全文获取类型
收费全文 | 51959篇 |
免费 | 5789篇 |
国内免费 | 1424篇 |
专业分类
耳鼻咽喉 | 599篇 |
儿科学 | 851篇 |
妇产科学 | 887篇 |
基础医学 | 2211篇 |
口腔科学 | 1320篇 |
临床医学 | 10288篇 |
内科学 | 5067篇 |
皮肤病学 | 687篇 |
神经病学 | 2254篇 |
特种医学 | 1244篇 |
外国民族医学 | 5篇 |
外科学 | 4199篇 |
综合类 | 6960篇 |
现状与发展 | 1篇 |
一般理论 | 3篇 |
预防医学 | 9723篇 |
眼科学 | 758篇 |
药学 | 4643篇 |
217篇 | |
中国医学 | 4437篇 |
肿瘤学 | 2818篇 |
出版年
2024年 | 250篇 |
2023年 | 1332篇 |
2022年 | 1808篇 |
2021年 | 2840篇 |
2020年 | 3040篇 |
2019年 | 2519篇 |
2018年 | 2294篇 |
2017年 | 2589篇 |
2016年 | 2490篇 |
2015年 | 2392篇 |
2014年 | 4208篇 |
2013年 | 4401篇 |
2012年 | 3629篇 |
2011年 | 3544篇 |
2010年 | 2727篇 |
2009年 | 2631篇 |
2008年 | 2631篇 |
2007年 | 2463篇 |
2006年 | 2238篇 |
2005年 | 1770篇 |
2004年 | 1452篇 |
2003年 | 1200篇 |
2002年 | 941篇 |
2001年 | 764篇 |
2000年 | 568篇 |
1999年 | 449篇 |
1998年 | 339篇 |
1997年 | 319篇 |
1996年 | 254篇 |
1995年 | 239篇 |
1994年 | 172篇 |
1993年 | 156篇 |
1992年 | 138篇 |
1991年 | 72篇 |
1990年 | 58篇 |
1989年 | 53篇 |
1988年 | 34篇 |
1987年 | 34篇 |
1986年 | 15篇 |
1985年 | 24篇 |
1984年 | 28篇 |
1983年 | 12篇 |
1982年 | 14篇 |
1981年 | 15篇 |
1980年 | 7篇 |
1979年 | 8篇 |
1978年 | 3篇 |
1973年 | 2篇 |
1972年 | 1篇 |
1966年 | 1篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
141.
Masahiko Harano Masatoshi Eto Motonobu Nakamura Yoshihiro Hasegawa Motonori Kano Akito Yamaguchi Seiji Naito 《International journal of urology》2007,14(2):112-117
OBJECTIVE: To assess the functional results, health-related quality of life (QOL) outcomes, and complications in patients with an ileal neobladder in comparison to those with cutaneous diversion (ileal conduit and cutaneostomy). METHODS: Between September 1992 and February 2003, we consecutively performed an ileal neobladder (the Studer method) in 30 patients and cutaneous diversion in 38 patients. In August 2004, questionnaires were mailed to 54 patients. The questionnaire included the validated health-related quality of life (QOL) questionnaire, SF-36 General Health Survey, and a urinary incontinence questionnaire. We also evaluated the functional results in patients with an ileal neobladder and the postoperative complications in patients with both urinary diversions. RESULTS: The data from 41 patients (21 ileal neobladder procedures and 20 cutaneous diversions) were available for the analysis. No differences in the overall QOL were observed between the two groups. Complete daytime and night-time urinary continence was achieved in the 21 patients (100%) and 13 patients (61.9%), respectively. The mean value of the maximum flow rate was 15 +/- 12 mL/min in the 21 neobladder patients. There were 19 early complications in 18 patients (60.0%) and seven late complications in six patients (20.0%) with an ileal neobladder. However, there were 15 early complications in 14 patients (36.8%) and eight late complications in six patients (15.8%) with cutaneous diversions. CONCLUSION: The findings regarding the health-related QOL and the frequency of complications in the neobladder group and those in the cutaneous diversion group were similar. However, the functional results and the status of urinary continence in the neobladder patients were satisfactory. 相似文献
142.
