中医学对艾滋病病因病机的认识

中医学对于艾滋病的研究起始于中国援外医疗队对艾滋病患者的中药治疗,之后随着艾滋病在国内发病急骤升高,对人群健康和生命危害日益严重及社会对艾滋病的高度关注,中医学对艾滋病的研究广泛而深入.二十多年来,中医学对艾滋病的研究取得了显著成绩,而且显示出良好的前景.但是以往的研究重在临床症候观察及治疗药物的探讨,要实现"治本",重要的是从中医学角度认识其病因、病机等.     

β乐克治疗不稳定型心绞痛疗效观察

不稳定型心绞痛是介于稳定型心绞痛和急性心肌梗死之间的临床状态，是发生心脏事件的高危对象，故积极地治疗不稳定型心绞痛，对改善病人的预后有重要作用。近年来有报道用β乐克结合硝酸酯类扩冠药物治疗不稳定型心绞痛，能较好地缓解心绞痛症状。现将我院白2003年1月-2004年6月问共收治不稳定心绞痛66例采用β乐克结合常规药物治疗的临床效果总结如下。     

B超诊断联体双胎（颅部联胎）1例

1临床资料 患者33岁，孕26周，因子宫大小与妊娠月份不符，来我院就诊。     

氯雷他定（分散片）治疗慢性荨麻疹的临床试验观察

目的：观察氯雷他定(分散片)治疗慢性荨麻疹的疗效及安全性。方法：每日一次口服氯雷他定(分散片)10mg，连续用药2周。结果：1周有效率40％，2周有效率87．5％。结论：氯雷他定(分散片)治疗慢性荨麻疹的疗效明确，副作用少，安全性。     

鞘内注射吗啡加可乐定对切口痛大鼠脊髓背角蛋白激酶A催化亚单位表达的影响

Objective To observe the effect of intrathecal clonidine plus morphine on expression of protein kinase A (PKA) catalytic subunit in the spinal dorsal horn in a rat model of incisional pain. Methods Eighty male Sprague-Dawley rats were divided randomly into five groups: sham group, control group, pre-incisional morphine 2.5 μg group, pro-incisional clonidine 5 μg group and preincisional morphine 2.5 μg plus clonidine 5 lag group (n=16). lntrathecal catheter and the model of incisional pain were pro-duced according to Yaksh and Brennan's described method respectively. Changes of pain behavior were assessed by mechanical with-drawal threshold (MWT) and thermal withdrawal latency(TWL). The expressions of PKA catalytic subunit in the spinal dorsal horn were assessed by immunohistochemical method and western blotting analysis. Results Compared with sham group, MWT and TWL in control group were decreased significantly at 2 h after incision (P<0.01) and the number of positive cells and protein expression of PKA catalytic subunit in the spinal dorsal horn were increased significantly in control group (P<0.01). Compared with control group, MWT and TWL in pre-incision morphine 2 μg plus clonidine 5 lag group were increased significantly at 2 h after incision (P<0.01) and the number of positive cells and protein expression of PKA catalytic subunit in the spinal dorsal horn were decreased significantly in pre-incision morphine 2 μg plus clonidine 5 μg group (P<0.01). However, MWT, TWL and the number of positive cells and pro-tein expression of PKA catalytic subunit in the spinal dorsal horn changed with no statistical significance in pre-incisional morphine 2.5 μg group and pre-incisional clonidine 5 μg group compared with control group. Conclusion lntrathecal clonidine significantly enhances the antinociceptive effect of intrathecal morphine in a rat model of incisional pain, which might be associated with inhibi-tion of the increased expression of PKA catalytic subunit in spinal cord.     

2例大剂量肾上腺素复苏成功报告

病例1：男性患者，52岁，因剧烈心前区痛放射至左上肢3h来诊．既往有高血压、冠心病史．间断服用降压药。查体：神清，生命指征正常，ECG示：急性广泛前壁心机梗死。立即给予吸氧、舌下含服硝酸甘油0．5mg、肌肉注射度冷丁50mg、建立静脉通路。患者突然出现意识丧失、全身抽搐、呼吸及大动脉搏动消失．BP0／0kPa，心电监护示：心室颤动。立即行面罩给氧．同时胸外心脏按压，     

脑出血锥颅置管血肿引流术148例分析

我院自1994年3月-2005年3月对148例脑出血病人行锥颅置管血肿引流术，效果满意。报告如下。