发作性睡病2例报道

例1：患儿，女，7岁，小学二年级学生，因“反复阵发性睡眠1个月”入院。患1个月因同班一淘气男生打她几次，情绪波动较大后，出现阵发性睡眠，一天发作数次，每次数分钟到半小时，患儿呈入睡状，眼睑下垂，四肢无力，反应略慢，呼之即醒，无尿失禁、发热、幻觉、及猝倒，有时站立时思睡，双下肢略摇动，无跌倒，为进一步治疗，来本院住院。查体：心、肺、胰、四肢、神经系统均未见异常。辅助     

哮喘急性发作院前急救的综合护理

支气管哮喘表现为反复发作的喘息、呼吸困难、胸闷、咳嗽,多数患者可自行缓解或经治疗后缓解.但哮喘的急性发作起病急,病情变化快、复杂.     

喘乐宁悬液治疗小儿支气管哮喘临床疗效分析

目的探讨喘乐宁悬液治疗小儿支气管哮喘急性发作的临床疗效。方法将我院86例支气管哮喘急性发作患儿随机分成两组（对照组和治疗组），均给予抗感染等对症治疗。治疗组此基础上雾化吸入0．5％喘乐宁悬液，观察治疗前后临床症状的变化。结果干预结果显示，两组患儿总有效率比较，差异具有统计学意义（P〈0．05）。结论喘乐宁雾化吸入可迅速缓解哮喘急性发作，改善肺功能，值得临床推广和应用。     

急性心肌梗死病人健康教育需求调查

急性心肌梗死(AMI)的发病率逐年上升，病死率较高，且易反复发作。为提高病人的生活质量，除采取一般急救措施外．还应实施针对性的健康教育。为提高对AMI病人健康教育的质量，笔者对56例AMI病人进行了健康教育需求的调查并给予针对性健康教育。现报告如下。     

入睡期脊髓性肌阵挛1例

临床资料患者,女,10岁。近半年来患儿几乎每晚刚入睡时出现间歇性身体和四肢抖动,症状持续数分钟或30min左右可自行消失。不伴呼吸急促、口吐白沫、面色变化或眼球上翻等,发作时易被唤醒,清醒时抖动停止。无睡语症、睡行症或其他睡眠障碍,亦无癫、外伤等病史。白天学习、生活不受影响。家族中无类似患者。神     

丙酚增加小鼠对缺氧的耐受

目的观察异丙酚对缺氧小鼠的影响.方法采用常压耐缺氧法、断头法及结扎双侧颈总动脉法研究了异丙酚对缺氧小鼠的影响.结果与生理盐水组比较,异丙酚30、15和7.5mg@kg-1均能延长常压耐缺氧条件下小鼠的存活时间,延长断头小鼠的呼吸时间,降低急性脑缺血小鼠2 h内的死亡率,其中30和15 mg@kg-1组与生理盐水组相比差异有显著性(P＜0.05或0.01).结论异丙酚对小鼠脑缺氧有保护作用.     

Feasibility of establishing cerebral ischemia models by using aerocyst-blocking bilateral ascending pharyngeal artery of piglets Imaging assessment

BACKGROUND: The cerebral ischemia and ischemia/reperfusion animal models are used to simulate the human cerebrovascular diseases is one of the popular topics of neurological science recently. To study the pathophysiology, pathogenesis, prophylaxis and treatment of ischemic cerebrovascular diseases and to establish the ideal animal model that is the most similar to the human cerebral ischemia, are the topics that the people generally cared about. OBJECTIVE: To evaluate the effects of aerocyst-blocking bilateral ascending pharyngeal artery on the establishment of cerebral ischemia models by using digital subtraction angiography (DSA), magnetic resonance diffusion-weighted imaging (DWI) and magnetic resonance perfusion-weighted imaging (PWI). DESIGN: Repetitive measure animal experiment. SETTING: Zhongshan Hospital Affiliated to Dalian University. MATERIALS: The experiment was carried out in the Animal Laboratory (Provincial Laboratory), Zhongshan Hospital of Dalian Univeristy from January to May 2006. A total of 14 domestic piglets, of 6 months old, weighing 12–15 kg, of either gender, were selected from Animal Experimental Center, Dalian University. Multistar T.O.P digital subtraction angiography machine was provided by Siemens Company, German. METHODS: Aerocyst-blocking bilateral ascending pharyngeal artery was used to establish cerebral ischemia models. And then, Multistar T.O.P. DSA was used for imaging of cerebral vessels before blocking, during blocking and at 0.5 and 2 hours after ischemia perfusion. GE Signa 1.5 T supraconduction magnetic resonance imaging was used for DWI examination; in addition, PWI was used based on focal sites and areas. Otherwise, magnetic resonance imaging (MRI) was used to detect signal changes of T1WI and T2WI in ischemic areas. MAIN OUTCOME MEASURES: Analytic results of DSA, DWI, PWI and MRI. RESULTS: All 14 experimental piglets were involved in the final analysis. ① DSA: The blood flow of bilateral ascending pharyngeal arteries and its branch were blocked at blocking phase, which restored 0.5 and 2 hours after reperfusion. ② DWI and PWI: There were no observable abnormalities in PWI and DWI at pre-blocking. Abnormal increased signals were found on both DWI and PWI at during and post-blocking. There were reduction in ADC and rCBF and delay in rTTP at all time points except pre-blocking. ③ MRI: There were no abnormal signals observable at any time of pre- and post-blocking in T1WI and T2WI. CONCLUSION: It is feasible to establish this kind of animal experimental models, and it can simulate the ischemic state; meanwhile, the existence and extent can be showed directly by DSA, DWI, and PWI.     

卒中和心脏病发作入院与寒冷有关

据J Clin Epidemiol报道，一项对17个国家的人院研究显示，天气寒冷可增加50岁以下妇女因卒中或心脏病发作人院的人数。     

桂枝汤加减治中风半身汗出38例

中风患者由于阴阳失调腠理不固，通常易出现半身汗出，且易反复发作，缠绵难愈。近年来，我科用桂枝汤加减治中风半身汗出38例，疗效满意，现报道如下。其中女12例，男26例，年龄51～76岁，自中风后便出现患侧半身汗出，既往无半身汗出病史，服用谷维素治疗效果不佳。     

神经肽Orexin与精神疾病

本文就神经肽Orexin分子生物学，促觉醒作用及与某些精神疾病的关系研究最新进展作一综述。