全文获取类型
收费全文 | 108篇 |
免费 | 7篇 |
专业分类
儿科学 | 2篇 |
妇产科学 | 2篇 |
基础医学 | 4篇 |
口腔科学 | 1篇 |
临床医学 | 9篇 |
内科学 | 34篇 |
神经病学 | 1篇 |
外科学 | 45篇 |
综合类 | 6篇 |
预防医学 | 6篇 |
药学 | 2篇 |
中国医学 | 2篇 |
肿瘤学 | 1篇 |
出版年
2023年 | 3篇 |
2022年 | 6篇 |
2021年 | 6篇 |
2020年 | 3篇 |
2019年 | 5篇 |
2018年 | 9篇 |
2017年 | 3篇 |
2016年 | 3篇 |
2015年 | 6篇 |
2014年 | 7篇 |
2013年 | 3篇 |
2012年 | 5篇 |
2011年 | 2篇 |
2010年 | 6篇 |
2009年 | 6篇 |
2008年 | 3篇 |
2007年 | 9篇 |
2006年 | 3篇 |
2005年 | 2篇 |
2004年 | 6篇 |
2003年 | 2篇 |
2002年 | 4篇 |
2001年 | 2篇 |
2000年 | 2篇 |
1999年 | 1篇 |
1997年 | 2篇 |
1996年 | 1篇 |
1995年 | 1篇 |
1992年 | 1篇 |
1989年 | 1篇 |
1987年 | 1篇 |
1979年 | 1篇 |
排序方式: 共有115条查询结果,搜索用时 15 毫秒
51.
Particle image velocimetry is used to study the flow field associated with off-design conditions of the 50cc Penn State Ventricular Assist Device. Phase average data, for 300 consecutive beats, was acquired for 60, 75, and 90 beats per minute (bpm) at 35/65 systolic duration and at 75 bpm for 50/50 systolic duration. Diastolic flow is dominated by the inflow jet and shows more penetration and better wall washing at higher beat rates and shorter diastolic time. A flow separation near the minor orifice of the aortic valve, however, is larger under these conditions. Turbulent energy, which peaks during diastole, is found to be strongest at the edges of the jet and near the valves and scales well with the maximum inlet jet velocity. A region of potential separation on the right lateral wall is identified and will be relieved by geometric modifications of the evolving design. 相似文献
52.
53.
Akira Saito Motomi Shiono Yukihiko Orime Shinya Yagi Kin-ichi Nakata Kunihiro Eda Tsutomu Hattori Michio Funahashi †Yoshiki Taniguchi Nanao Negishi Yukiyasu Sezai 《Artificial organs》2001,25(9):728-732
The left ventricular assist device (LVAD) with centrifugal pump has two characteristics. One is a pump flow wave of the centrifugal pump, consisting of the pulsatile flow of the native heart and the nonpulsatile flow of the centrifugal pump. The other is that the centrifugal pump fills from the native heart not only in the systolic phase, but also in the diastolic phase. In the case of the apex outlet LVAD with centrifugal pump, blood flows from the left atrium through the left ventricle to the pump. Pump flow is regulated by preload, and preload is regulated by diastolic hemodynamics. The aim of this study is to analyze the relationship between pump flow and the diastolic hemodynamics of the native heart. Ten anesthetized intact pigs were studied after placement of an LVAD. Data were recorded with the LVAD off (control) and the LVAD on. The assist rate was changed to 25%, 50%, and 75%. The indexes of left ventricular (LV) diastolic function included LV myocardial relaxation (time constant of isovolumic pressure decay [Tau] and maximum negative dP/dt [LV dP/dt min]) and LV filling (peak filling rate [PFR], time to peak filling rate [tPFR], and diastolic filling time [DFT]). Stroke volume decreased significantly in 75% assist. LV end-systolic pressure decreased significantly in 50% and 75% assist. LV end-diastolic volume decreased as assist rate increased, but there were no significant changes. Stroke work decreased significantly in 50% and 75% assist. LV dP/dt min decreased significantly in 50% and 75% assist. Tau prolonged as assist rate increased, but there were no significant changes. DFT shortened significantly in 75% assist. PFR increased significantly in 75% assist. tPFR shortened significantly in 50% and 75% assist. In this study, LV relaxation delayed as an increasing of pump assist rate, but it suggested a result of reduction of cardiac work. Also, it was suggested that LVAD increases the pressure difference between the left atrium and the left ventricle in the diastolic phase. This phenomenon is due to the filling of the left ventricle. In this study it was suggested that as pump assist rate increases, it is more effective to keep cardiac function in the diastolic phase. 相似文献
54.
55.
Roland Hetzer Yuguo Weng Evgenij V. Potapov Miralem Pasic Thorsten Drews Michael Jurmann Ewald Hennig Johannes Müller 《European journal of cardio-thoracic surgery》2004,25(6):263-970
Axial flow pumps have gained increased acceptance since their first clinical use in 1998. The present report summarizes the clinical experience with patients treated for severe cardiogenic shock for the first time with a newly developed axial flow pump with magnetically levitated bearings. Material and methods: The axial flow pump Incor was implanted in 24 patients between June 2002 and June 2003. All except one patient were men. In 16 patients dilative cardiomyopathy, in seven ischemic and in one restrictive cardiomypathy had been diagnosed. All patients presented with catecholamine-dependent end-stage heart failure, seven of them were on an artificial ventilator and three were dependent on intraaortic balloon pump support. All patients suffered from organ dysfunction resulting from low cardiac output. Results: There were no perioperative deaths. The 30-day mortality rate was 8% (n=2); 79% (n=19) of patients reached a condition to be discharged home. The cumulative time on the device is 6.9 years; the longest individual time up to July 1, 2003 is 12.6 months. There were no structural defects or failures of the system. In one case the controller had to be exchanged because of intermittent malfunction. Cardiac output ranged between 4 and 6 l in all instances and there were no cases of infection of the drive-line or the system. Hemolysis was present initially but was not detectable in the later course. There were three instances of transient ischemic attacks. Two patients developed late cardiac tamponade with re-opening of the chest after 9 and 14 days. In one patient persistent gastrointestinal bleeding required re-hospitalization and transfusion therapy. Two patients were weaned from the device after 6 and 7 months of support, respectively. Conclusion: The preliminary clinical experience with Incor is promising. The flow is sufficient for recovery from multiorgan failure and the pump allows long-term hemolysis-free support. The concept of magnetically levitated bearings has proven to be durable and reliable. In the case that the heart may recover through unloading, weaning from the pump is possible. 相似文献
56.
57.
Angiopoietin‐2 in acute myocardial infarction complicated by cardiogenic shock—a biomarker substudy of the IABP‐SHOCK II‐Trial 下载免费PDF全文
58.
Jasmin S. Hanke Sebastian V. Rojas Murat Avsar Axel Haverich Jan D. Schmitto 《Current Cardiology Reviews》2015,11(3):246-251
Nowadays, the worldwide number of left ventricular assist devices (LVADs) being implanted per year is higher than the number of cardiac transplantations. The rapid developments in the field of mechanical support are characterized by continuous miniaturization and enhanced performance of the pumps, providing increased device durability and a prolonged survival of the patients. The miniaturization process enabled minimally-invasive implantation methods, which are associated with generally benefitting the overall outcome of patients. Therefore, these new implantation strategies are considered the novel state of the art in LVAD surgery.In this paper we provide a comprehensive review on the existing literature on minimally-invasive techniques with an emphasis on the different implantation approaches and their individual surgical challenges. 相似文献
59.