全文获取类型
收费全文 | 43260篇 |
免费 | 4723篇 |
国内免费 | 1248篇 |
专业分类
耳鼻咽喉 | 179篇 |
儿科学 | 612篇 |
妇产科学 | 1812篇 |
基础医学 | 2872篇 |
口腔科学 | 619篇 |
临床医学 | 10756篇 |
内科学 | 5417篇 |
皮肤病学 | 441篇 |
神经病学 | 1298篇 |
特种医学 | 2385篇 |
外国民族医学 | 10篇 |
外科学 | 3796篇 |
综合类 | 7450篇 |
现状与发展 | 3篇 |
一般理论 | 5篇 |
预防医学 | 3796篇 |
眼科学 | 614篇 |
药学 | 3284篇 |
105篇 | |
中国医学 | 2085篇 |
肿瘤学 | 1692篇 |
出版年
2024年 | 248篇 |
2023年 | 998篇 |
2022年 | 1875篇 |
2021年 | 2241篇 |
2020年 | 2544篇 |
2019年 | 2067篇 |
2018年 | 2020篇 |
2017年 | 2100篇 |
2016年 | 2076篇 |
2015年 | 2062篇 |
2014年 | 3612篇 |
2013年 | 3714篇 |
2012年 | 2813篇 |
2011年 | 2948篇 |
2010年 | 2220篇 |
2009年 | 1993篇 |
2008年 | 2017篇 |
2007年 | 1951篇 |
2006年 | 1659篇 |
2005年 | 1315篇 |
2004年 | 1077篇 |
2003年 | 945篇 |
2002年 | 700篇 |
2001年 | 588篇 |
2000年 | 455篇 |
1999年 | 416篇 |
1998年 | 327篇 |
1997年 | 330篇 |
1996年 | 296篇 |
1995年 | 240篇 |
1994年 | 206篇 |
1993年 | 168篇 |
1992年 | 144篇 |
1991年 | 124篇 |
1990年 | 106篇 |
1989年 | 78篇 |
1988年 | 78篇 |
1987年 | 63篇 |
1986年 | 68篇 |
1985年 | 92篇 |
1984年 | 68篇 |
1983年 | 25篇 |
1982年 | 51篇 |
1981年 | 32篇 |
1980年 | 27篇 |
1979年 | 22篇 |
1978年 | 12篇 |
1977年 | 6篇 |
1976年 | 6篇 |
1973年 | 4篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
41.
目的探讨高频超声引导定位穿刺前臂浅静脉的应用价值。方法对40例常规浅静脉穿刺失败,采用高频探头在同一体表区域寻找并标记浅静脉走行及深度,确认进针方向后再次静脉穿刺,必要时采用实时引导。结果11例经高频超声标记、29例经高频超声实时引导静脉穿刺均一次成功。结论高频超声引导下静脉穿刺的成功率高,无并发症,是一种简便有效的方法,值得在临床推广应用。 相似文献
42.
Chang Hyun Lee Jung-Gi Im Jin Mo Goo Hyun Ju Lee Sung-Tae Hong Cheng Hua Shen Doo Hyun Chung Kyu Ri Son Jung Min Chang Hong Eo 《Korean journal of radiology》2007,8(5):372-381
OBJECTIVE: To investigate the serial CT findings of Paragonimus westermani infected dogs and the microscopic structures of the worm cysts using Micro-CT. MATERIALS AND METHODS: This study was approved by the committee on animal research at our institution. Fifteen dogs infected with P. westermani underwent serial contrast-enhanced CT scans at pre-infection, after 10 days of infection, and monthly thereafter until six months for determining the radiologic-pathologic correlation. Three dogs (one dog each time) were sacrificed at 1, 3 and 6 months, respectively. After fixation of the lungs, both multi-detector CT and Micro-CT were performed for examining the worm cysts. RESULTS: The initial findings were pleural effusion and/or subpleural ground-glass opacities or linear opacities at day 10. At day 30, subpleural and peribronchial nodules appeared with hydropneumothorax and abdominal or chest wall air bubbles. Cavitary change and bronchial dilatation began to be seen on CT scan at day 30 and this was mostly seen together with mediastinal lymphadenopathy at day 60. Thereafter, subpleural ground-glass opacities and nodules with or without cavitary changes were persistently observed until day 180. After cavitary change of the nodules, the migratory features of the subpleural or peribronchial nodules were seen on all the serial CT scans. Micro-CT showed that the cyst wall contained dilated interconnected tubular structures, which had communications with the cavity and the adjacent distal bronchus. CONCLUSION: The CT findings of paragonimiasis depend on the migratory stage of the worms. The worm cyst can have numerous interconnected tubular channels within its own wall and these channels have connections with the cavity and the adjacent distal bronchus. 相似文献
43.
