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橄榄油对单核吞噬细胞系统的影响 总被引:1,自引:0,他引:1
本文采用橄榄油皮下注射、观察其对小鼠腹腔单核吞噬细胞的游出、活化及吞噬功能。结果发现、橄榄油对上述功能均有明显的抑制作。 相似文献
3.
Eunil Lee Eunha Oh Joohyun Lee Donggeun Sul Juneyoung Lee 《Toxicological sciences》2004,81(1):121-132
The Comet assay has gained increasing popularity for use in human biomonitoring or epidemiologic studies; however, one of the shortcomings of the Comet assay is a lack of agreement on a single appropriate Comet parameter that is capable of adequately describing observed DNA damages. Among the tail parameters of Comet features, the most frequently used are the tail moments (both the Olive tail moment and the extent tail moment), the tail DNA, and the tail length. Some studies comparing Comet parameters have been found in cell toxicity research, but there are few comparative studies that use human biomonitoring or epidemiologic data. In this study, we evaluate those four tail parameters in both high and low DNA damaged cells with the use of epidemiologic data. To do this, a new graphical approach, the so-called quantile dispersion graphs (QDGs) are used. In a comparison of an exposed group and a control group, either the tail moment or tail DNA is preferable to the tail length. With respect to providing smaller variability in quantiles for the amount of DNA damage, however, the tail moment is the preferred parameter for both groups. Moreover, the tail moment provides the most stable estimates for DNA damage because it has a larger degree of uniformity in quantile dispersions. To study high degrees of damage from toxic exposure using B cells or G cells, however, the tail DNA showed more significant discrepancies than the other parameters, in terms of both the mean differences and the graphical differences between the two groups. In view of this result, it is suggested that both the tail moment and the tail DNA be presented as tail parameters in human biomonitoring studies. 相似文献
4.
高恒妙 《中国小儿急救医学》2015,(2)
作为肠外营养的重要组成部分,脂肪乳剂具有避免必需脂肪酸缺乏和作为高密度能量来源的作用。选择脂肪乳剂非常复杂,主要是因为不同的脂肪乳剂由不同的脂肪酸构成,可通过不同途径改变机体的免疫反应。同时其生物化学特性不同,对炎症反应有明显影响。应依据患者的代谢状态选择脂肪酸的类型和脂肪乳剂的供给量。越来越多的证据提示,对处于高代谢状态的危重患者,应避免使用以大豆油为原料的标准脂肪乳剂,而选择含中链甘油三酯、橄榄油或鱼油的脂肪乳剂,以减少具有促进炎症反应和免疫抑制作用的ω-6多不饱和脂肪酸的比例。尽管目前证据尚不足以作出对某种脂肪乳剂的特殊推荐意见,但作为二十碳五烯酸和二十二碳六烯酸的来源,含鱼油的脂肪乳剂能更好地调节免疫反应,对减少危重患者住ICU时间有重要作用。 相似文献
5.
A new and rapid approach for analysis of olive oil has been developed using sorptive tape-like extraction in combination with laser desorption ionization mass spectrometry (STELDI-MS). This powerful combination has some great advantages, as no-separation steps, solvent-free, matrix-free, and no sample preparation. The olive oil compounds are analyzed by LDI-MS, directly from the sample spot in a thin-layer chromatography (TLC) plate. Chosen samples represent products commonly used as adulterants in extra virgin olive oil (EVOO) and the main monitored ions were lipid adulteration markers. Analytical procedures consisted of profiling the main fatty acids (m/z 255 – palmitic acid, 279 – linoleic acid, 281 – oleic acid and 283 – stearic acid), triacylglycerols (m/z 901 – LLL and 907 – OOO) and some phenolic compounds (m/z 169 – gallic acid, 193 – ferulic acid and 195 – 2(4-hydroxyphenyl) ethyl acetate) in extra virgin olive oil (EVOO), olive oil (OO), hazelnut oil (HO) and soybean oil (SO). Compound identification was confirmed by analysis of collision-induced dissociation (CID) products in positive (ion [M+Na]+) and negative mode (ion [M−H]−). This method is simple, fast and efficient in identifying compounds that can be used to recognize different levels of adulteration, oxidation and hydrolysis of vegetables oils. 相似文献
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Hernández R Martínez-Lara E Cañuelo A del Moral ML Blanco S Siles E Jiménez A Pedrosa JA Peinado MA 《World journal of gastroenterology : WJG》2005,11(47):7480-7485
AIM: To analyze the relationship between perisinusoidal stellate cell (PSC) activation and the dietary fat quantity and composition in the treatment of hepatic steatosis. METHODS: Using an experimental rat model of steatosis based on the intake of a hyperlipidic diet (14% fat as olive oil or sunflower oil, HL-O and HL-S, respectively), we analyzed the liver's capability of recovery after the treatment with a normal-lipidic diet (5% fat as olive oil or sunflower oil, NL-O and NL-S, respectively) by immu-nocytochemical and Western blot analysis of glial fibril-lary acidic protein (GFAP) expression in PSCs, collagen quantification and serum aminotransferase determination. RESULTS: The fatty infiltration in the steatotic livers decreased after the treatment with both NL diets, indicating liver recovery. This decrease was accompanied with a lower collagen deposition and aminotransferase level as well as changes in the PSC population that increased the GFAP expression. The above-mentioned effects were more pronounced in animals fed on NL-O based diet. CONCLUSION: Treatment with a balanced diet enriched in olive oil contributes to the liver recovery from a steatotic process. The PSC phenotype is a marker of this hepatic-recovery model. 相似文献
8.
