猕猴桃中药复方制剂对血清SOD及MDA含量的影响

猕猴桃中药复方制剂系采用猕猴桃汁为基质，配加绞股蓝、丹参等中药的有效成分制成。为了研究它的保健作用，在６３例５０岁以上、无急性疾病的中、老年人，３６例３０～４９岁健康的青年，３２例１４～１７岁健康的少年中进行试验，１０ｍｌ每日２次连续服用３０天后，中老年人血液ＳＯＤ显著增高，７０岁以上老人平均增高２．８倍，血清ＭＤＡ明显下降，７０岁以上平均下降８７．５％。     

Flow karyotypes and chromosomal DNA contents of genus Triticum species and rye (Secale cereale)

The flow cytometry and chromosome imaging method were jointly used for analyzing genome content and chromosomal DNA content of hexaploid wheat (AABBDD), hexaploid triticale (AABBRR), tetraploid wheat (AABB), and AA, BB, DD genome donors and RR genome rye. Their genome sizes were 34.4 pg, 40.9 pg, 26.2 pg, 12.1 pg, 13.7 pg, 10.5 pg, and 16.9 pg, respectively. The 2C nuclear DNA content of BB genome donor with 13.7 pg was the highest value among the other genome donors, AA or DD. The genome content of tetraploid wheat, unlike hexaploid wheat or hexaploid triticale, was larger than the sum of the genomes of AA and BB genome donors. The DNA content of each chromosome ranged from 1.22 pg in DD genome donor to 2.61 pg in rye. Each chromosome peak was divided into three to four groups. Only one chromosome was included in the highest chromosomal DNA peak in hexaploid wheat, tetraploid wheat, DD genome donor and rye but two chromosomes in AA, BB genome donors, and hexaploid triticale. Correlation between 2C nuclear DNA content and chromosome density volume was the highest value compared with the other chromosomal parameters of chromosome area, or chromosome length.     

1%线状透明颤菌面霜在中国女性敏感性皮肤的功效与耐受性评价

目的评价温泉浮游生物纯提取物(pureextractthermalplankton,PETP)即线状透明颤菌(Vitreoscillafiliformis,VF)提取物用于中国女性敏感性皮肤的功效与耐受性。方法经临床检查和乳酸刺激实验筛选出伴有敏感性皮肤的健康女性36例。早晚清洁面部后,均匀涂抹1%VF面霜,每日2次,连续使用3周。分别于实验前后由同一个皮肤科医师观察受试者的皮肤乳酸刺激分数,以及皮肤的临床表现(干燥、红斑、鳞屑、弹性、光滑度)。同时,检测皮肤颜色及皮肤角质层水合度等皮肤生物学参数。结果受试者的乳酸刺激分数显著降低,使用前后差异显著(P<0.0001)。干燥、红斑、鳞屑、光滑度均有不同程度改善。受试者对VF面霜耐受良好。结论伴有敏感性皮肤的中国女性,在皮肤日常护理中,使用含有VF提取物的护肤品有助于改善皮肤的敏感状态和皮肤保健。     

Inhibition of IgE formation in mice by glycoproteins from corn silk

The inhibitory effects of glycoproteins separated from a hot water extract of corn silk (U-CSE) on the formation of IgE antibodies after primarily and secondarily challenged responses with dinitrophenyl (DNP)-ovalbumin (OVA) antigen in mice were investigated using the passive cutaneous anaphylaxis (PCA) test. When U-CSE was given intranasally or intraperitoneally the day before primary immunization, IgE antibody production was strongly inhibited. Furthermore, it was found that new formation of IgE antibodies was readily inhibited by U-CSE administration in mice with high levels of IgE after primary immunization. It was also found that U-CSE markedly suppressed IgE antibody formation in secondarily challenged responses with the antigen. U-CSE may be clinically applicable to type I allergic diseases.     