44.
彩超引导介入治疗腘窝囊肿23例 总被引:3,自引:0,他引:3
目的探讨彩超引导下腘窝囊肿介入治疗的价值。方法在彩超引导下穿刺囊肿并抽尽囊液,生理盐水反复冲洗囊腔后注入无水乙醇,5min后抽出,反复2~3次。结果23例中22例穿刺一次治愈,1例穿刺2次治愈。23例随访6个月,无复发。结论彩超引导下介入治疗腘窝囊肿操作简便,创伤轻微,安全可靠,效果显著,可重复操作。 相似文献
45.
BACKGROUND AND PURPOSE: The Doppler waveform patterns of loss of diastolic flow, appearance of retrograde diastolic flow, or no detectable flow in the cerebral arteries suggest significantly abnormal cerebral blood flow (CBF). A retrospective study was performed to show that significantly abnormal CBF alone, without clinical criteria, is not necessarily specific to brain death in the young pediatric population. PATIENTS AND METHODS: Forty-seven pediatric patients, from newborn to 4 years of age, were found to have significantly abnormal CBF, including 7 patients with loss of diastolic flow, 28 with retrograde diastolic flow, and 23 with no detectable cerebral flow on serial Doppler sonographic examinations. Their clinical data and sonographic results were collected and analyzed. RESULTS: Forty-two patients died, a few of whom had only transient improvement of cerebral flow. All of the patients with no detectable cerebral flow expired. Five patients survived with or without sequelae. Their underlying conditions that caused increased intracranial pressure were treated by medical and/or surgical intervention, and diastolic reversal of CBF corrected within 1 day in all 5. CONCLUSIONS: Although no detectable flow is a lethal sign, pediatric patients with loss or reversal of diastolic flow may survive with prompt and effective treatment. Using Doppler ultrasound to diagnose cerebral circulatory arrest should be done with caution in pediatric patients. 相似文献
46.
B. Jahn-Schmid C. Harwanegg† R. Hiller† B. Bohle C. Ebner O. Scheiner M. W. Mueller† 《Clinical and experimental allergy》2003,33(10):1443-1449
BACKGROUND: The availability of recombinant allergens and recent advances in biochip technology led to the development of a novel test system for the detection of allergen-specific IgE. OBJECTIVE: To test the performance of this allergen microarray in a serological analytical study. METHODS: Standard allergens contained in grass pollen (Phl p 1, Phl p 2, Phl p 5 and Phl p 6) and tree pollen (Bet v 1 and Bet v 2) were used as a model system. The detection of allergen-specific serum IgE using microarrays was compared with standard test systems: CAP/RAST and an in-house ELISA. In order to test the analytical sensitivity of the assays, geometric dilutions of a serum pool containing high levels of pollen-specific IgE from allergic individuals were tested in each system. To assess the analytical specificity, the sera of 51 patients with presumptive allergic symptoms were collected before diagnosis. Thereafter, the results for grass/tree-pollen-specific IgE were compared. RESULTS: The microarray has a good dynamic range similar to the CAP/RAST system. Microarray and ELISA showed comparable analytical sensitivity exceeding the CAP/RAST system. With respect to the analytical specificity, no significant cross-reactivity of the allergens was observed. For two of the allergens tested, weak positive signals were detected in the microarray test system, whereas they were not detectable by CAP/RAST. CONCLUSION: A good correlation of presently used methods to detect serum IgE and the novel microarray test system was observed. As a next step, a careful validation of this method for a multitude of allergens and a thorough clinical evaluation has to be provided. Microarray testing of allergen-specific IgE can be presumed to be the method of choice for a prospective component-resolved diagnosis of Type I allergy, and the basis for the design and monitoring of a patient-tailored specific immunotherapy in the future. 相似文献
47.
48.
