明显；增强扫描４例均无强化病灶；Ｉｓｏｖｉｓｔ脑室造影ＣＴ扫描２８例，２７例见脑室内球形低密度充盈缺损，１例导水管以上无占位性病变，导水管以下无造影剂。２例改变体位后复查ＣＴ扫描，充盈缺损病灶位置有改变。３例ＭＲ均表现为第四脑室扩大特别显著，第三脑室和双侧侧脑室扩大。对脑室内猪囊虫病的ＣＴ和ＭＲ影像学特点进行了讨论。     

用猪带绦虫可溶性虫卵抗原ELISA间接法诊断囊虫病的实验研究

用猪带绦虫可溶性虫卵抗原酶联免疫吸附试验（ＥＬＩＳＡ）间接法诊断囊虫病。检查囊虫病人１２０例，正常人３６例及其他病人６７例。囊虫病人阳性率为９０．８３％正常人及其他病人假阳性率分别为２．６１％及４．５６％，结果证明本法敏感特异。     

215倒人体猪囊虫病的临床与病理分析

本文报告215例人体猪囊虫病的临床与病理分析。男性149例(69.3％),女性66例(31.7％)。病理与临床诊断相符者仅95例(44.2％)。组织学上有三种改变。并对其中96例作免疫化学研究。认为本病与免疫反应有关。而不是虫体刺激引起的炎症反应。     

山东省囊虫病的危害及对经济影响的调查评价

目的：为探讨囊虫病的危害性及对社会经济的影响。方法：随机调查了150例囊虫病住院患者，对其造成的机体损害作了评价并对患者的直接和间接经济损失进行了量化研究，并评价全省因囊虫病猪所造成的经济损失。结果：住院患者中，脑囊虫病占97．33％，造成严重损害，如癫痫发作、高颅压等，给病人及家属精神和心理上造成伤害。患者年人均经济损失为6805元，最高者达37597元。人均直接损失5770元（84．8％）；间接损失1035元（15．2％）。直接经济损失占家庭年均纯收入的82．2％，最多为32912元，占家庭年纯收入的比例最高者达601％。误诊、误治率为34％，最高费用20000元。全省囊虫病患者年经济损失为23817．5万元，其中直接经济损失为20195万元，间接经济损失3622．5万元。全省猪囊虫病平均感染率为0．74％，平均每年检出囊虫病猪174420头，年直接经济损失为11564万元。全省因囊虫病而造成的总的经济损失为35381．5万元。结论：囊虫病不但对人体造成严重的危害，而且引起巨大的经济损失。