纤维蛋白止血敷料的生物相容性研究

目的评价纤维蛋白止血敷料的生物相容性。方法对纤维蛋白止血敷料进行如下生物学检测:细胞毒性试验(MTT法)、急性全身毒性试验、皮肤刺激试验、皮内刺激试验和溶血试验,根据标准对实验数据进行分析和评估。结果纤维蛋白止血敷料的细胞毒性分级0—1级;无急性全身毒性作用,无皮肤刺激反应、皮内刺激反应,无溶血性。结论纤维蛋白止血敷料具有良好的生物相容性。     

三种不同加压包扎方法在乳腺癌改良根治术创面的应用研究

目的探讨在乳腺癌改良根治术创面应用中最有效的加压包扎方法。方法选取150例乳腺癌改良根治术,将病例随机分为3组,每组50例。A组创面采用胸带加压包扎;B组创面采用宽绷带加压包扎;C组采用双层弹力网制成的网袋套入胸部加压包扎。通过不同加压方法对乳腺癌改良根治手术后患者的创面皮下积液、皮肤Ⅰ期愈合例数、术后平均愈合天数和拔管时间等进行分析,对比不同方法的效果。结果C组的创面皮下积液发生率、平均拔管时间、切口愈合时间均低于A、B组(P<0.05),切口I期愈合率高于A、B组(P<0.05)。结论使用双层弹力网的加压方法能均匀施压,有效地减少乳腺癌术后并发症的发生。     

Continuous Wound Irrigation in the Pig

It was demonstrated in the pig that full-thickness wounds in the skin can be continuously treated by irrigation for several days. Irrigation was accomplished through a porous, occlusively applied dressing having two ports, one for supply and one for drainage. The fluid, delivered by means of an iv set, was sucked through the inert dressing, leaving it partially saturated, and with fluid spread evenly through its pores. Particulate matter was removed along narrow paths converging on the outlet, not showing any significant diversion. The apparatus for fluid supply and drainage was arranged to move with the animal, thus eliminating the risk of obstruction of the tubes as a result oft wisting. The fluid was eliminated by one suction line, and the vacuum in the dressing maintained by another. This allowed the suction to be adjusted to a level near the atmospheric pressure.     

Wound dressings: principles and practice

Wound dressings have increased in efficacy and number as the scientific understanding of wound healing has improved. However current practice is governed by expert opinion as high-quality studies comparing the effectiveness of different dressings are lacking. Surgeons are regularly involved in wound management, therefore require a good understanding of the properties and uses of different wound dressings. By having a firm grasp of the pathophysiology that underlies the wound-healing process a surgeon can make informed decisions about how best to manage a patient. An overview of optimal conditions for healing and the assessment of wounds is provided here. Dressings and their modes of action are discussed to provide guidance for their use in different wounds.     

湿性愈合疗法治疗下肢静脉性溃疡32例

目的探讨湿性愈合疗法与干性愈合疗法在下肢静脉性溃疡处理中的疗效。方法采用随机分组法，将60例患者分为试验组（32例）和对照组（28例），观察两种疗法的治疗效果。结果采用湿性愈合疗法对下肢静脉性溃疡处理，疗效满意，患者康复时间缩短1／3，费用较千性愈合疗法明显减少。结论湿性愈合疗法优于传统的干性愈合疗法，值得推广。     

藻酸盐敷料治疗褥疮的疗效观察及护理

目的:观察藻酸盐敷料治疗褥疮的效果。方法:10例溃疡期褥疮患者采用常规清洗消毒方法加用藻酸盐敷料和标准型溃疡贴进行局部换药,观察溃疡情况。结果:用藻酸盐敷料加标准型溃疡贴治疗溃疡期褥疮,溃疡愈合时间短,换药时疼痛减轻。结论:藻酸盐敷料治疗褥疮有效,溃疡愈合时间缩短。     

石膏夹板配合纸圈外固定治疗内收型肱骨外科颈骨折

目的：观察石膏夹板配合纸圈外固定治疗内收型肱骨外科颈骨折的疗效。方法：先复位，后固定。口服活血化瘀、消肿止痛药加功能锻炼。结果：该方法固定效果好，操作简便，有助于减轻患者疼痛刺激，无并发症，疗效可靠。结论：石膏夹板配合纸圈外固定方法是治疗内收型肱骨外科颈骨折的简便、可靠、方便的方法之一。     

几种烧伤敷料的研究进展

敷料在治疗烧伤引起的皮肤组织缺损中，已得到广泛应用。现对几种烧伤敷料，就其目前的类型、结构、性能指标及研究现状，作一简单的综述。为临床应用提供一定的理论基础。     

The pH changes of four different calcium hydroxide mixtures used for intracanal medication

The purpose of this study was to determine the pH values of calcium hydroxide mixtures in combination with either distilled water, two different local anaesthetic solutions or physiological saline solution, which are commonly used as a dressing materials during endodontic treatment. The pH of each vehicle prior to mix with calcium hydroxide and subsequently each prepared combination was determined using a digital pH meter. The pH measurements were determined at 3 min, 10 min, 1 h, 24 h, 48 h and 7 days. The results of this study indicated that four different water-based vehicles demonstrated similar pH changes range within pH 11-12 when mixed with calcium hydroxide.     

一种海绵状伤口敷料的制备及结构性能的研究

采用冷冻壳聚糖-明胶共混液诱导相分离的方法，制成多孔性、亲水性、透气性良好的海绵状伤口敷料。通过对海绵体敷料结构及性能的研究，结果表明：壳聚糖与明胶分子之间形成了较强的氢键，壳聚糖中的-NH2与明胶中的-COOH发生酰胺化反应，说明壳聚糖的羟基与交联剂之间有反应发生，其反应历程有待进一步研究。由此可认为两种物质达到分子水平的分散，具有良好的相容性。