J. B. DILAWARI N. NAGPAL Y. K. CHAWLA U. KAUR J. VERMA H. BALI K. M. DAS S. SURI 《Journal of gastroenterology and hepatology》1993,8(2):202-205
Hepatic venous outflow tract obstruction, Budd-Chiari syndrome (BCS), leads to portal hypertension and to the development of collaterals that bypass the obstruction. Described here is a BCS patient with an unusually large transdiaphragmatic collateral between the left hepatic and left innominate veins, which decompressed the oesophageal varices. This has not been reported earlier in the literature. 相似文献
49.
Philippe Brun Heykel Kchouk Brigitte Mouchet Véronique Baudouin Alain Raynaud Chantal Loirat Annabelle Azancot-Benisty 《Pediatric nephrology (Berlin, Germany)》1997,11(1):27-30
To evaluate the reliability of Doppler ultrasonography (US) in identifying children with renal artery stenosis (RAS) among
those with hypertension, we compared Doppler US results in 22 hypertensive children (mean age 8.9±4.3 years), with (13 cases)
and without RAS at angiography, and in 33 normotensive children (mean age 8.8±4.7 years). We observed 2 false-negatives and
2 false-positives with Doppler US. Of the 2 false-negative diagnoses, 1 had RAS on an accessory renal artery located behind
a normal upper polar artery and the other was observed in a patient with bilateral multiple stenosis of the very distal segments
of renal arteries. The 2 false-positive diagnoses were due to sinuous left renal artery and to technical reasons, respectively.
In another patient, Doppler US showed a tight RAS, while arteriography was normal. RAS was subsequently confirmed by a second
arteriography. Peak systolic velocity values of Doppler US were significantly higher in patients with proven angiographic
RAS (3.44±0.66 m/s) than in hypertensive patients with normal renal arteries at angiography (0.99±0.35 m/s, P <0.0001) and normotensive healthy children (1.04±0.23 m/s, P <0.0001). With the use of multiple views, and the experience acquired with practice, false-negatives or false-positives due
to the geometry of the renal artery can be avoided. Nevertheless, very distal stenosis can be missed by Doppler US.
Received October 30, 1995; received in revised form April 16, 1996; accepted May 14, 1996 相似文献
50.
Priv.-Doz. Dr. V. Nutz M. Peschen 《Langenbeck's archives of surgery / Deutsche Gesellschaft fur Chirurgie》1992,377(6):372-377
Summary A duplex ultrasound system was used to examine the blood flow of the common femoral artery in ten young patients with fractures of the lower extremities. Two patients had fractures of both legs. In eight patients the blood flow in the injuried leg was comparable with that in the not injured leg. The flow alterations were measured on 3–7 different days over a period of 6–224 days after trauma. All patients showed a significant (to twice or three times that before injury) increase in blood flow in the injured leg a few days after trauma and/or operation, whereas the blood flow in the uninjured leg remained the same or even decreased a little. In the case of undisturbed fracture healing the change in blood flow disappeared within 8–12 weeks, corresponding to fracture consolidation. When fracture healing was delayed and/or further operations on the injured leg were necessary, the blood flow was increased for much longer. The hemodynamics of an injured extremity are compared with those reported elsewhere in the literature. The increased demand for oxygen or energy can explain the changes only in part. Another function of the reflective increase in blood flow could be the temperature increase in the extremity.
Doppler-sonographische durchblutungsmessungen der unteren extremität des menschenII. Hämodynamik nach trauma und operation
Zusammenfassung Mittels Doppler-sonographischer Durchblutungsmessung wurde die Hämodynamik der verletzten Extremität an 10 jungen Patienten mit Frakturen der unteren Extremität untersucht. Bei 8 Patienten konnte die Durchblutung des verletzten Beins mit der unverletzten Gegenseite verglichen werden. Die Messungen erfolgten an 3–7 verschiedenen Tagen in einem Zeitraum von 6–224 Tagen nach dem Unfall. An allen verletzten Extremitäten steigt die Durchblutung wenige Tage nach dem Unfall und/oder der Operation deutlich um das 2- bis 3fache an, während die Durchblutung des unverletzten Beins niedrig bleibt. Bei einem ungestörten klinischen Verlauf sinkt die Durchblutung in 8–12 Wochen wieder. Heilungsstörungen und weitere Operationen an dem Bein verzögern diese Normalisierung deutlich. Diese Ergebnisse werden mit anderen Untersuchungen der Literatur verglichen. Ursache und Funktion der hämodynamischen Änderungen könnte u. a. in einer reflektorischen Temperaturerhöhung zu sehen sein.相似文献