齐刺阳陵泉对胆绞痛豚鼠IL-1β、IL-6的影响

目的:观察齐刺胆的下合穴阳陵泉对胆绞痛豚鼠血清白介素1β(1L-1β)和白介素6(IL-6)的影响以及镇痛效果。方法:将60只成年雄性豚鼠随机分为空白组(10只)、模型组(10只)、药物组(20只)和针刺组(20只),空白组正常饲养,模型组、药物组、针刺组造模成功后,药物组给予双氯芬酸钠盐酸利多卡因注射液腹腔注射,针刺组取双侧阳陵泉穴进行齐刺,每日1次。治疗5天后于腹主动脉采取新鲜血液,匀浆、离心后分离血清,采用酶联免疫吸附法(ELISE)测定IL-1β,IL-6的含量。结果:①与空白组比较,模型组豚鼠血清IL-1β、IL-6含量明显升高,差异有非常显著意义(P0.01);②与模型组比较,药物组、针刺组血清IL-1β、IL-6含量明显偏低,差异有非常显著意义(P0.01);与药物组比较,针刺组IL-1β、IL-6含量明显偏低,差异有显著意义(P0.05)。结论:针刺治疗对胆绞痛豚鼠有一定的镇痛作用,且针刺疗效明显优于药物组。     

益智膏治疗小儿智力低下34例临床观察

[目的]观察应用益智膏配合针刺改善肾精不足型智力低下患儿智能水平的临床疗效。[方法]将68例入组患儿按照随机数字表法分成治疗组和对照组,治疗组34例给予服用益智膏、针刺、康复训练,对照组34例给予针刺、康复训练;采用中国韦氏幼儿、儿童智力量表进行评分,应用尼莫地平法计算智商(IQ)分值提高率。[结果]益智膏配合针刺治疗肾精不足型智力低下有效,临床总体疗效优于对照组,两组比较具有统计学意义(P0.05)。[结论]益智膏配合针刺治疗肾精不足型智力低下临床疗效确切。     

Complex Regional Pain Syndrome Type 1 Relieved by Acupuncture Point Injections with Placental Extract

This is a case report of a female patient who developed complex regional pain syndrome in the left upper limb after a traumatic injury to the distal part of the left forearm. The pain was immediate and resistant to oral analgesics and continued transcutaneous electrical nerve stimulation. Five months after the injury, the patient presented to our clinic with severe pain, swelling, redness, cold sensation of the left hand, and loss of function from the left hand up to the left shoulder. Acupuncture points LI5, LU2, SI10, HT1, GB21, and SI11 (which are localized in the joints or in the muscles responsible for the movement of the left upper limb) were selected for the application of the placental extract. Injection of placental extract into the acupuncture points resulted in dramatic pain relief, swelling remission, motor recovery, temperature normalization, and disappearance of redness in this patient with complex regional pain syndrome type 1.     

足针配合项针治疗重型脑卒中的临床疗效观察

目的：观察足针配合项针治疗重型脑卒中的临床疗效。方法：足针疗法治疗重型脑卒中，有吞咽困难或失语患者配合项针治疗。结果：治疗后总有效率为95％。结论：足针配合项针治疗脑卒中疗效显著。     

Complementary Acupuncture Treatment Increases Cerebral Metabolism in Patients with Parkinson's Disease

We used positron emission tomography (PET) and the 18-flourodeoxyglucose tracer to study cerebral effects of complementary acupuncture in Parkinson's disease. Five patients received scalp-acupuncture and Madopa, while the other five had Madopa only. PET scans before and after 5 weeks of complementary acupuncture treatment show increased glucose metabolisms in parietal, temporal, occipital lobes, the thalamus, and the cerebellum in the light-diseased hemisphere, and in parietal and occipital lobes of the severe-diseased hemisphere. No changes were observed in the Madopa-only group. Acupuncture in combination with Madopa may improve cerebral glucose metabolism in Parkinson's disease.     

中国针灸腧穴与尼泊尔传统医学生命点的对比研究

中国和尼泊尔的传统医学理论体系都有悠久的历史, 且两者的治疗手段都源自相同的哲学和理论基础。在使用自然疗法治疗疾病的过程中, 两种医疗体系均提出了人体的重要位置点的理论, 即中医的经络腧穴理论和尼泊尔传统医学中的生命点理论。初步将中国针灸腧穴以及尼泊尔传统医学中的生命点的进行对比研究, 为今后两者的结合应用提供依据。     

Acupuncture for diabetic neurogenic bladder: A protocol for systematic review and meta-analysis

Background:Diabetic neurogenic bladder (DNB) is one of the common complications of diabetes mellitus, which has a high prevalence rate. Some research suggested that acupuncture can improve the clinical symptoms of diabetic neurogenic bladder patients, but there is no systematic review or meta-analysis to assess this therapy. Therefore, this study aims to explore the effectiveness and safety of acupuncture for patients with DNB.Methods:In this study, we will search for electronic databases including the Cochrane Library, Web of Science, PubMed, MEDLINE, EMBASE,China National Knowledge Infrastructure (CNKI), Wan-Fang, and Baidu Scholar Database from inception to December 2020. We will select randomized controlled trials that have been published in English or Chinese related to acupuncture for DNB. Selection of study, extraction of data, and assessment of study quality will be performed independently by 2 researchers, and we will use Revman 5.3 software which is provided by Cochrane assistance network, to perform the data analysis.Results:This study will provide evidence of the effectiveness and safety of acupuncture for DNB.Conclusion:This study will clarify whether acupuncture is an effective treatment for DNB, and will also provide a reference for clinical practice and guidelines development.     

