针药结合治疗糖尿病胃轻瘫研究进展

糖尿病胃轻瘫(DGP)是糖尿病患者中发病率较高的慢性胃肠道并发症,其发病原因及机制十分复杂,目前临床尚无针对性的治疗方案,其治疗一直为临床所重视。目前研究表明,针药结合较单纯用药及单纯针灸具有明显优势,但大多属于临床小样本观察,机制尚不明确。     

Acupuncture and massage combined with rehabilitation therapy for hemiplegia after stroke: A protocol for systematic review and meta-analysis

Background:The purpose of this study was to evaluate the effectiveness and safety of acupuncture and massage combined with rehabilitation in the treatment of hemiplegia after stroke.Methods:To collect relevant literature, we will research following databases: Medicine, PubMed, Embase, Web of Science, Cochrane Library, China National Knowledge Infrastructure, Wan-Fang Database, Chongqing VIP Chinese Science and Technology Periodicaols Database, and China Biomedical Database; the time is from its creation to May 2021, and the language is limited to Chinese and English. In addition, we will retrieve other literature resources, including the Chinese Clinical Trial Register and conference articles. Two reviewers will independently complete the literature screen and data extraction and quality assessment of the included studies will be independently completed by two other researchers. The primary outcomes included the Modified Ashworth scale and the simplified Fugl-Meyer Assessment scale. The Modified Barthel Index, the China Stroke Scale, and adverse reactions as secondary outcomes were assessed. RevMan V.5.4.1 software will be used for meta-analysis, and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) will be used to assess the quality of evidence.Results:This systematic review will provide a high-quality synthesis to evaluate the efficacy and safety of acupuncture and massage combined with rehabilitation in the treatment of hemiplegia after stroke, providing a reference for the safe and effective treatment of hemiplegia after stroke.Conclusion:This study provides evidence that acupuncture and massage combined with rehabilitation therapy is effective.Ethics and dissemination:The protocol of the systematic review does not require ethical approval because it does not involve humans. This article will be published in peer-reviewed journals and presented at relevant conferences.Systematic review registration:INPLASY202210026.     

针灸对海洛因复吸大鼠脑组织多巴胺、5-羟色胺的影响

目的探讨针灸干预海洛因复吸的作用机制。方法采用间断性递增量肌肉注射海洛因的方法复制海洛因复吸大鼠模型,观察针灸对海洛因复吸大鼠条件性位置偏爱（conditional position preference,CPP）的行为学改变及脑组织多巴胺（dopamine,DA）、5-羟色胺（5-hydroxytryptamine,5-HT）含量变化的影响。结果针灸能防止海洛因复吸大鼠体质量的下降（P〈0.01）,显著延长海洛因复吸大鼠在暗箱的停留时间（P〈0.01）,显著降低海洛因复吸大鼠脑组织DA和5-HT含量（P〈0.01）。结论抑制脑组织DA、5-HT的释放,降低对海洛因用药行为有关环境的依赖行为,可能是针灸干预海洛因复吸的作用机制之一。     

Incidence Rate of Bee Venom Acupuncture Related Anaphylaxis: A Systematic Review

Background: Bee venom acupuncture (BVA) is an effective treatment method for various diseases. Bee venom, however, can cause adverse effects, even rarely including life-threatening anaphylaxis, so safety-related evidence is required. In this study, we systematically estimated the incidence rate of anaphylaxis in response to BVA. Methods: We searched eight databases (MEDLINE (Pubmed), EMBASE, Cochrane Central Register of Controlled, KISS, KMBASE, Koreamed, OASIS, and NDSL) and systematically reviewed the articles that met the inclusion/exclusion criteria. Results: Among 225 potentially relevant articles, 49 were selected for this study. The overall incidence rate of anaphylaxis in response to BVA was 0.045% (95% CI 0.028–0.062). Women (0.083%, 95% CI 0.010–0.157) showed a higher incidence rate than men (0.019%, 95% CI −0.018 to 0.055), while the incidence for patients who had a skin test conducted (0.041%, 95% CI 0.011–0.072) was not significantly different compared to that obtained for patients for which there was no information about a skin test (0.047%, 95% CI 0.026–0.067). The publication year affected the incidence rate: it was highest before 1999 (1.099%, 95% CI −1.043 to 3.241), lower between 2000 and 2009 (0.049%, 95% CI 0.025–0.073), and lowest between 2010 and 2021 (0.037% 95% CI 0.014–0.060). Conclusions: In this study, we provide reference data about risk size and factors of BVA-related anaphylaxis, which is essentially required for BVA application in clinics.     

眼针与普通针灸治疗腹泻型肠易激综合征理论异同研究

眼针是由著名老中医彭静山教授独创的一种微针疗法。眼针是以五轮八廓学说为基础,普通针灸是以经络学说为基础的,两种治疗方法的理论基础的出发角度不同,但追本溯源,还是以中医理论思想作为指导。     

针灸配合养阴清肺汤治疗慢性咽炎39例

[目的]观察针灸合养阴清肺汤佐治慢性咽炎的临床疗效。[方法]将门诊120例慢性咽炎患者随机分为三组,中医药组41例,针灸配合养阴清肺汤治疗,连服2周。西医药组40例,口服西地碘片,1.5mg次/,3次/日;庆大霉素8万U,地塞米松10mg,α-糜蛋白酶4000U超声雾化吸入,治疗2周。中西结合组39例在西医治疗的基础上加针灸及中药养阴清肺汤。[结果]中西结合组总有效率为94.9%,中医药有效率为73.2%,西医药组67.5%,三组都无明显毒副作用。中西结合组与另两组比较有显著差异（P〈0.01）。[结论]针灸配合养阴清肺汤佐治慢性咽炎,疗效确切。     

火罐内压力变化及罐内负压对毫针进针深度影响观察

本研究旨在观察罐内负压与时间、罐内负压与毫针出针长度的关系。在肾俞穴部位燃拔火罐20 min,通过压力传感器用高速生理记录仪记录罐内负压变化情况。在肾俞穴行毫针刺,以不同负压加拔火罐,测量拔罐前后毫针进针长度变化。观察发现:(1)罐内负压的绝对值与拔罐时间呈逐渐下降趋势,在拔罐20 min后明显变小(P0.05);(2)罐内负压使毫针向外运动(出针),相同压力下,男性出针长度大于女性(P0.01)。罐内负压的大小以及性别可影响毫针出针长度。     

针药合用对大鼠局灶性脑缺血预后的影响

目的研究针药合用对脑缺血大鼠的治疗作用。方法阻断大鼠一侧大脑中动脉(MCA)造成局灶性脑缺血模型(MCAO),观察针药合用对神经病学症状、被动性条件反向、血液流变性、脑梗死面积及脑组织病理学的影响,并与单纯针刺和单纯药物组比较。结果3组均能改善脑缺血大鼠神经症状,提高学习记忆能力,降低血液黏度,缩小脑梗死面积,促进坏死灶内血管和胶质细胞增生修复,减少脑组织水肿和炎性细胞浸润。结论针药组在提高学习记忆能力及降低血液黏度方面明显优于针刺和药物组。     

腹部手术后促进胃肠功能恢复的临床研究

介绍了腹部手术后促进胃肠功能恢复的临床研究．重点阐述了单纯用药、针刺治疗、穴位注射及按摩、应用胃肠起搏器、早期肠内营养、早期锻炼等方法。