青光眼滤过术后经角膜切口的人工晶体植入术

目的：介绍经角膜小切口的青光眼滤过术后的白内障现代囊外摘除和人工晶体植入的方法及产观察。方法：对２３例２３只眼施行手术，上方角膜缘内１ｍｍ处，做６－７ｍｍ弦长切口，信封式或连续环形撕囊，水力分核娩出，后房型人工晶体植入。结果：２３只眼术后视力全 膜散光为１．１３Ｄ；眼压术前术后对比，无统计学差异；术中术后无严重并发症。结论：经角膜小切口治疗青光眼滤过后的白内障能取得良好效果面无严重并发症。     

复性近视散光与单纯性近视的角膜地形图差异

目的探讨复性近视散光与单纯近视的角膜形态差异。方法近视88眼．分为复性近视散光组44眼，单纯近视组44眼，用角膜地形图仪检测角膜形态，并进行统计分析及组间比较。结果二组近视角膜前表面屈光力SlmK、ACP组间无差异（P＞0．05），角膜表面散光组间差异显著，有统计学意义（P＜0．01），角膜形态SRI、SAI值组间无显著差异（P＞0．05），复性组检影散光与角膜表面散光值无显著差异；角膜地形图类型在复性组以对称性蝴蝶结形和非对称性蝴蝶结形为主，单纯组则以规则圆结形和非对称性蝴蝶结形为主。结论角膜散光是复性近视散光与单纯近视之间角膜形态差异的主要原因。     

角膜地形图与散瞳验光散光差异分析

目的观察角膜地形图仪与散瞳验光测得的散光差异。方法以138眼（74例）近视眼为研究对象，角膜地形图仪记录角膜地形图形态、角膜屈光度、角膜散光度；散瞳后应用全自动电脑验光仪结合带状光检影及试镜．确定球镜度数、柱镜度数和轴位。所有数据用SigmaSTAT软件包进行统计学配对t检验。结果二组总的平均散光度，散瞳组为－1．21±0．9D，角膜地形图组为－1．37±0．63D，统计有显著性差异（P＜0．01）；总平均散光轴位：散瞳验光组为100．14°±76．4°，角膜地形图组为96．80°±78．0°，统计无显著性差异（P＞0．05）。结论　角膜地形图仪和散瞳验光记录的散光度有差异性，轴位无显著性差异，在设计屈光性手术时有指导意义。     

HSV (Type 1) infection of the trigeminal complex

Following corneal inoculation with herpes simplex virus (Type 1) (HSV), virus spreads to the CNS by axonal transport in the central branches of trigeminal ganglion cell neurons. Although this mode of viral entry to the CNS is rare for humans, it appears to be the principal route of entry into the CNS in animal models of herpetic corneal disease. In this study, the corneas of BALB/c mice were unilaterally inoculated with HSV, and the distribution of HSV-immunoreactive label was studied to identify the central branches of the axons of infected trigeminal ganglion cells. Virus was first noted in the brainstem trigeminal complex 4 days after corneal inoculation, when HSV-labeled afferents were found throughout the course of the descending tract of V as well as in interstitial neurons in the tract. By 5 days labeled neurons were also found not only in the n. caudalis and portions of the n. interpolaris of the trigeminal complex but also in laminae I–IV of the dorsal horn of the upper cervical levels of the spinal cord. No immunoreactivity was seen in other regions of the complex, including the n. oralis or the main sensory n. of V. By 6 days, however, the infection had spread to the main sensory division of V.     

眼睛手术术眼清洁准备方法的研究

目的　改变传统结膜囊冲洗方法存在的球结膜充血、角膜水肿、混浊、疼痛等弊端,使术眼结膜囊及周围皮肤的清洁准备达到手术要求,减轻或消除病人的痛苦。方法　对施行眼睛手术的6 0例病人随机分为2组,30例 组,采取2种术眼准备方法,观察眼睛局部反应和分析结膜囊微生物采样报告。结果　1 万升汞(二氯化汞)易导致结膜充血、畏光、流泪、角膜水肿、疼痛。结论　选用2mg ml庆大霉素溶液—碘伏的术眼准备方法,可保证术眼角膜和结膜的最小刺激性和无菌性,更符合术眼准备的要求,具有一定的临床应用及推广价值。     

白细胞介素—1拮抗剂治疗重度角膜烧伤初步疗效观察

目的：观察白细胞介素－１受体拮抗剂治疗重度角膜烧伤的效果，方法；采用ＩＬ－Ｉｒａ局部点眼法，或／和结膜下注射法治疗５例（５只眼），结果：观察２￣６个月，所有治疗眼视力均有增进，４只眼治愈遗留瘢痕，１只眼角膜混浊减轻，结论：临床资料显示ＩＬ－ｌｒａ对眼部炎症可能提供一种新的治疗途径。     

应用冷冻保存角膜行板层角膜移植实验及临床应用研究

报告应用冷冻保存的角膜，行板层角膜移植的动物实验及临床应用结果。对4只家兔应用冷冻保存3个月的角膜行板层角膜移植，术后3个月取兔角膜行光镜及电镜检查，发现植片与植床愈合良好，上皮层次清楚。临床应用15例病人，原发病均控制，植片透明愈合，无一例发生感染。     

儿童散光检测的比较分析

报告７０例（１４０只眼）儿童散光检测的情况。检查方法包括检影验光、电脑验光和角膜曲率计测量，分别得出眼散光（ｅｙｅ＇ｓａｓｔｉｇｍａｔｉｓｍ，ＥＡｓ）和角膜散光（ｋｅｒａｔｉｃａｓｔｉｇｍａｔｉｓｍ，ＫＡｓ）的数据。结果表明，三种方法检测的散光度及散光轴有很好的一致性；眼散光和角膜散光的关系式为ＥＡｓ＝０．９４ＫＡｓ－０．１３，与以往的研究结果一致。我们建议：为了使儿童散光检查准确可靠，有必要采用角膜曲率检查作为验光的辅助方法。     

Keratin films for ocular surface reconstruction: Evaluation of biocompatibility in an in-vivo model

Amniotic membrane (AM) transplantation is the clinical standard for ocular surface reconstruction, however recently keratin film (KF) has been proposed as an alternative material. Aim of the current study was to evaluate corneal biocompatibility of KF in a rabbit model. Forty-six New Zealand white rabbits underwent dissection of a corneal intrastromal pocket in which an AM or KF implant was inserted and observed for 10 days and for 4 weeks. Half of animals received topical steroids, while the other half were left without. At the end of the follow-up clinical and histology examinations were performed to evaluate transparency, inflammation and degradation. After 10 days the clinical and the histology results appeared to be comparable in KF implanted eyes treated with and without steroids. After 4 weeks, comparable clinical results were observed in all KF implanted eyes, while the inflammation score was lower in non-steroid compared to steroid treated eyes along with a higher degradation rate of the keratin films. In conclusion, keratin films from human hair show a good biocompatibility and transparency in vivo. The administration of topical steroids seems to slow down implant degradation which might be important for the modulation of tissue integration and matrix regeneration.