Effectiveness and safety of warm needle acupuncture for sciatica: A protocol for systematic review and meta-analysis

Background:Sciatica is a syndrome characterized by sciatic nerve path and distribution area pain. Many kinds of literature reported the definite effect of warm needle acupuncture (WNA) on sciatica. However, there is no systematic review or meta-analysis on WNA for sciatica. Therefore, this study will design a protocol to comprehensively and systematically evaluate the effectiveness and safety of WNA on sciatica.Methods:The two researchers in this study will search the electronic database for randomized controlled trials, (RCTs) of WNA on sciatica, The databases we will search include PubMed, EMBASE, Cochrane Library, Web of Science, Chinese national knowledge infrastructure (CNKI), China Science and Technology Journal Database (VIP), Wanfang Database, and Chinese biomedical literature database (CBM). Review Manager 5.4 software and Cochrane risk bias tool will be us used for data analysis and to evaluate research quality. The main clinical indicators will include visual analogue scale (VAS) and Oswestry Disability Index (ODI).Results:This study will evaluate the efficacy and safety of WNA for sciatica.Conclusion:This study will provide a reliable scheme for objectively and comprehensively evaluating the efficacy and safety of WNA on sciatica.Trial registration number:INPLASY2020110074     

The study on the clinical effectiveness and safety of traditional Chinese medicine acupoint catgut embedding guided by musculoskeletal ultrasound in the treatment of nerve root sciatica: A protocol for systematic review and meta-analysis of randomized controlled trials

Background:Nerve root sciatica (NRS) is a common orthopedic disease, which usually occurs between 20 and 40 years of age, and the incidence rate is increasing year by year and is being younger. The disease has no special effect of treatment, clinically generally taking the symptomatic treatment, such as taking short-term glucocorticoids, sedatives, analgesics, and so on. Long-term use of drugs will adversely affect the patient''s gastrointestinal tract, liver, and kidney function. The surgical treatment has a high risk of surgery, high cost, side effects, and other problems, so the choice of treatment method has always been a difficult problem in clinical and scientific research. The study shows that 90% of patients with sciatica can be cured by non-surgical treatment, so conservative therapy is often used in the treatment of sciatica, traditional Chinese medicine treatment methods in the treatment of NRS has been widely used, which has achieved good results, but there is no evidence of evidence-based medicine. Therefore, this study uses systematic evaluation to conduct the scientific evaluation of the clinical effectiveness and safety of traditional Chinese medicine acupoint catgut embedding guided by musculoskeletal ultrasound in the treatment of NRS, and provide evidence-based medical evidence support for the treatment of NRS.Methods:Using the computer to retrieve the PubMed, ScienceDirect, Web of Science, Embase, Cochrane Library, CNKI, VIP, WANFANG Database, and CBM. Using the subject words and terminology words to retrieve the Chinese-English database and retrieve a randomized controlled study on the clinical effectiveness and safety of traditional Chinese medicine acupoint catgut embedding guided by musculoskeletal ultrasound in the treatment of NRS, and the range of search time is January 1990 to January 2021. The searched literature is screened and evaluated by two researchers respectively according to the inclusion and exclusion criteria. If there is disagreement, discussing it with the third researcher to determine the final inclusion of the literature. Using the RevMan 5.3 software to conduct the meta-analysis.Results:This study will compare the effectiveness and safety of traditional Chinese medicine acupoint catgut embedding guided by musculoskeletal ultrasound in the treatment of NRS.Conclusion:The results of this study will be published in internationally influential academic journals to provide evidence-based medical evidence for the clinical effectiveness and safety of traditional Chinese medicine acupoint catgut embedding in the treatment of NRS.Ethics and dissemination:This study does not involve specific patients, and all research data comes from publicly available professional literature, so an ethics committee is not required to conduct an ethical review and approval of the study.OSF registration number:DOI 10.17605/OSF.IO/Q492E.     

Acupuncture and related therapies for poststroke insomnia: A protocol for systematic review and network meta-analysis

Objective:To compare and evaluate the clinical effects on patients with poststroke insomnia of various acupuncture and acupuncture-related therapies.Methods:In order to analyze the direct and indirect evidence from related studies, we used network meta-analysis (NMA). In order to collect randomized controlled trials (RCTs) of acupuncture and related therapies in the treatment of poststroke insomnia, 3 English and 4 Chinese databases were searched. After 2 researchers independently screened the literature, extracted the information, and assessed the probability of bias in the included studies, the data was analyzed using Stata15.0 and WinBUGS1.4.3 software.Results:Based on the existing data, the pros and cons of different acupuncture-related therapies are compared extensively, the effectiveness of different acupuncture-related therapies is ranked compared to drugs with hypnotic effect in poststroke insomnia care, and the best methods or combinations of acupuncture intervention are summarized.Conclusion:This study will provide new evidence for the safety and effectiveness of acupuncture-related therapies in the treatment of poststroke insomnia, and may be helpful for clinicians, poststroke insomnia patients, and clinical guideline makers to choose the optimal combination of acupuncture for the treatment of poststroke insomnia.Registration Number:INPLASY202120028.