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81.
Shimizu M Hirokawa M Manabe T 《Virchows Archiv : an international journal of pathology》1999,434(3):241-244
We report a case of a parasitic nodule of the thyroid in a patient with Graves’ disease, which mimicked a lymph node metastasis
from a primary occult thyroid carcinoma. The patient was a 67-year-old Japanese woman with a past history of subtotal thyroidectomy
for Graves’ disease, who was referred to our hospital because of a right cervical mass. A lymph node-like lesion measuring
1.5 cm in diameter was palpable, distinct from the remnant of the right thyroid lobe. Thyroid scintigraphy using 123I-Na revealed a hot lesion at the upper lateral portion of the right thyroid lobe, and this was resected. Microscopically,
the mass showed thyroid follicles with lymphocytic infiltration and lymphoid follicles. Clear ground glass nuclei, nuclear
grooving and intranuclear inclusions were not observed. No morphological evidence of the lymph node was found in the mass
by reticulin staining. Parasitic nodules of the thyroid in patients with Graves’ disease may mimic a metastatic carcinoma
of the thyroid.
Received: 21 January 1998 / Accepted: 15 April 1998 相似文献
82.
用蓖麻凝集素(RCA Ⅰ)对3、4、5、6、7、8个月和出生前人胚食管和食管癌组织采用ABC法进行了石蜡切片标记。结果发现,人胚食管上皮在8月前后,有较明显的分化过程。3-7月,RCA Ⅰ所识别的半乳糖残基仅出现在顶部细胞纤毛的膜上,8月起,食管上皮逐渐由纤毛型演变为非纤毛型,RCA Ⅰ染色中见到基底细胞向表面分化出RCA Ⅰ阳性细胞取代RCA Ⅰ阴性细胞。意味着胞膜上半乳糖残基的表现早于上皮细胞形态学的改变。食管癌细胞,RCA Ⅰ受体的分布和着色的深度都与正常细胞不同、染色加深,不仅在胞膜而且在胞浆,都呈现强的阳性反应。结果提示:蓖麻凝集素对食管上皮的发育、分化以及癌变的研究,是有价值的。 相似文献
83.
IntroductionThe term ectopic thyroid refers to the presence of thyroid tissue located far from its usual anatomic placement and with no vascular connection to the main gland. The presence of swelling in atypical locations is diagnostically differentiated from other pathologies like pleomorphic adenoma or carcinoma, inflammatory lesions like sialadenitis, neurogenic tumors, paraganglioma, fibrolipoma and lymphadenopaties of diverse etiologies.Presentation of caseHere we present the case of a submandibular ectopic thyroid in a 67 year old woman. She came to our attention for a left submandibular swelling. The anamnesis did not show related pathologies, as well as blood tests. Diagnostic image studies and a FNAC were performed. The mass was surgically removed and histopatology showed a follicular adenoma in the contest of the capsulated lesion.DiscussionIt is important to not underestimate these types of lesions and procede with hematochemical, instrumental tests and above all surgery that can eliminate any diagnostic uncertainty and on the whole be therapeutic.ConclusionIt should not be forgotten that ectopic thyroid tissue can be a site for adenoma or papillary carcinoma and thus any watch and wait strategy should be avoided. 相似文献
84.
Gulen Sezer Alptekin Erkul Sinan Erkul Ali hsan Parlar Ahmet ekirdeki 《Interactive Cardiovascular and Thoracic Surgery》2021,32(6):996
Pulmonary sequestration is defined as nonfunctioning lung tissue that is not in normal continuity with the tracheobronchial tree and that has a systemic arterial blood supply. Herein, we aimed to present a case of a 34-year-old male patient who had massive left-sided haemothorax on admission due to a giant intralobar pulmonary sequestration. An emergent repair was performed under cardiopulmonary bypass with axillofemoral cannulation. 相似文献
85.
William C. Roberts 《The American journal of cardiology》2018,121(11):1413-1435
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87.
摘要:癌症是一类遗传及表观遗传异常的复杂疾病。宫颈癌由癌前病变发展为侵入性的宫颈癌是由于人乳头瘤病毒(Human Papilloma Virus,HPV)持续感染引起了宿主基因组及表观遗传基因组的改变。表观遗传改变包括DNA甲基化水平改变、miRNA异常表达、癌基因的激活及抑癌基因沉默等。鉴于miRNA可被表观遗传机制调控,因而其在宫颈癌中的异常表达可能是启动子甲基化水平改变引起的。基于以上判断,本文对HPV感染、DNA甲基化水平改变及miRNA异常表达间的关系进行综述,以期揭示表观遗传异常与宫颈癌发生发展之间的关系。 相似文献
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