全文获取类型
收费全文 | 350116篇 |
免费 | 23234篇 |
国内免费 | 7899篇 |
专业分类
耳鼻咽喉 | 4118篇 |
儿科学 | 9826篇 |
妇产科学 | 6582篇 |
基础医学 | 28233篇 |
口腔科学 | 8198篇 |
临床医学 | 39154篇 |
内科学 | 43576篇 |
皮肤病学 | 4597篇 |
神经病学 | 19926篇 |
特种医学 | 8036篇 |
外国民族医学 | 33篇 |
外科学 | 37797篇 |
综合类 | 52264篇 |
现状与发展 | 13篇 |
一般理论 | 32篇 |
预防医学 | 36544篇 |
眼科学 | 5328篇 |
药学 | 31630篇 |
476篇 | |
中国医学 | 31255篇 |
肿瘤学 | 13631篇 |
出版年
2024年 | 1152篇 |
2023年 | 5705篇 |
2022年 | 10124篇 |
2021年 | 13794篇 |
2020年 | 12885篇 |
2019年 | 18540篇 |
2018年 | 16200篇 |
2017年 | 13235篇 |
2016年 | 10719篇 |
2015年 | 9948篇 |
2014年 | 20450篇 |
2013年 | 22108篇 |
2012年 | 18706篇 |
2011年 | 20265篇 |
2010年 | 16250篇 |
2009年 | 14944篇 |
2008年 | 14576篇 |
2007年 | 15084篇 |
2006年 | 13140篇 |
2005年 | 11355篇 |
2004年 | 9251篇 |
2003年 | 8087篇 |
2002年 | 6356篇 |
2001年 | 5709篇 |
2000年 | 4709篇 |
1999年 | 4084篇 |
1998年 | 3321篇 |
1997年 | 3157篇 |
1996年 | 2741篇 |
1995年 | 2632篇 |
1994年 | 2536篇 |
1993年 | 2023篇 |
1992年 | 2060篇 |
1991年 | 1769篇 |
1990年 | 1563篇 |
1989年 | 1397篇 |
1988年 | 1334篇 |
1985年 | 3816篇 |
1984年 | 4816篇 |
1983年 | 3356篇 |
1982年 | 3823篇 |
1981年 | 3567篇 |
1980年 | 3174篇 |
1979年 | 2927篇 |
1978年 | 2551篇 |
1977年 | 1917篇 |
1976年 | 2158篇 |
1975年 | 1639篇 |
1974年 | 1436篇 |
1973年 | 1278篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
61.
Jay Magaziner Eleanor M. Simonsick T. Michael Kashner J. Richard Hebel 《Journal of clinical epidemiology》1988,41(11)
The present study evaluates the response comparability between 361 elderly hip fracture patients admitted from the community to seven Baltimore area hospitals between 1984 and 1986 and interviewer selected proxies on items pertaining to patients' pre-fracture health and functional status. Agreement across items ranges from very poor to good and varies with respect to the health or functional area assessed. Proxies tend to overestimate patient disability relative to the patients themselves, especially with regard to capacity to perform instrumental activities of daily living. Although proxies who report the greatest contact with patients respond most comparably to the patients, when they do disagree, proxies with the greatest patient contact tend to overestimate patient disability. The authors suggest that attention to item construction and phrasing may improve response comparability. 相似文献
62.
Health-related quality of life assessed before and during chemotherapy predicts for survival in multiple myeloma 总被引:5,自引:0,他引:5
Measurement of health-related quality of life was integrated into a randomized trial (NMSG 4/90) comparing melphalan/prednisone to melphalan/prednisone + interferon α-2b in newly diagnosed multiple myeloma. One of the aims of the study was to assess the prognostic significance of quality-of-life scores, using the EORTC QLQ-C30 questionnaire. Univariate analysis showed a highly significant association with survival from the start of therapy for physical functioning as well as role and cognitive functioning, global quality of life, fatigue and pain. In multivariate analysis, physical functioning and W.H.O. performance status were independent prognostic factors ( P values=0.001 for both) when analysed in a Cox regression model with the somatic variables β-2 microglobulin, skeletal disease and age. The best prediction for survival from the start of therapy was obtained by combining the β-2 microglobulin and physical functioning scores in a variable consisting of three risk factor levels with an estimated median survival of 17, 29 and 49 months, respectively. At a 12 months landmark analysis, the relative risk for patients with physical functioning score 0–20 v 80–100 was 5.63 (99% CI 2.76–11.49), whereas the relative risk for patients without an objective response to chemotherapy compared to those with at least a minor response was 2.32 (99% CI 1.44–3.74). Quality-of-life assessment may be an independent and valuable addition to the known prognostic factors in multiple myeloma. 相似文献
63.
