泮托拉唑钠维生素K3治疗胆汁反流性胃炎探讨（附60例临床分析）

我院自2005年4月至2007年3月对60例胆汁反流性胃炎的患者，采用泮托拉唑钠肠溶维生素K3治疗，取得显著疗效，现报告如下。     

门控心肌灌注显像对冠心病PCI后疗效评价

目的利用门控心肌灌注显像评价PCI的疗效。方法35例患者PCI术前1周及术后1～6个月均行门控心肌灌注显像,比较PCI前后血流灌注、室壁运动变化、LVEF的变化情况。结果冠心病患者PCI术后大部分患者的左室功能及血流灌注情况有明显的改善。结论门控心肌灌注显像在评价PCI手术的疗效方面有重要价值。     

升主动脉成形术中期效果分析

Objective Reduction ascending aortoplasty is an alternative procdure to the replacement of the ascending aorts in case of ascending aorta dilation. However,its applicabikity is still under debate.This retrospective study was designed to evaluuate the midterm follow-up of unsupported ascending reduction aortoplasty for of the ascending aorta in petients with aortic valve dis- ease.Methods From October ,1996 to April,2007, a total of 54 patients with aortic valve disease and dilatation of the ascending aorta underwent unsupported reduction aortoplasty in combination with aortic valve replacement at our institution The diameter of the ascending aorta was measyred before and early after sugery and then later between 13 and 96 menths [mean (23 ±16)months] posto- perativeiy using echocardiography.Results Two patients were dead with thean overall perioperative mortality rate was of 3.7%. The reduction aortoplasty decreased the diameter of the aorta from (45.77±6.02) mm p～eope～afive]y to (34.67 ～4.81) mm early after surgery (P<0.01). During follow-up, the diameter d aorta increased from (34.67±4.81) mm early after surgery to (37.65± 6.35) mm after a mean follow-up of (23±16) months (P<0.01), including the diameters are greater than > 45 mm within 5 pa- tients. Aortic stenosis and an early postoperative diameter greater than 40 mm m'e independent risk factors for redilatation. Conchusion Because of the unsatisfied midterm follow-up redilation of unsupported reduction aortoplasty for dilation of the ascending aorta with aortic valve disease, this group of patients needs continued intimate fallow-up or even reoperation. The patients of stenosis is the surtable indication for RAA, and it is necessary to reduce the diameter of aorta to be lees than 40 mm to prevent redilation.     

云南白药联合莫沙必利、奥美拉唑治疗反流性食管炎

反流性食管炎是由于下食管括约肌运动障碍或胃食管连接部结构异常,胃十二指肠内容物反流入食管,引起食管黏膜的化学炎症,主要临床表现为:反酸、反食、烧心、胸痛、吞咽困难及咽喉症状.     

阿斯利康公司产品Nexium在欧洲获得批准用于治疗儿童胃食管反流病

阿斯利康公司开发的产品埃索美拉唑 (商品名:Nexium)于2007年12月29日获得瑞典医药产品委员会批准,用于治疗儿童胃食管反流病(GERD).Nexium专为儿童患者设计,可通过鼻腔和胃管给药,它将成为第一个用于治疗儿童GERD的质子泵抑制剂.     

采用发光细菌研究探讨“十八反”配伍药物的临床毒性

历代对中药“十八反”配伍看法不一，近年来在动物实验和临床研究亦甚多，结果各抒已见，在此基础上我们运用了“明亮发光杆菌５０２测定”“十八反”药物的毒性，研究结果支持“十八反”配伍毒性并不增加，相反有些毒性有所降低的结论。     

前列腺素E_1致交界性逸搏心律1例

患者女性,72岁,因阵发性心前区疼痛一天,疑诊急性心肌梗塞于1996年5月3日急诊入院。查体:体温36.2℃,脉搏92次/min呼吸21次/min,血压18/12kPa。急性病容,自动体位,双肺呼吸音清晰,心界向左扩大,心率92次/min,心律齐,心音低钝,A_2>P_2,心脏各瓣膜区均未闻及病理性杂音。腹软肝脾均未触及.双下肢无水肿,神经系统检查:生理反射存在,病理反射均未引出。     

小儿经皮球囊法肺动脉瓣成形术的麻醉处理

采用骶管阻滞配合小剂量静脉麻醉药，应用于２３例经皮球囊法肺动脉瓣成形术（ＰＢＰＶ）的患儿。麻醉管理：（１）在完善骶管阻滞的基础上依靠术前药及小剂量静脉麻醉药。既可保证术中无痛，又可保持良好呼吸循环代偿功能，避免麻醉并发症发生；（２）除监测生命体征外，还应重点连续监测血压及ＳｐＯ２；（３）强调保证充足的有效循环血量的重要性。     

动脉粥样硬化的实验研究 Ⅳ动脉粥样硬化家兔主动脉平滑肌细胞…

探讨动脉粥样硬化家兔主动脉平滑肌细胞增殖与血小板胞浆游离钙水平、血小板聚集性变化的关系。发现高脂血症家兔主动脉平滑肌细胞较正常平滑肌细胞增殖明显增强。经高脂血清孵育的平滑肌细胞增殖增强。此外高血脂动物的血小板胞浆游离钙水平与聚集性也增强，提示高脂血清及血小板释放ＰＤＧＦ增多可能是刺激平滑肌细胞增殖的原因。用具有降脂作用的中药有效成分８５０１处理的家兔主动脉平滑肌细胞和用８５０１处理的家兔血清孵育后