疾控中心实验室质量管理探讨

宁夏疾病预防控制中心通过建立质量管理体系,对人员、仪器设备和标准物质、样品、记录、检验报告等影响质量的因素在体系运行中实施有效控制,并不断持续改进达到有效运行的目的,使实验室管理逐步走向了正规。     

实验室管理体系的内部审核

文章参考《ISO／IEC17025实验室管理体系应用指南》及有关报道,并结合几年来参与内部审核（以下简称内审）工作的实践,就内审的目的、原则、方法、实施、作用等进行了阐述。     

出院病案护理文书终末质量检查21226份结果分析

目的探讨护理文书书写过程中的缺陷构成、产生原因和管理措施。方法对我院2007年11月-2008年10月期间归档的21226份出院病案护理文书终末质量检查结果进行统计分析。结果21226份出院病案中护理文书存在缺陷的696份（缺陷数目总计869项次）,其中体温单507项次、医嘱单216项次、护理记录单104项次、护理计划42项次,分别占总缺陷数目的58．34％、24．86％、11．97％、4．83％。结论护理文书缺陷不能完全避免,但通过加强专业培训、加强科室自查自控、加强专项检查总体控制等各环节的系统管理,可防范和降低护理文书缺陷发生率,提高护理文书书写质量。     

Patient's satisfaction with perioperative care: development, validation, and application of a questionnaire

Background: Measuring patient satisfaction after anaesthesia care is complex.The existing patient satisfaction questionnaires are limitedand omit aspects of patient satisfaction, such as professionalcompetence, information provision, service, and staff–patientrelationship. The aim of our study was to develop a valid andreliable self-reported multidimensional questionnaire assessingpatient satisfaction that included these issues. Methods: The development of the Leiden Perioperative care Patient Satisfactionquestionnaire (LPPSq) was as follows: expert consultation, constructionof the pilot questionnaire, pilot study, statistical analysisof the results of the pilot study (validity, reliability, andfactor analysis), compilation of the definitive questionnaire,main study, and repeated statistical analysis (validity, reliability,and factor analysis). The overall patient satisfaction is expressedby the mean satisfaction score. Results: Three hundred and eighty-two patients consented to participatein the study; 80.4% of the patients (n=307) completed the questionnaire.The LPPSq isolated three dimensions: information (Cronbach’s=0.82), fear and concern (Cronbach’s =0.69), and staff–patientrelationship (Cronbach’s =0.94). Patient satisfactionwith perioperative care was not directly dependent on the outcomesof anaesthesia but how patients were approached and the amountof information they received. Age (P=0.001), gender (P=0.001),work situation (P=0.003), and specialty (P=0.017) were the characteristicsmost influencing patient satisfaction. Conclusions: We developed the LPPSq questionnaire to measure patient satisfactionwith perioperative care, of which anaesthesia care is an importantelement. In this study, information provision and the relationshipbetween staff and patient were the major determinants of patientsatisfaction.     

Setting priorities for improving the preoperative assessment clinic: the patients' and the professionals' perspective

BACKGROUND: The quality of the preoperative assessment clinic (PAC) is determined by many factors. Patients' experiences are important indicators, but often overlooked. We prepare to set priorities to improve the PAC by obtaining detailed patients' feedback on the quality of the PAC, and establishing the value patients and professionals attach to different care aspects, using the Patient Experiences with the Preoperative Assessment Clinic questionnaire. METHODS: The PAC's standard of service was determined for five care aspects (dimensions), using patients' feedback. The importance of a dimension to patients was determined by calculating the effects of the dimensions on patients' overall appraisal. In addition, professionals were asked to rate the importance of the different care aspects. RESULTS: Patients had the most positive experiences with the nurse, and the least positive experiences with waiting. However, waiting was least important to patients. When combining the PAC's standard of service with the value given to the dimensions by patients and professionals separately, we found in both instances that waiting was in greatest need of improvement. This was followed by reception, the anaesthetist, remaining experiences, and finally the nurse. CONCLUSIONS: Quality improvement of the PAC can be achieved by obtaining patients' feedback on the quality, determine a PAC's standard of service, recognize service areas that require improvement, and identify actions appropriate to bring about improvement. The value patients and professionals attach to different aspects of care can then be used to prioritize improvements.     