Seiichi Saito Shunichi Namiki Kenji Numahata Makoto Satoh Shigeto Ishidoya Akihiro Ito Haruo Nakagawa Yasuhiro Kaiho Takehiko Sanada Atsushi Yamada Yoichi Arai 《International journal of urology》2007,14(2):133-139
PURPOSE: To determine the effect of an interposition nerve graft on sexual function after radical prostatectomy. METHODS: This study includes 64 patients, without hormonal therapy, who underwent a radical prostatectomy and intraoperative electrophysiological confirmation of cavernous nerve preservation. Twelve patients underwent a unilateral interposition sural nerve graft (UNG) for the resected neurovascular bundle. Twenty-one and 31 patients underwent bilateral nerve-sparing (BNS) and unilateral nerve-sparing (UNS) surgery without a nerve graft, respectively. As the age of patients was significantly younger in the UNG group than in the other groups, age-matched analysis also was conducted. Sexual function, evaluated by a self-administered questionnaire using the University of California Los Angeles-Prostate Cancer Index, was compared statistically among the three groups. RESULTS: In the age-matched analysis, the postoperative sexual function (SXF) score of the UNG group showed an intermediate level of recovery between those of the BNS and UNS groups at 12 months and reached the same level as the score at 12 months of the BNS group at 18 months postoperatively. The difference in the SXF score between the UNG and UNS groups began to appear after 6 months postoperatively and increased steadily with time. However, the background factors, such as the baseline SXF score, the usage rate of phosphodiesterase 5 inhibitors, and the rate of comorbidities were different between the UNG and UNS groups. CONCLUSIONS: The difference of the SXF score between the UNG and UNS groups increased with time after 6 months postoperatively. However, it might be difficult at present to attribute a better recovery of the SXF score to the nerve graft because of the difference in the background factors between the groups. 相似文献
143.
To evaluate the long-term effects of entacapone on both mean daily 'on' time and health-related quality of life (QoL) in patients with Parkinson's disease (PD) experiencing 'end-of-dose' motor fluctuations and the benefits of an early therapeutic intervention. A prospective, multicenter, observational, 12-month study was performed with an initial 3-month intervention phase, consisting of a phone call to half of the patients from randomly selected investigators to assess if dose adjustment was necessary. Effectiveness was determined by home diaries ('on' time), subscales II and III of the Unified Parkinson's Disease Rating Scale (UPDRS), and the Parkinson's Disease Questionnaire (PDQ-8). After 3 months of treatment, 4.0% of the intervention group patients discontinued the study, versus 18.4% in the control group ( P < 0.01). The improvement in 'on' time was significantly increased since the 3-month visit (21%, P < 0.0001) until the end of the study (23% at 12 months, P < 0.0001). Entacapone also induced significant reductions in the UPDRS scores for subscales II and III and in the PDQ-8 score. 11.2% of patients experienced at least one adverse reaction. This study confirms the effectiveness of entacapone in reducing motor fluctuations by increasing 'on' time, and in improving QoL of PD patients. An early adjustment of entacapone and levodopa doses reduces the number of treatment discontinuations during the first months of treatment. 相似文献
144.
Boris A. Zelle MD Andrea S. Herzka MD Christopher D. Harner MD James J. Irrgang PhD PT ATC 《Operative Techniques in Orthopaedics》2005,15(1):76
Clinical outcomes data can be used to facilitate patient management decisions, assess clinician and organizational performance, and to provide evidence for the effectiveness of surgery and rehabilitation. The validity of the inferences made from outcomes data are dependent on the validity of the outcomes measures themselves and the circumstances under which the data were collected, analyzed, and interpreted. Clinical outcomes may include measures of impairment of body structure and function, activity limitation, and participation restriction. However, because the relationship between impairment and the resulting activity limitation and participation restriction is not direct, and because activity limitations and participation restrictions are of the utmost concern to the athlete, the primary clinical outcome should be measures of activity limitation and participation restriction. Activity limitation and participation restriction may be measured either through direct observation of performance or by general or specific measures of health related quality of life. Clinical outcomes data must be collected systematically to ensure valid inferences from the data. 相似文献
145.
