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71.
Patricia Nicole Wiegele Iyad Kabar Laura Kerschke Christopher Froemmel Anna Hüsing-Kabar Hartmut Schmidt Elena Vorona Richard Vollenberg Phil-Robin Tepasse 《Emerging infectious diseases》2021,27(5):1353
Limited information is available on the clinical course of outpatients with mild coronavirus disease (COVID-19). This information is critically important to inform public health prevention strategies and to provide anticipatory guidance to patients, primary care providers, and employers. We retrospectively assessed the daily prevalence of symptoms in 313 COVID-19 outpatients for the first 20 days of illness. Generalized estimating equations were used to assess the probability of symptom occurrence over time. Fatigue (91%), cough (85%), and headache (78%) were the most common symptoms and occurred a median of 1 day from symptom onset. Neurologic symptoms, such as loss of taste (66%) and anosmia (62%), and dyspnea (51%) occurred considerably later (median 3–4 days after symptom onset). Symptoms of COVID-19 are similar to those of other respiratory pathogens, so symptomatic patients should be tested more frequently for severe acute respiratory syndrome coronavirus 2 during influenza season to prevent further spread of COVID-19. 相似文献
72.
We report mean severe acute respiratory syndrome coronavirus 2 serial intervals for Montana, USA, from 583 transmission pairs; infectors’ symptom onset dates occurred during March 1–July 31, 2020. Our estimate was 5.68 (95% CI 5.27–6.08) days, SD 4.77 (95% CI 4.33–5.19) days. Subperiod estimates varied temporally by nonpharmaceutical intervention type and fluctuating incidence. 相似文献
73.
Young June Choe Eun Hwa Choi Jong Woon Choi Byung Wook Eun Lucy Youngmin Eun Yae-Jean Kim Yeo Hyang Kim Young A. Kim Yun-Kyung Kim Ji Hee Kwak Hyuk Min Lee Hyunju Lee Joon Kee Lee June Dong Park Eun-Jin Kim Young Joon Park Jin Gwack Sang Won Lee 《Emerging infectious diseases》2021,27(4):1196
A concerning development during the coronavirus disease pandemic has been multisystem inflammatory syndrome in children. Reports of this condition in East Asia have been limited. In South Korea, 3 cases were reported to the national surveillance system for multisystem inflammatory syndrome in children. All case-patients were hospitalized and survived with no major disease sequelae. 相似文献
74.
Takahisa Fujino Hidetoshi Nomoto Satoshi Kutsuna Mugen Ujiie Tetsuya Suzuki Rubuna Sato Tsuguto Fujimoto Makoto Kuroda Takaji Wakita Norio Ohmagari 《Emerging infectious diseases》2021,27(4):1243
Multiple severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants with higher transmission potential have been emerging globally, including SARS-CoV-2 variants from the United Kingdom and South Africa. We report 4 travelers from Brazil to Japan in January 2021 infected with a novel SARS-CoV-2 variant with an additional set of mutations. 相似文献
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目的 研究清热消炎宁抗冠状病毒的作用,为评价其防治冠状病毒感染提供实验依据。方法 雌雄各半的96只BALB/c小鼠随机分为对照组、模型组、连花清瘟胶囊(0.546 g/kg)组和清热消炎宁片低、中、高剂量(8.72、17.44、34.89g/kg)组,每组16只。采用ip环磷酰胺联合HCoV-229E冠状病毒感染BALB/c小鼠,建立冠状病毒感染模型,通过小鼠体质量、肺指数、病毒载量、血凝滴度、肺组织病理改变来评价清热消炎宁的治疗作用;通过ELISA检测肺泡灌洗液中白细胞介素-1β(interleukin-1β,IL-1β)、IL-4、肿瘤坏死因子-α(tumor necrosis factor-α,TNF-α)、γ干扰素(interferon-γ,IFN-γ)和血管细胞黏附分子-1(vascular cell adhesion molecule-1,VCAM-1)水平;流式细胞术检测肺组织巨噬细胞、淋巴细胞(CD3+、CD4+)及NK细胞比例;Western blotting检测肺组织Toll样受体4(Toll-like receptor ... 相似文献
78.
Amin Sadeghi Dousari Seyed Soheil Hosseininasab Fatemeh Sadeghi Dousari Masoumeh Fuladvandi Naghmeh Satarzadeh 《World Journal of Virology》2023,12(2):91-99
The coronavirus disease 2019 (COVID-19) disease was first detected in December 2019 in Wuhan, China. This disease is currently one of the most important global health problems. The novel coronavirus COVID-19 is a respiratory illness, that has caused a deadly pandemic that is spreading rapidly around the world. It is not only a respiratory system virus that causes severe lung disease, but also a systemic disease agent that can affect all systems. People with COVID-19 disease usually have respiratory signs, however, the liver disorder is not an uncommon presentation. In addition, many studies around the world have revealed that the liver is injured to various degrees in patients with severe acute respiratory syndrome coronavirus 2 disease. This review mainly focuses on the impact of COVID-19 on Liver Injury at various ages. 相似文献
79.
Zafer Tandogdu Justin Collins Greg Shaw Jennifer Rohn Bela Koves Ashwin Sachdeva Ahmed Ghazi Alexander Haese Alex Mottrie Anup Kumar Ananthakrishnan Sivaraman Ashutosh Tewari Benjamin Challacombe Bernardo Rocco Camilo Giedelman Christian Wagner Craig G. Rogers Declan G. Murphy Dmitry Pushkar Gabriel Ogaya-Pinies James Porter Kulthe Ramesh Seetharam Markus Graefen Marcelo A. Orvieto Marcio Covas Moschovas Oscar Schatloff Peter Wiklund Rafael Coelho Rair Valero Theo M. de Reijke Thomas Ahlering Travis Rogers Henk G. van der Poel Vipul Patel Walter Artibani Florian Wagenlehner Kris Maes Koon H. Rha Senthil Nathan Truls Erik Bjerklund Johansen Peter Hawkey John Kelly 《BJU international》2021,127(6):729-741
80.
《Gaceta sanitaria / S.E.S.P.A.S》2021,35(6):565-568
ObjectiveWe address the hypothesis that the extraordinary sandstorm occurred on 22-24 February 2020 might have a role in the different cumulated incidence of COVID-19 cases between the islands of Tenerife and Gran Canaria, since it obliged to reduce significantly air traffic and forced to suspend all major carnival street events in all most locations.MethodWe performed a retrospective analysis of COVID-19 cases as to 1 April 2020 according to symptoms onset, weather-related data and Carnival events in Tenerife and Gran Canaria.ResultsThe sandstorm occurred on February 22-24, 2020, forced air traffic to close, reducing the influx of tourists to the Canary Islands and suspending carnival events in most places, except in Santa Cruz de Tenerife. Cumulated incidence as to 1 April was 132.81/100,000 in Tenerife, and 56.04/100,000 in Gran Canaria.ConclusionsThe suspension of Carnival events due to the sandstorm in the Canary Islands contributed to reduce differently the SARS-CoV-2 spread in Tenerife and Gran Canaria. 相似文献