浅谈社区卫生体系的建设

随着社会的发展与进步，社区卫生服务应运而生。社区卫生服务是以人群和基层作为着眼点，是医疗卫生服务与人群的第一级接触，其核心是初级卫生保健。发展社区卫生服务是一条既符合中国国情又遵循低成本、高效益原则的卫生事业发展之路。     

为妇儿健康保驾护航--深圳市龙岗区妇幼保健院发展纪实

坐落在深圳东部美丽的龙岗中心城11区的龙岗区妇幼保健院．是一个现代化的花园式的保健院。她的成长历程和发展速度可以说是一个神话．是一个奇迹。在全国数以百计的妇幼保健体系中．她只是个新兵。说她新，是因为与历史长达50年之久的其他省、市的保健院相比，她仅存在十几个春秋，年轻是她的资本，也是她打拼的动力；说她新，是因为在这样一个三甲、三乙医院林立的高水平行业内．她刚刚晋升为二甲医院．前面的路依然很漫长．需要更多的汗水和奉献．也会遇到更多的困难和艰辛．才能登上更高的台阶；     

力达霉素对神经胶质瘤细胞血管生成拟态的抑制及对细胞凋亡的影响

Objective To evaluate the in vitro effects of lidamycin upon vasculogenic mimicry and apoptosis induction in glioma cells. Methods Tube formation assay was performed to estimate the inhibitory effects of lidamycin upon vasculogenic mimicry in C6 and U87 glioma cells. The vasculogenic mimicry of glioma cells was photographed and enumerated. Annexin V-FITC/PI was used for determination of glioma cell apoptosis with flow cytometry. Results Vasculogenic mimicry assay indicated that 0. 1 nmol/L, 0. 5 nmol/L and 1 nmol/L lidamycin showed significant inhibition of vasculogenic mimicry in C6 and U87 cells. Comparing with C6 control group (14. 7 ± 1.2), 0. 1 nmol/L (12. 7 ± 0. 6), 0. 5 nmol/L (9. 0 ± 1.7) and 1 nmol/L (4. 7 ± 0. 6) lidamycin inhibited vasculogenic mimicry in C6 cells with statistical significances (P = 0. 013, P = 0. 005 and P = 0. 0002 respectively). Comparing with U87 control group (14.7±1.2), the vasculogenic mimicry of 0.1 nmol/L (10.0±2.0), 0.5 nmol/L (8.3±1.5) and 1 nmol/L lidamycin (4. 3±0. 6) treated U87 cells showed statistical significances (P =0. 025, P =0. 005 and P =0. 0009 respectively). The apoptotic ratios of same dosages lidamycin treated C6 cells and U87 cells showed a similar tendency as vaaculogenic mimicry inhibition (P < 0. 001). Lidamycin was more potent than neocarzinostatin in vasculogenic mimicry inhibition and apoptosis induction of C6 cells and U87 cells. Conclusion Lidamycin can inhibit vasculogenic mimicry and promote apotosis of glioma cells. Thus it is a promising drug in glioma treatment. Further researches on the therapeutic efficacy of enediyne antibiotics in glioma are needed.     

知柏地黄丸加维生素C引起闭经1例

1病例报告 女，36岁。因来月经前几天面部反复出现痤疮0．5a。皮肤科医生诊治为内分泌紊乱，给予：知柏地黄丸，1次6g，2次／d；加用维生素C片，1次2片，2次／d。2个月后，突然停经，来我院妇产科检查．患者自述服药之前月经一直正常且从未服用其他药物，身体状况良好。自从服用知柏地黄丸＋维生索C后，面部痤疮不再出现，但突然停经。经同位素科化验激索六项。基本接近正常水平，B超检查。官体正常、卵巢及输卵管也无异常。嘱其瞻用活血化瘀药也无意义，     

Effect of Cycloheximide on the Adaptive Response Induced by Low Dose Radiation

Human lymphocytes pre-exposed to 10 mGy or 50mGy of X-rays become less sensitive to subsequent large dose irradiation,exhibited lower rate of chromosome aberration than expected.This adaptive response could be inhibited by cycloheximide,a protein synthesis inhibitor for successive 2h period ranging from 0.5h before to 4h after the low dose exposure,indicating that the adaptive response was directly related with the protein synthesis.     

完善医疗保障体系构建和谐社会——访劳动和社会保障部副部长王东进

中国特色的医疗保障体系框架初步形成以保障大病风险为重点,以医疗保险制度为核心,合理确定不同缴费主体、缴费水平、保障标准和医疗服务范围相对应的多形式、多层次保障方式逐步完善完善医疗保障体系的重点问题:完善统账结合制度、解决退休人员医疗保障和资金支持等     

021 匙叶甘松对多柔比星诱导大鼠心脏损伤时的氧化损害和细胞异常的抑制作用

作者通过评价反映心脏功能的几项参数，研究了匙叶甘松Nardostachys jatamansi根茎提取物在多柔比星诱导大鼠心肌疾病过程中对心脏内抗氧化剂状态和保护心脏的作用。