推按运经仪治疗胆石病536例临床观察

胆石病是世界范围的胆道系统主要疾病，国内普查自然人群中，胆结石患病率为１－１０％，而且有逐年增高的趋势。以往应用传统手术疗法虽有一定疗效，但也存在不少问题。运用推按运经仪治疗胆石病５３６例，总有效率为９１．９７％。     

Automatic jet ventilation in children anaesthetized by the T-piece circuit

Investigation was carried out in ten children aged between one month and six years, who were anaesthetized by the T-piece circuit. The volume of the reservoir tubing of the T-piece was 250 ml. Ventilation was controlled automatically by oxygen jets which were delivered via an injector attached to the reservoir tubing. The oxygen jets were regulated by an electronically-controlled solenoid valve. The children were ventilated by a tidal volume about 12 ml±kg^?1 at a rate of 12-20 per min depending on their age, while the FGF varied between 3 and 6 l min^?1 depending on their body weight. The resulting FIO₂ ranged between 0.32 and 0.34 which was expected from the oxygen:nitrous oxide mixture (1:2), denoting no mixing of the oxygen jets with the anaesthetic mixture. The PA_co2 was ventilation-dependent, and ranged between 4±6-5±3 kPa (35-41 mmHg). The results suggest that automatic jet ventilation facilitates controlled ventilation in children anaesthetized by the T-piece circuit, while maintaining the original simplicity of the T-piece.;     

机械通气病人吸痰吸引负压研究现状

介绍了国内外机械通气病人吸痰时吸引负压的选择。提示护士在机械通气病人护理过程中应根据病人的具体情况合理选择。     

音乐疗法在婴儿吸痰中的应用研究

目的　采用音乐疗法减轻患儿吸痰时的烦躁、哭闹，减轻氧的消耗，缓解缺氧情况。方法 采用实验性研究设计，选择北京儿童医院ICU病房住院的52名需吸痰患儿为研究对象，选择背景音乐为节奏舒缓的钢琴曲。记录有与无背景音乐时吸痰前后患儿的经皮氧饱和度和心率的变化。结果 对同一患儿进行了干预前后的分析比较，有与无背景音乐下吸痰患儿经皮氧饱和度、心率有显著性差异。结论 音乐疗法对于缓解ICU吸痰患儿缺氧是一种有效干预手段。     

化痰通络法治疗脊髓炎后遗症

介绍魏品康教授治疗脊髓炎后遗症一则,以化痰通络法贯穿始终。     

肺部疾病中痰巨噬细胞对结核菌素试验反应的临床研究

目的:测定肺结核、肺肿瘤及非特异性炎症患者注射结核菌素前后痰巨噬细胞的不同数量变化,由此提供一种新的鉴别诊断方法。方法:皮内注射结核菌素、收集注射前、后痰液,测定痰巨噬细胞在不同时间的数量变化。结果:肺结核病人在结核菌素试验后痰巨噬细胞明显增加,肺部肿瘤及非特异性炎症则无显著性变化。结论:肺部患者测定结核菌素前后痰巨噬细胞变化,可作为菌阴肺结核与肺部肿瘤及非特异性炎症鉴别诊断依据之一。     

皮肤发疱仪的研制与临床应用

目的：研制皮肤发疱仪，并临床应用于自体表皮移植治疗白癜风，分析治疗效果。方法：根据局部皮肤双控发疱理论，应用负反馈原理，研制出皮肤双控发疱仪；该仪器应用于自体表皮移植治疗白癜风，通过控制局部发疱部位的压力和温度，实现发疱时需要的恒压和恒温。结果：皮肤发疱仪能恒定控制局部皮肤发疱时的压力和温度，使自体表皮移植治疗白癜风的总成活率达到98．01％。结论：皮肤发疱仪性能稳定，操作方便，临床应用效果好，值得推广。     

应用微波技术切割睑球粘连22例

目的探讨微波热凝切割睑球粘连的治疗效果。方法随机抽取１９９５年１月～１９９７年１２月我科应用微波治疗睑球粘连２２例进行回顾性总结。结果２２例轻、中、重度睑球粘连患者，经１～４次热凝切割，均痊愈。结论微波技术切割睑球粘连操作简便易行，是一种较为理想的治疗方法。     

Sputum induction as a research tool for the study of human respiratory mucus

The study objectives were to compare in vitro transportability and physical properties of respiratory mucus, obtained invasively by direct collection (DC) right after endotracheal intubation and non-invasively by sputum induction with 3% hypertonic saline solution inhalation (SI) 24 h before the anesthesia. Twenty-two patients with no pulmonary disease scheduled for elective abdominal surgical procedures were studied. The parameters analyzed and the main results are as follows. (1) Transportability by cilia (MCT), SI was higher than DC (0.94+/-0.25 and 0.62+/-0.25; P<0.001). There was a significant correlation between the two methods and DC could be estimated by: DC=0.21+(0.44 SI) (r=0.44; P<0.001). (2) Transportability by cough (CC), SI was higher than DC (68.23+/-32.1 and 33.58+/-19.04 mm; P=0.002). (3) Contact angle (CA), SI was lower than DC (10+/-3 degrees and 22+/-14 degrees ; P=0.025). (4) Rheological properties (no significant difference obtained between SI and DC). These results indicated that SI changes mucus physical properties and transportability in non-expectorators.     

Are transforming properties of the bovine papillomavirus E5 protein shared by E5 from high-risk human papillomavirus type 16?

The E5 proteins of bovine papillomavirus type 1 (BPV-1) and human papillomavirus type 16 (HPV-16) are small (44-83 amino acids), hydrophobic polypeptides that localize to membranes of the Golgi apparatus and endoplasmic reticulum, respectively. While the oncogenic properties of BPV-1 E5 have been characterized in detail, less is known about HPV-16 E5 due to its low expression in mammalian cells. Using codon-optimized HPV-16 E5 DNA, we have generated stable fibroblast cell lines that express equivalent levels of epitope-tagged BPV-1 and HPV-16 E5 proteins. In contrast to BPV-1 E5, HPV-16 E5 does not activate growth factor receptors, phosphoinositide 3-kinase or c-Src, and fails to induce focus formation, although it does promote anchorage-independent growth in soft agar. These variant activities are apparently unrelated to differences in intracellular localization of the E5 proteins since retargeting HPV-16 E5 to the Golgi apparatus does not induce focus formation.