个性化护理提高食管癌术后患者使用漱口液漱口的依从性

目的探讨个性化护理提高食管癌术后患者使用漱口液漱口依从性的效果。方法便利抽样法选择2012年3月至2014年2月,解放军海军总医院胸外科收治的行开胸术的食管癌患者122例为研究对象,按入院先后将其分为观察组62例和对照组60例,对照组常规使用漱口液护理,观察组在对照组的基础上予以个性化护理,比较两组患者使用漱口液的依从性及口腔溃疡的分级与发生率。结果观察组患者使用漱口液的依从性优于对照组(U=1318,P0.05),口腔溃疡的分级及发生率均优于或低于对照组,差异均有统计学意义(均P0.05)。结论对食管癌术后患者进行个性化护理,可提高患者使用漱口液的依从性,降低口腔溃疡的发生率。     

Triphala,a New Herbal Mouthwash for the Treatment of Gingivitis: A Randomized Controlled Clinical Trial

Background: An antiplaque agent with minimal side effects that can be used as an effective adjunct to mechanical plaque control is needed. The current study is designed to evaluate efficacy of triphala (TRP) mouthwash in reduction of plaque and gingivitis. Methods: Ninety individuals with chronic generalized gingivitis were randomly assigned to three groups: 1) group I, placebo mouthwash; 2) group II, TRP mouthwash; and 3) group III, chlorhexidine (CHX) mouthwash. All individuals were instructed to rinse with their respective mouthwash twice daily. 1) Plaque index (PI); 2) gingival index (GI); 3) oral hygiene index‐simplified (OHI‐S); and 4) microbiologic colony counts were recorded at baseline and at 7, 30, and 60 days. Results: All three groups showed gradual reduction in PI, GI, and OHI‐S levels from baseline to 7, 30, and 60 days. There was also significant reduction in microbial counts in all groups at all time intervals except in group I. A significant difference was noticed with respect to reduction in PI, GI, OHI‐S, and microbiologic counts in group I compared with groups II and III. However, no significant differences were found between groups II and III for any parameters at any time intervals. Conclusions: TRP mouthwash was found to decrease inflammatory parameters from baseline to follow‐up intervals. Because improvement in gingivitis was comparable with that of CHX mouthwash, TRP mouthwash can be considered a potential therapeutic agent in the treatment of gingivitis.     

中药“口康”含漱液对口腔致病微生物体外抑菌试验

目的：检测中药“口康”含漱液的抑菌作用及强度,为临床治疗口腔感染疾病提供实验依据。方法：将琼脂培养基与不同梯度的“口康”含漱液混合,灭菌后倒皿,再接种口腔感染致病菌,同时,作一无药培养基对照,培养1d后观察结果,以最低药物浓度不长菌者为该菌株MIC值。结果：49株口腔致病菌中,27株革兰氏阴性杆菌MIC范围0.03-1.0g/ml,MIC50均为0.125g/ml,MIC90为0.125-0.5g/ml;21株革兰氏阳性球菌MIC范围0.008-0.5g/ml,MIC500.015-0.125g/ml,MIC50为0.015-0.5g/ml;1株白色念珠菌MIC0.015g/ml。结论：“口康”含漱对各类不同口腔致病株均有抑菌作用;对革兰阳性球菌抑菌强度更佳,为革兰阴性杆菌的2－8个对比倍数;对念珠性霉菌抑菌作用较强。     

An in vivo study of the plaque control efficacy of Persica: a commercially available herbal mouthwash containing extracts of Salvadora persica

AIM: This study compared the oral health efficacy of Persica mouthwash (containing an extract of Salvadora persica) with that of a placebo. DESIGN: In a double-blind, cross-over trial, participants were randomly allocated to use either the Persica mouthwash or a placebo for a three-week period. Plaque accumulation, gingival bleeding and the salivary concentrations of mutans streptococci (MS) were measured before and immediately following the experimental period. After an eight-week 'washout' period, the study was repeated with participants using the alternative mouthwash. PARTICIPANTS: Twenty-eight healthy students (aged between 18 and 42 years) volunteered to take part in this investigation. RESULTS: Compared with the pre-treatment values, both placebo and experimental groups demonstrated significantly reduced gingival bleeding (p < 0.01). Plaque scores were not significantly reduced following use of either Persica or the placebo. However, the use of Persica, but not the placebo, resulted in significant reduction in the carriage of MS (p < 0.05). CONCLUSION: Use of Persica mouthwash resulted in improved gingival health and lower carriage rate of cariogenic bacteria when compared with the pre-treatment values. The placebo (vehicle control) also improved gingival health significantly. Neither the Persica nor the placebo reduced the accumulation of dental plaque.