V Ahern E‐S Koh V Gebski Y Sathiyaseelan 《Journal of Medical Imaging and Radiation Oncology》2007,51(5):458-464
The purpose of this study was to document how children in Australia with medulloblastoma are being treated and to evaluate the quality of radiotherapy (RT) delivered. The Radiotherapy Database of the Australian and New Zealand Children’s Haematology and Oncology Group was used to identify 46 children with medulloblastoma younger than the age of 15 years treated with radical intent by craniospinal irradiation between 1997 and 1999 inclusively. Twenty‐six patients had completely resected disease without evidence of disease spread. Of these, 16 patients received a craniospinal RT dose of <25 Gy in addition to chemotherapy. RT treatment immobilization methods varied, as did planning methods. RT dose to critical structures was recorded on treatment plans for only 15% of patients. The average systematic error in shield placement at the posterior orbit was 5.2 mm, and two‐thirds of patients were ‘overshielded’ at this site. Adequate coverage of the distal end of the thecal sac was achieved in fewer than 50% of on‐treatment verification films for 21 of 45 patients. With a reduction in RT dose to the craniospinal axis for paediatric medulloblastoma, greater attention is needed for patient immobilization, documentation of RT dose to critical structures and the placement and reproducibility of shielding. 相似文献
146.
Jessica Swoboda DDS H. Asuman Kiyak MA PhD Rigmor E. Persson DDS MSD G. Rutger Persson DDS PhD David K. Yamaguchi PhD Michael I. MacEntee LDS FRCD© PhD Christopher C.L. Wyatt BSc DMD MSc 《Special care in dentistry》2006,26(4):137-144
There is limited information regarding oral health status and other predictors of oral health‐related quality of life. An association between oral health status and perceived oral health‐related quality of life (OHQOL) might help clinicians motivate patients to prevent oral diseases and improve the outcome of some dental public health programs. This study evaluated the relationship between older persons' OHQOL and their functional dentition, caries, periodontal status, chronic diseases, and some demographic characteristics. A group of 733 low‐income elders (mean age 72.7 ISD=4.71, 55.6% women, 55.1% members of ethnic minority groups in the U.S. and Canada) enrolled in the TEETH clinical trial were interviewed and examined as part of their fifth annual visit for the trial. OHQOL was measured by the Geriatric Oral Health Assessment Index (GOHAI); oral health and occlusal status by clinical exams and the Eichner Index; and demographics via interviews. Elders who completed the four‐year assessment had an average of 21.5 teeth (SD=6.9). with 8.5 occluding pairs (SD=4.6), and 32% with occlusal contacts in all four occluding zones. Stepwise multiple regressions were conducted to predict total GOHAI and its subscores (Physical, Social, and Worry). Functional dentition was a less significant predictor than ethnicity and being foreign‐bom. These variables, together with gender, years since immigrating, number of carious roots, and periodontal status, could predict 32% of the variance in total GOHAI, 24% in Physical, 27% in Social, and 21 % in the Worry subscales. These findings suggest that functional dentition and caries influence older adults' OHQOL, but that ethnicity and immigrant status play a larger role. 相似文献
147.
中老年晚期非小细胞肺癌射频损毁治疗与化疗的临床比较 总被引:1,自引:1,他引:0
目的:探讨射频损毁治疗晚期非小细胞肺癌的疗效及应用价值。方法:自1999年12月至2000年8月收治73例晚期中老年非小细胞肺癌患者,分别给予射频损毁治疗和以铂类为主的联合化疗;观察比较其近期疗效、中位生存期、1年及2年生存率;并分析其治疗后生存质量。结果:射频损毁治疗组有效率(CR+PR)为71.5%(30/42),明显高于化疗组的43.3%,差异呈显著性,(x2=4.63,P<0.05)。射频损毁治疗组中位生存期、1年及2年生存率及治疗后生存质量均高于化疗组。结论:射频损毁治疗对晚期非小细胞肺癌治疗,具有较好的中期疗效,且能明显提高生存质量。 相似文献
148.
149.
150.
L. Kebbon 《Journal of intellectual disability research : JIDR》1997,41(2):120-125
The most spectacular contribution from the nordic countries to intellectual disability policy is probably the idea of normalization, but it is not the simplistic notion that can be inferred from international debate. Its major significance may have been to act as an inspiring catchword for the important trend away from institutions Into integrated living. However, it is more fully understood when seen in the concrete context where It has successively developed, and been critically analysed and tested in operation. Scandinavian sociologists and psychologists—as well as politicians—were also among the first to use the concept of quality of life for analysis of social policy, including intellectual disability. The primary medium for implementation has been legislation, where the dominant difficulty is to find a balance between security and freedom, protection and self-determination. Through this process, the role of social engineering in the welfare state, based on humanistic ideas of solidarity, can be followed into today's emphasis on individual influence and participation. 相似文献