Age at symptom onset and distribution by sex and symptoms in patients sensitized to different allergens

The aim of our study was to analyze the clinical features, particularly the age at symptom onset, of allergic subjects (asthma and/or rhinitis) on the basis of the etiologic elements (sensitization to various allergens). We identified a group of monosensitized patients and a group of polysensitized patients. Within these groups, we identified subgroups of subjects monosensitized to one of the five main allergenic mixes (mites, Gramineae, trees, Parietaria, and Artemisia) and five subgroups of patients sensitized nonexclusively, that is, polysensitized, to the same allergens. The comparison between the two groups and among the various subgroups enabled us to conclude that:

• 1)

  mono- and polysensitized patients present some clinical features so different as to constitute two clearly distinct clinical groups
• 2)

  analysis of the clinical features associated with the sensitization to a specific allergen brings us to significantly different conclusions when we consider subgroups of monosensitized or polysensitized patients
• 3)

  the parameter "age at symptom onset" shows great heterogeneity among both the mono- and the polysensitized subgroups - in particular, the great differences in mean age among the monosensitized subgroups (trees>y4rtemi.s(fl>Pflrie/flria>Gramineae>mites) appear very interesting and are open to various interpretative hypotheses
• 4)

  unlike the polysensitized group, in the monosensitized group and subgroups, mean age is similar between men and women and, only for tree- and parietaria -monosensitive patients, also between asthmatic and rhinitic subjects.

     

粉被虫草提取物对巨噬细胞吞噬功能及CTL活性的影响

研究粉被虫草菌丝体提取物在体外对小鼠腹腔巨噬细胞吞噬功能和脾细胞免疫功能的影响，结果表明：粉被虫草提取物在正常情况下不仅能够促进小鼠腹腔巨噬细胞的吞噬功能，而在免疫抑制的情况下，一定浓度的粉被虫草菌丝体提取物还能恢复提高吞噬功能；它不仅能促进正常脾活化Ｔ细胞的增殖，而且能恢复环磷酰胺和氢化可的松抑制免疫小鼠脾活化Ｔ细胞的增殖；在较高浓度下能增高小鼠脾细胞毒Ｔ淋巴细胞（ＣＴＬ）活性，同时在一定浓度下能恢复免疫抑制小鼠脾ＣＴＬ活性。     

龙眼参提取物对耐药口腔上皮样癌细胞株KB／MIT及耐药乳腺癌细胞株MCF-7／ADR的逆转作用

目的：研究龙眼参提取物XCKB／MIT细胞及MCF-7／ADR细胞株的耐药逆转作用。方法：设计4个不同浓度的龙眼参提取物组，采用MTT方法．测定体外培养的阿霉素敏感株MCF-7及其耐药株MCF-7／ADR以及米托蒽醌敏感株KB及其耐药株KB／MIT的IC50。结果：MCF-7／ADR耐药株及KB／MIT耐药株在龙眼参提取物与阿霉素或米托蒽醌的联合用药中其IC50值分别接近于单独用约于敏感株MCF-7和KB的水平．而与单独用药于耐药株其IC50有显著性差异。结论：龙眼参提取物可以逆转MCF7／ADR和KB／MIT的耐药性。     

Significance of sampling height of airborne particles for aerobiological information

Pollen and spore counts from Burkard traps for routine pollen and spore sampling placed at 15 m above ground and at ground level were compared. Daily counts of most pollen types were higher on the ground than at roof level, but the counts were significantly correlated. The ratios of pollen frequencies at high and low levels varied between 1.0 and 11.5. The most prominent differences were recorded for herbaceous pollen (e.g. Artemisia counts 11.5 and Poaccae counts 4.4 times higher at ground level) and in Botrytis and Ustilaginales spores. Tree pollen grains and basidiomycetous spores were more equally distributed. Wind speed did not affect the variation of pollen frequencies at either height. Large spores are not so unevenly distributed as previously supposed. Artemisia and grass pollen was detected 1 to 2 weeks earlier at ground level than on the roof. It is therefore concluded that especially the beginning of flowering should be monitored at a low level.     

苏乐康等抑制细胞转化能力及其机制的探讨

研究了苏乐康、绿茶提取物对~(60)钴γ射线和雌性激素联合诱发叙利亚金黄地鼠胚胎细胞恶性转化的抑制能力,并用脉冲辐解技术,对其抑制机制进行初步探讨。实验结果表明,苏乐康、绿茶提取物对γ射线和雌性激素联合诱发的金黄地鼠胚胎细胞恶性转化的抑制率分别为70.15％(P<0.05)和81.59％(P<0.05),它们的这种抑制能力与其清除超氧阴离子的能力有关,