Reda Elkacmi Otmane Boudouch Aziz Hasib Mustapha Bouzaid Mounir Bennajah 《Sustainable Chemistry and Pharmacy》2020
Over the years, olive mill wastewater (OMW), which is generated from olive oil production has attracted considerable attention as one of the most polluted wastewaters due to its high concentrations of toxic compounds. It is a truism nowadays to guide research towards a novel and efficient technologies in order to treat this hazardous waste.In this paper, detoxification of OMW in an external loop airlift reactor (ALR) by electrocoagulation (EC) powered by photovoltaic solar system as a renewable and sustainable energy source was investigated. The effects of the operating parameters, such as electrolysis time, initial pH, current density (CD), and the axial position of the electrode were studied in continuous flow with two aluminum electrodes. A rate of abatement of about 79.24% for COD, 94.82% for polyphenols and 97.87% for dark color was observed within 40 min of treatment at 32.14 mA/cm2 current density, a position of the electrodes at 35 cm from the bottom of the riser compartment, and initial pH of 5.6. Furthermore, under these optimal conditions, the power supplied by photovoltaic cells led to amount of electrode dissolved (ELC) and specific energy consumption (SEC) of around 0.1118 kg/m3 and 9.86 kWh/m3, respectively. It has been proven that the EC treatment of OMW in ALR coupled with renewable energy source offers a low operation cost (0.2 USD/m3) compared to other treatment processes. 相似文献
9.
Zeynep Sumer Gulay Yildirim Haldun Sumer Sahin Yildirim 《African journal of traditional, complementary, and alternative medicines》2013,10(4):137-143
The mixture of olive oil and lime cream has been traditionally used to treat external burns in the region of Hatay/Antakya and middle Anatolia. Olive oil and lime cream have been employed by many physicians to treat many ailments in the past. A limited number of studies have shown the antibacterial effect of olive oil and that it does not have any toxic effect on the skin. But we did not find any reported studies on the mixture of olive oil and lime cream. The aim of this paper is to investigate the cytotoxic and antibacterial activity of olive oil and lime cream individually or/and in combination in vitro conditions, by using disk-diffusion method and in cell culture. The main purpose in using this mixture is usually to clear burns without a trace. Agar overlay, MTT (Cytotoxicity assay) and antibacterial susceptibility tests were used to investigate the cytotoxic and antibacterial activity of olive oil and lime cream. We found that lime cream has an antibacterial activity but also cytotoxic on the fibroblasts. On the other hand olive oil has limited or no antibacterial effect and it has little or no cytotoxic on the fibroblasts. When we combined lime cream and olive oil, olive oil reduced its cytotoxic impact. These results suggest that mixture of olive oil and lime cream is not cytotoxic and has antimicrobial activity. 相似文献
10.
Christine H. Holschneider Daniel G. Petereit Christina Chu I-Chow Hsu Yevgeniya J. Ioffe Ann H. Klopp Bhavana Pothuri Lee-may Chen Catheryn Yashar 《Brachytherapy》2019,18(2):123-132
Brachytherapy is well-established as an integral component in the standard of care for treatment of patients receiving primary radiotherapy for cervical cancer. A decline in brachytherapy has been associated with negative impacts on survival in the era of modern EBRT techniques. Conformal external beam therapies such intensity modulated radiation therapy (IMRT) or stereotactic body radiation therapy (SBRT) should not be used as alternatives to brachytherapy in patients undergoing primary curative-intent radiation therapy for cervical cancer. Computed tomography or magnetic resonance image-guided adaptive brachytherapy is evolving as the preferred brachytherapy method. With careful care coordination EBRT and brachytherapy can be successfully delivered at different treatment centers without compromising treatment time and outcome in areas where access to brachytherapy maybe limited. 相似文献