Using tailored telephone counseling to accelerate the adoption of colorectal cancer screening

BACKGROUND: Few interventions to increase colorectal cancer screening have used a stage of change model to promote screening adoption. None have used computer-assisted tailored telephone counseling calls. This study's purpose was to implement and evaluate stage-based computer-assisted tailored telephone counseling to promote colorectal cancer screening in a primary care population. METHODS: This randomized controlled trial used a two-stepped intervention that included a mailed booklet on colorectal cancer screening followed by computer-assisted telephone counseling that was based on the Precaution Adoption Process Model. Chart audit was used to document completion of colonoscopy, sigmoidoscopy or fecal occult blood testing. RESULTS: Record audits were completed on 2,474 (88%) of the 2,817 eligible participants. There was no significant difference in the frequency and nature of the screening tests completed in the study arms. In a sub-analysis, stages of adoption were evaluated pre- and post-telephone counseling. Over half those receiving counseling reported a change in stage towards screening adoption. CONCLUSION: Overall, the intervention did not increase colorectal screening compared to control. Two possible reasons for the absence of a screening effect include: (a) the focus of the protocol on education for most patients rather than motivation, and (b) the requirement that patients interested in screening seek further information and a referral on their own from their providers. While those receiving telephone counseling improved their stage of adoption, we cannot rule out selection bias. Stronger physician recommendation to speak with the counselors could improve call acceptance. Future colorectal screening should address these weaknesses.     

药品生产企业如何选择物料供应商

本文从药品生产的GMP管理角度 ,阐述了物料管理在药品生产企业生产活动中的重要意义 ,并提出了选择物料供应商的方法和一些切实可行的对物料供应商进行评审的程序。     

Assessing the outcomes of total knee replacement

Abstract: The past few years have seen a growth of interest in outcome measurement in a variety of settings including audit, health care management and commissioning – besides the traditional applications in research work. This paper reports on a study of the outcomes of total knee replacement in an acute hospital where the outcomes were studied as part of an audit process. The outcome measures used included clinical and symptomatic measures as well as generic health status scales. The initial study in one hospital was expanded to include a number of others in the same region and a comparative database of outcomes developed. Examples of the results are shown. The technical measures using knee scores and general health status measure show significant improvement from pre-operatively to 3 months later. This improvement was maintained up to the 1-year follow-up on both measures. Although the information systems for collecting and measuring outcomes has been successful, the ability of such measures to lead to behavioural change has been limited. The problems in using outcome measures are discussed in particular in the context of an audit within hospitals, and for purchasing agencies.     

An Audit of The Royal College of Ophthalmologists Strabismic Amblyopia Treatment Protocol: A Departmental Review

Introduction: Children presenting with strabismus and mixed (anisometropic/strabismic) amblyopia are managed by a local protocol as per guidelines from the Royal College of Ophthalmologists. Decisions regarding intervention for occlusion are currently delayed until a 22 week review allowing for refractive adaptation, with intermediate reviews at 6 and 14 weeks. Purpose: The purpose of this audit was to determine adherence to the protocol and the benefit of the 14 week review. Materials and Methods: We performed a prospective data collection of all children attending the orthoptic department with strabismus without pathology, both with and without unequal vision, from October 2007 to July 2008 managed using the protocol. Results: 26 patients were eligible. Mean age at presentation was 3.3 years (1.4 to 6.5). Cycloplegic spherical equivalent (SE) mean was 2.6 dioptres (?2.25 to +7.25). Five patients failed to comply with the protocol; one patient was listed surgery, four patients commenced premature occlusion. At presentation 8 patients had equal vision (defined as < 0.1 logMAR difference) between the two eyes or would only perform BEO vision, by week 14, over 60% were found to have a difference in vision between the eyes, despite refraction correction (mean 0.4 logMAR, range 0 to 1.4 logMAR). In a subgroup of patients (n = 8 at 6 weeks) with a small discrepancy of vision between the eyes (0.1 to 0.5 logMAR) there was no progressive worsening of vision during the period of observation and 50% of patients improved spontaneously, although two patients were lost to follow up. In the subgroup (n = 10 at 6 weeks) with a large discrepancy between the eyes (> 0.5 logMAR), all patients ultimately required occlusion, and there was minimal improvement in only three patients. Conclusion: Recorded vision at 6 weeks is more informative for making treatment decisions than that recorded at presentation. The 14 week review confers no benefit to those with reliable and improving visual acuity. Those patients presenting with a large discrepancy in visual acuity do not improve after 14 weeks and we feel that these patients could be occluded at 6 weeks. We propose a new algorithm for the treatment of this patient group.