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31.
世界高等医学教育研究的现状和趋势及其借鉴 总被引:7,自引:0,他引:7
孙宝志 《中华医学教育杂志》2006,26(5):1-4
本文作者多年主持多项国际医学教育研究合作项目,多次参加国际性医学教育学术会议,根据文献资料和观察所见,介绍世界高等医学教育研究机构建立的沿革;高等医学教育研究得以发展的动因;高等医学教育研究的功能与任务;对提高医学教育教学质量的最佳途径的研究成果;世界各国开展的“医学教育硕士学位”培养计划,以及借鉴与对策。 相似文献
32.
M. Sibille N. Deigat V. Olagnier D. Vital Durand R. Levrat 《European journal of clinical pharmacology》1992,42(4):389-393
Summary All the clinical, laboratory and electrocardiographic adverse events detected during 24 Phase I studies in the same unit over a 5 y period are reported here. 430 healthy male volunteers were involved, corresponding to 5488 days of follow-up.The overall incidence of adverse events was 13.5%, with a significant difference between active drug (15.3%) and placebo (7.4%) treatments. There were 69 distinct types of adverse events. Headache was the most frequent symptom (2%). There were severe adverse events in 20 cases (0.36%), with an incidence of 20/430 per subject (4.6%). There were no deaths or life-threatening events.Although the main objective of Phase I studies is to determine the maximum dose tolerated, cause-effect relationships with adverse events are hard to establish, because of the frequency of adverse events with placebo, and because of the limited number of subjects included such studies. 相似文献
33.
34.
Atle Dyregrov 《Journal of traumatic stress》1997,10(4):589-605
Critical Incident Stress Debriefings have become an intervention method used in various cultures, countries and groups following critical incidents. Although the structure of such meetings has been adequately described, utilization of the group processes involved has received less attention. A model, process debriefing (PD), based on experiences from Europe, is presented. Some differences between the current CISD process in the United States and the Europe based model are outlined. Various factors that impact the process of debriefings are discussed with a special emphasis on leadership, and implications of these group process variables for psychological debriefing are presented. It is emphasized that the continued exploration and discussion of process issues is critical to advance the understanding of the critical elements of debriefing. 相似文献
35.
Droperidol (DROP) is used in the emergency department (ED) for sedation, analgesia, and its antiemetic effect. Its ED safety profile has not yet been reported in patients (pts). OBJECTIVES: To document the use of DROP in high-risk pts (those with head injury, alcohol or cocaine intoxication, and/or remote or recent seizures), and to determine the number of serious and minor adverse events (AEs)-seizures, hypotension, extrapyramidal side effects (EPSEs)-after DROP. METHODS: The ED database (EmSTAT) was queried to determine who received intramuscular or intravenous DROP in the ED in 1998; further chart review was done if the patient was considered high risk for or had experienced an AE. Multiple regression analysis using a random-effects model determined the significance of each variable in the occurrence of AEs. RESULTS: 2,468 patients (aged 20 months to 98 years; 112 < or =17 years; 141 > or =66 years) received DROP for agitation (n = 1,357), pain (1,135), anxiety (99), vomiting (173), or other reasons (50). There were 945 pts considered high risk; 933 charts were reviewed (DROP mean dose 4.1 +/- 2.0 mg); of these, 50 patient visits did not meet the criteria for high risk. There were 622 pts with head trauma (401 with alcohol use), including 47 with computed tomography (CT) scans positive for brain injury, 64 with cocaine use, and 197 with recent or remote seizures (137 with alcohol use). Minor AEs such as transient hypotension occurred in 96 pts after DROP (73 with alcohol use); 20 received intravenous fluids, while an additional 28 pts (8 with alcohol use) received rescue medications for EPSEs. Six possible serious AEs occurred in pts with serious comorbidities; 2 cases of respiratory depression, 3 post-DROP seizures, and 1 cardiac arrest (resuscitated) 11 hours after DROP in a cocaine-intoxicated pt (normal QT interval). There was no significant difference among high-risk groups in the occurrence of AEs. CONCLUSIONS: The vast majority of pts who received DROP in the ED did not experience an AE. A few serious AEs were noted following DROP in patients with serious comorbidities; it is not clear that DROP was causative. 相似文献
36.
I. M. Goodyer P. J. Cooper C. M. Vize L. Ashby 《Journal of child psychology and psychiatry, and allied disciplines》1993,34(7):1103-1115
Abstract— Interviews with parents of a non-referred sample of 11–16-year-old girls ( n = 82) revealed that a significantly greater proportion of mothers with a lifetime: history of any psychiatric disorder also reported one or more recent undesirable life events focused on the adolescent compared with mothers with no such history, Lifetime episodes of maternal depression and recent undesirable life events exerted significant additive effects on the likelihood of depression occurring in the previous 12 months in adolescent girls. Some families may be "life event prone" as a consequence of lifetime episodes of parental psychopathology. 相似文献
37.
Depressed pathological gamblers 总被引:1,自引:0,他引:1
Depressed gamblers (n = 14) were compared with normal controls (n = 41) for antecedent life events. The depressed gamblers had experienced significantly more life events, and undesirable or exit life events, during the 6 months before the onset of depression. 相似文献
38.
对部队汽车驾驶员203名的心身健康和行车安全的相关因素研究表明:驾驶员可发生心身障碍,尤其眼和耳、呼吸系统,骨胳肌肉系统及抑郁等为著。其影响因素,主要有负性精神紧张总值(-Lcu)、个性的精神质、神经质、掩饰性、内向倾向、开车公里数、开车年限及精神疾病家族史。某些心身问题、神经质、掩饰性较高、年龄偏大、开车公里数多及开车年限长等与事故差错的发生有关。 相似文献
39.
The Vaccine Safety Datalink (VSD) is a collaboration between the CDC and eight large HMOs to investigate adverse events following immunization through analyses of clinical data. We modified an existing system, called MediClass, that uses natural language processing to identify clinical events recorded in electronic medical records (EMRs). We customized MediClass so it could detect possible vaccine adverse events (VAEs) generally, and gastrointestinal-related VAEs in particular, in the text clinical notes of encounters recorded in the EMR of a large HMO. Compared to methods that use diagnosis and utilization codes assigned to encounters by clinicians and administrators, the MediClass system can both find more adverse events and improve the positive predictive value for detecting possible VAEs. 相似文献
40.
已婚育龄妇女避孕措施变化趋势分析 总被引:5,自引:1,他引:4
目的:了解已婚育龄妇女避孕措施的变化趋势,为指导计划生育服务工作提供科学依据。方法:收集1983~2005年苏州市已婚育龄妇女避孕方法的资料,并用统计软件对其变化趋势进行了分析。结果:已婚育龄妇女节育率在88.38%~92.94%范围波动,长效避孕措施现用率从75.19%下降至71.27%,而短效避孕措施从12.86%上升至17.11%。宫内节育器的现用率从50.09%上升到66.50%;避孕套从1.94%上升到14.21%;其他避孕方法的现用率均呈下降趋势,其中女性绝育现用率从24.42%下降到4.50%。结论:节育率维持在较高水平;长效避孕措施现用率下降而短效避孕措施现用率上升;避孕方法使用趋于多样化,需要提供满足个性化需求的指导和服务。 相似文献