Rosemary Cant 《Australian Occupational Therapy Journal》1993,40(3):113-121
Newer policies of community care for those with disabilities have resulted in the home becoming the usual site of care. Policy makers must now give attention to the needs of those at home giving this care. This article explores the constraints on sociability opportunities of 73 mothers who were caring for children with disabilities. These opportunities are often built into leisure pursuits for women without caring responsibilities. However, choice of out-of-house leisure activity was circumscribed for the mothers in this study and their reported leisure activities revolved around home and neighbourhood. Even these sites offered limited scope for sociability because of the way in which caring affected domestic space and because of the characteristics of the modern Australian suburb. It is argued in this paper that personal time and personal domestic space are needed by care-givers so their sociability needs can be fulfilled. An understanding of the constraints imposed by use of the home as a place of care may make possible the planning of a rearrangement of domestic space to increase sociability opportunities for carers. 相似文献
64.
心理因素对小学生脑力工作能力影响的研究 总被引:4,自引:2,他引:2
采用横断面研究方法,对180名小学三年级学生脑力工作能力与其智力、性格、学习动机等心理因素和学习、睡眠时间等作息因素的关系进行分析研究。验证了学习、睡眠时间是影响学生脑力工作能力重要的外部因素;脑力工作能力与智力和学习成绩呈正相关。学生自身的心理因素中,学习动机对脑力工作能力有重要影响,所以激发和强化学生的学习动机,是保持和提高学生学习工作能力的有效手段;而性格内外向性、情绪稳定性等因素,对脑力工作能力的影响不明显。 相似文献
65.
Kevin L. Greason M.D. Jose A. Acosta M.D. Thomas J. Magrino M.D. Moogil Choe M.D. 《Diseases of the colon and rectum》1996,39(6):702-704
PURPOSE: This study was undertaken to clarify the importance of bleeding vascular ectasia of the colon as the etiology of massive lower gastrointestinal hemorrhage in patients 40 years of age or younger. METHODS: An otherwise healthy 21-year-old male was admitted to a tertiary medical center with massive lower gastrointestinal hemorrhage. Technetium-labeled red blood cell scan, selective visceral angiography, and colonoscopy identified the source of bleeding as vascular abnormality of the descending colon. Segmental colonic resection was performed. RESULTS: Histologic review of the specimen demonstrated a vascular ectasia. The patient recovered uneventfully and has had no further stigmata of hemorrhage. A review of the literature was undertaken to make clear the significance of vascular ectasia as the source for massive colonic hemorrhage in the young adult. CONCLUSION: This is the first report that documents histologically a vascular ectasia as the source of massive lower gastrointestinal hemorrhage in an otherwise healthy patient less than 40 years of age. Vascular ectasia is an uncommon cause of lower gastrointestinal hemorrhage in the young adult.The Chief, Bureau of Medicine and Surgery, Navy Department, Washington, DC, Clinical Investigation Program sponsored this report #84-16-1968-532, as required by HSETCINST 6000.41A. The views expressed in this article are those of the authors and do not reflect the official policy or position of the Department of the Navy, Department of Defense, or the United States Government. 相似文献
66.
67.
68.
69.
医药行业科技成果产业化与其他行业科技成果转化相比具有更高的风险,转化能力也是最低的,因此,对其从事前、事中、事后三方面加强风险控制具有重要的观实意义。 相似文献
70.
Galanin-like immunoreactivity has been visualized in nerve fibers in the islets of Langerhans, suggesting an involvement of
galanin in the neural regulation of islet function. In this study, we investigated the effects of galanin on basal and stimulated
insulin and glucagon secretion by infusing the peptide at three different dose rates in rats. We also studied the direct effect
of galanin on insulin secretion from freshly isolated rat islets. At 320 pmol/kg/min, but not at 20 or 80 pmol/kg/min, galanin
lowered basal plasma insulin levels. In contrast, basal plasma glucagon levels were lowered by galanin already at 20 and 80
pmol/kg/min. Furthermore, galanin inhibited both glucose- and arginine-induced insulin release at all three dose levels, whereas
arginine-induced glucagon release was not affected by galanin. Glucose-stimulated insulin secretion from isolated rat islets
was dose-dependently suppressed by galanin (10-6-10-8M). Therefore, it is concluded that galanin in rats inhibits insulin secretion, both in vivo and in vitro, and that at lower
dose levels, the peptide also inhibits basal glucagon release. 相似文献