分散与集中管理对医疗器械清洗与包装质量的效果分析

目的 观察分散与集中管理对复用医疗器械清洗和包装质量效果的影响.方法 对全院复用医疗器械分别采用各科室分散管理和供应中心集中管理,评价器械的清洗和包装质量,比较两种管理模式下复用医疗器械包的器械清洗质量、器械功能完好性、包布完好性及清洁质量、包内指示卡、包外标签等质量指标.结果 集中管理后复用医疗器械的清洗和包装质量整体合格率为99.3％,明显高于分散管理的85.6％,差异有统计学意义(P＜0.01).结论 复用医疗器械由消毒供应中心进行集中管理,能有效提高器械的清洗和包装质量,可降低医院感染风险,利于医院感染控制.     

重度吸入性损伤的救治体会

目的　总结３０ 例重度吸入性损伤的治疗经验与失败教训。方法　从治愈与死亡病例中回顾与总结重度吸入性损伤的治疗经验。如：诊断明确即行气管切开、吸氧治疗，气道冲洗清除气道分泌物；皮质激素短期用于肺水肿或严重支气管痉挛时，鼓励病人咳嗽、深呼吸、翻身拍背、体位引流等。结果　本组３０ 例中治愈１４ 例，治愈率为４６－６％ ，死亡１６ 例，病死率为５３－３％ 。结论抓早、抓好各项治疗措施，重视并发症的防治，可提高此类病人的治愈率     

可调式牙冠形态试件厚度控制仪的研制

目的:为能够严格控制牙冠形态试件各层结构尺寸的准确、均匀一致,设计出精度高、使用方便的可调式牙冠形态试件厚度控制仪.方法:利用AUTO CAD软件分析构图,我们自行研制了可调式牙冠形态试件厚度控制仪,用于牙冠形试件的核基底层蜡型制作、饰面层堆瓷过程中的厚度调控.应用此仪器制作0.75、1.00、1.20 mm等3种厚度的蜡型试件,将完成的试件从咬合面垂直切开,千分尺随机测量试件咬合面与轴壁厚度.结果:蜡型厚度误差为0.01 mm,同组蜡型的咬合面及轴壁各测试点之间的数值无显著差异(P＞0.05).结论:该仪器设计科学合理,结果准确可靠,试件加工重复性好,咬合面厚度与轴壁厚度均与所设计的理论厚度相符且均匀一致,能够满足口腔牙冠修复材料实验的测试要求.     

Golgi apparatus and neurodegenerative diseases

Neurodegenerative disorders are typically characterized by progressive and extensive neuronal loss in specific populations of neurons and brain areas which lead to the observed clinical manifestations. Despite the recent advances in molecular neuroscience, the subcellular bases such as Golgi apparatus (GA) for most neurodegenerative diseases are poorly understood. This review gives a brief overview of the contribution of the neuronal GA in the pathogeneses of neurodegeneration, summarizes what is known of the GA machinery in these diseases, and present the relationship between GA fragmentation and the aggregation and accumulation of misfolded or aberrant proteins including mutant SOD1, a-synuclein, tau, which is considered to be a key event in the pathogenic process, and perturbating in calcium homeostasis, regulation of hormones, lipid metabolism are also linkage to the function of the GA thought to underlie neurodegeneration. Although these precise diseases mechanisms remain to be clarified, more research is needed to better understand how GA function for it and to enable physicians to use this knowledge for the benefit of the patients.     

供应室多功能器械分类台的研制与实验研究

目的 为控制医院内感染,避免回收的医疗器械对供应室洗涤问的二次污染.方法 自行设计多功能器械分类台,将回收器械的清点、分类、摆放于一体;台面不必垫衬吸水棉布而让污水集中自动直接流入排水口而进入下水道;工作结束后组件可拆洗消毒.结果 避免了清点、分类、摆放器械时相互碰撞,有效缩短了清点时间,也减少了污染机会;避免了垫衬吸水棉布造成人力、物力和时间的浪费及对环境的再污染;消毒后2种台面消毒效果比较,差异有统计学意义(P＜0.01).结论 多功能器械台的研制,使回收处理污染器械工作更加规范,去污染更加彻底.     

普林格尔治疗仪结合手法按摩治疗乳汁淤积的疗效观察

目的：观察普林格尔治疗仪结合手法按摩乳房对产妇乳汁淤积的治疗效果。方法将128例乳汁淤积的产妇随机分为两组，观察组64例采用普林格尔产后治疗仪结合手法按摩并人工挤奶；对照组64例按传统方法，手法按摩后行人工挤奶。观察并比较两组产妇乳腺管通畅情况，乳汁排出情况。结果观察组疗效优于对照组，差异有统计学意义。结论普林格尔产后治疗仪结合手法按摩乳房治疗产后乳汁淤积效果优于传统的局部按摩挤奶。     

小儿呼吸道感染所伴痰症的辨治

小儿呼吸道感染所伴痰证,按疾病的发生、发展、变化的过程,归纳为三期六型分治,简明扼要,易于辨证治疗,对临床西医工作者亦容易理解和应用,痰证各期之间有一定联系,各期各型之间又可单独论治。     

邱志楠教授治痰经验探微

痰是呼吸疾病的重要病理基础,又是其临床重要特点,也是临床表现之一.临床常常清肺、健脾燥湿、补肾并举,寒温并用,攻补兼施,治愈许多疑难疾病,治痰也堪称一绝.     

Canalicular stenosis secondary to weekly docetaxel: a potentially preventable side effect.

BACKGROUND: The purpose of this study was to describe canalicular stenosis as a mechanism for epiphora (excessive tearing) secondary to weekly docetaxel. PATIENTS AND METHODS: Fourteen patients with metastatic breast cancer who developed epiphora during weekly docetaxel therapy underwent an ophthalmologic examination, and probing and irrigation of the nasolacrimal ducts. The total duration of docetaxel therapy, the duration of treatment at the time of onset of epiphora, the number of infusions, the cumulative dose of docetaxel and the severity of canalicular stenosis were recorded. RESULTS: All 14 patients had anatomic narrowing of the canaliculi as the underlying mechanism for epiphora. Bicanalicular silicone intubation or dacryocystorhinostomy (DCR) was recommended for all 14 patients. Eleven patients underwent surgery and experienced resolution of their symptoms. The three patients who declined surgery continue to have epiphora at the time of this report. CONCLUSIONS: Canalicular stenosis is an underlying mechanism for epiphora in patients receiving weekly docetaxel. Bicanalicular silicone intubation should be considered early in the course of weekly docetaxel therapy to prevent complete closure of the canaliculi. Once complete or near complete stenosis of the canaliculi occurs, DCR with a permanent pyrex glass tube placement may become necessary to overcome the blockage of tear outflow.