Dang Shen [Codonopsis pilosula (Franch.) Nannf] Herbal Formulae for Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta‐analysis

This systematic review and meta‐analysis assessed the efficacy and safety of Dang shen [Codonopsis pilosula (Franch.) Nannf., root] formulae for the treatment of chronic obstructive pulmonary disease (COPD). English and Chinese databases were searched, and 48 randomized controlled trials were included. Dang shen formulae improved lung function forced expiratory volume in 1 s compared with conventional pharmacotherapy (CP) [mean difference (MD) 0.22 L, 95% confidence interval (CI) 0.13–0.31, p < 0.001, I² = 5%] and quality of life (St. Georges Respiratory Questionnaire) compared with placebo (MD ?7.19, 95% CI ?10.82 to ?3.56, p < 0.001, I² = 0%) and when combined with CP versus CP (MD ?9.05, 95% CI ?12.72 to ?5.38, p < 0.001, I² = 89%). Dang shen formulae also increased distance walked in 6 min when combined with CP versus CP alone (MD 51.43 m, 95% CI 30.06–72.80, p < 0.001, I² = 27%) and reduced frequency/days with COPD exacerbations. Risk of bias was evaluated using the Cochrane tool. Methodological shortfalls were identified. Adverse events were low and not different between intervention and control groups. Thirty‐three events were reported, including gastrointestinal upset, dry mouth, and insomnia. Dang shen formulae appear to improve some aspects of the included COPD outcomes. However, owing to methodological flaws, the current evidence is inadequate to support the routine use of Dang shen formulae outside of Chinese medicine practice. However, these results justify further investigation. Copyright © 2014 John Wiley & Sons, Ltd.     

《辅行诀》大补肾汤加减方治疗眩晕临床观察

目的:采用随机对照试验的方法观察《辅行诀五脏用药法要》中大补肾汤加减方治疗肾阴虚型眩晕的临床疗效及安全性。方法:将57例肾阴虚型眩晕的患者按随机数字表随机分为中药治疗组(大补肾汤加减方)29例及西药治疗组(甲磺酸倍他司汀片)28例,2组患者在治疗期间暂停服用其他具有缓解晕眩或镇静作用的药物,2组治疗疗程为2 w。2组患者治疗前后分别依据自己的症状表现填写眩晕临床症候评价量表及眩晕评定量表评分系统(DARS),分别得出眩晕症状评分及病情严重程度评分后,运用SPSS 19.0软件进行统计学分析,以评定疗效。结果:中药治疗组患者总有效率明显高于西药对照组,治疗后患者的眩晕症候评分水平明显下降。结论:大补肾汤加减方可以显著缓解患者的眩晕症状,有助于从多方面提高患者的生活质量。     

针药联合治疗围绝经期烘热的临床疗效分析

目的：探讨针刺联合中药治疗阴虚火旺型围绝经期烘热症状的临床疗效及安全性。方法：采用随机平行对照的试验方法,治疗组采用清心滋肾汤联合针刺治疗,对照组予清心滋肾汤治疗。将两组综合疗效及治疗前后患者平均24小时烘热积分、性激素水平进行对比观察,并记录不良事件。结果：治疗组总有效率为80.65%,对照组为65.52%,两组间疗效有明显差异(P<0.05)。两组治疗后平均24小时烘热积分均明显下降,且治疗组优于对照性(P<0.05),治疗3个月后随访,治疗组患者的平均24小时烘热积分低于对照组（P<0.05）。两组均可升高E2水平,降低FSH、LH水平,但治疗组在改善FSH、LH水平方面优于对照组(P<0.05),3个月后随诊,治疗组E2水平高于对照组,治疗组FSH、LH水平下降幅度较对照组明显(P<0.05)。结论：针药联合对阴虚火旺型围绝经期烘热患者的治疗效果优于单用中药组,且维持时间长,不易复发。     

论中医“精”“神”一体观

中医学根植于中国传统文化,以"看病的人"为主导思想,将人视为具有自然物质属性与精神文化属性的统一体,其"以精为体,以神为主"的精神一体观贯穿始终,故文章首先从中医学的角度梳理精与神的基本概念,分别从积精全神及守神固精两方面论证"精化气生神,神驭气统精"的"精""神"一体观。再深入中国传统文化层面,以道家的无为思想,经内证实修,"炼精化气,炼气化神",将生命的形而上(神、道)与形而下(精、气)融为一体,达到精神与肉体的和谐与自由。最后从科学发展的角度探讨精与神一体的生物电生理机制,构筑精—神相互转化的生命模型假说,并从物质—能量—信息的层面讨论人的物质、精神属性的统一,提出未来融文化与科学于一体的医学发展趋势。     

中药内服配合坐浴疗法治疗肛门瘙痒症疗效观察

目的：观察中药内服配合坐浴治疗肛门瘙痒症的疗效。方法：将286例笔者分为3种类型,其中风热郁结型以凉风清风散加减,风湿夹热型以龙胆泻肝汤加减,血虚生风型以当归饮子加减,均配合中药坐浴。结果：286例患者痊愈220例,有效66例,有效率100%。结论：中药内外结合治疗肛门瘙痒症,疗效显著。     

参附注射液对兔内毒素休克肺损伤的保护作用

用兔内毒素（ＥＴ）休克模型，对平均动脉压（ＭＡＰ）及支气管肺泡灌洗液（ＢＡＬＦ）中蛋白含量及吞噬细胞胞（ＰＡＭ）变化进行观测，探讨参附注射液（ＳＦ）对兔内毒素休克肺损伤的作用。结果：ＥＴ＋ＳＦ组ＭＡＰ虽下降，但２ｈ后开始上升，至６ｈ基本恢复正常，其与ＥＴ组比，Ｐ〈０．０５，与假手术组比，ＥＴ２ｈ后差异无显著性；对ＢＡＬＦ中细胞总数和ＰＭＮ，ＥＴ＋ＳＦ组与ＥＴ组比较，差异显著；蛋白定量，ＥＴ＋ＳＴ组