首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   523篇
  免费   65篇
  国内免费   5篇
耳鼻咽喉   1篇
儿科学   2篇
基础医学   6篇
口腔科学   2篇
临床医学   7篇
内科学   2篇
皮肤病学   45篇
神经病学   1篇
特种医学   11篇
外科学   33篇
综合类   57篇
预防医学   5篇
眼科学   364篇
药学   32篇
中国医学   25篇
  2024年   2篇
  2023年   19篇
  2022年   19篇
  2021年   38篇
  2020年   36篇
  2019年   20篇
  2018年   24篇
  2017年   21篇
  2016年   19篇
  2015年   24篇
  2014年   31篇
  2013年   44篇
  2012年   40篇
  2011年   28篇
  2010年   30篇
  2009年   28篇
  2008年   24篇
  2007年   18篇
  2006年   19篇
  2005年   17篇
  2004年   8篇
  2003年   7篇
  2002年   6篇
  2001年   8篇
  2000年   2篇
  1999年   5篇
  1998年   5篇
  1997年   2篇
  1996年   2篇
  1995年   2篇
  1994年   2篇
  1993年   2篇
  1992年   1篇
  1991年   2篇
  1990年   1篇
  1988年   2篇
  1987年   1篇
  1985年   1篇
  1984年   2篇
  1983年   1篇
  1982年   5篇
  1981年   5篇
  1980年   5篇
  1979年   2篇
  1978年   7篇
  1977年   1篇
  1976年   2篇
  1975年   3篇
排序方式: 共有593条查询结果,搜索用时 31 毫秒
71.
AIM: To report a simple approach to actively remove high viscosity silicone oil through a 23-gauge cannula via pars plana. METHODS: Forty-eight eyes of 48 patients underwent silicone oil (5700 centistokes) removal (SOR) were enrolled. A section of blood transfusion set was prepared to connect a standard 23-gauge cannula and vitrectomy machine. Silicone oil was removed with suction of 500-mm Hg vacuum through the cannula. Main outcome measures were SOR duration, number of sutured sites, intraocular pressure (IOP), best-corrected visual acuity (BCVA), and complications. RESULTS: Silicone oil was successfully removed in all cases. The mean SOR time was 5.70±0.85min. Nine eyes (18.75%) needed suture partial sclerotomies. No intraoperative complications were noted. Transient hypotony (≤8 mm Hg) was seen in 3 eyes (6.25%) on postoperative day 1, but all resolved within 1wk. Retinal reattachment was achieved in all cases and no other postoperative complications were noted during 3-month following-up. BCVA at the final visit improved or stabilized in all patients comparing to the preoperative level. CONCLUSION: Active removal of high viscosity silicone oil through a 23-gauge instrument cannula jointed with blood transfusion set is a practical and reliable technique when considering two sides of efficacy and safety.  相似文献   
72.
Purpose:The purpose of this study is to evaluate the anatomical and functional outcomes of 25-gauge (G) pars plana vitrectomy (PPV) in patients with cytomegalovirus retinitis (CMVR)-related rhegmatogenous retinal detachment (RRD).Methods:Single-center retrospective consecutive case series of patients who underwent 25-G PPV for CMVR-related RRD repair with a minimum follow-up of 3 months. Complete anatomic success was defined as the complete attachment of retina including the periphery. Best-corrected visual acuity (BCVA) of ≥20/400 was defined as functional success.Results:Sixteen eyes of 15 patients were included in the study. Eleven patients were human immunodeficiency virus positive, three patients had hematological malignancies, and one patient suffered from dyskeratosis congenita. The mean follow-up was 20.5 ± 17.4 months (range 3–60 months). Complete anatomical success was seen in 15 eyes (93.75%). One eye had a residual inferior detachment with attached macula. Silicone oil was used as tamponade in 15 eyes and C3F8 gas in one eye. The mean change in BCVA was statistically significant, preoperative LogMAR BCVA was 2.05 ± 0.94 while the final follow-up postoperative LogMAR BCVA was 1.03 ± 0.61 (P < 0.001). Thirteen eyes (81.25%) had final BCVA ≥20/400.Conclusion:Microincision vitrectomy surgery can achieve excellent retinal reattachment rates in post-CMVR RRDs without significant intraoperative and postoperative complications. The visual outcome varies depending on the status of the optic disc and macula. Majority of the patients maintained functional vision.  相似文献   
73.
74.
75.
76.
ABSTRACT

Despite recent advances in the medical management of diabetic retinal disease, there remain established indications for vitreoretinal surgery in the treatment of severe proliferative diabetic retinopathy. These include non-clearing vitreous hemorrhage and tractional retinal detachment. Advances in surgical instrumentation, technique, and experience have led to improved visual outcomes, as well as a corresponding decrease in the incidence of postoperative complications. However, the presence of systemic and ocular factors in diabetic patients increases the risk of adverse events compared to non-diabetic individuals. This review will focus on the most important postoperative complications following pars plana vitrectomy, with specific considerations for the diabetic patient.  相似文献   
77.
Purpose: To describe the characteristics, management, and outcomes of open globe injured (OGI) eyes that underwent pars plana vitrectomy (PPV) for posterior segment complications. Methods: Retrospective chart review of cases that underwent PPV for posterior segment complications associated with OGI between 2003-2012 at University Hospital, Newark, NJ. Results: 120 eyes were identified and classified as follows: “early retinal detachment (RD)” (within 30 days of OGI), 64 (53%) eyes; “delayed RD” (≥30 days after OGI), 30 (25%) eyes; and “no RD,” 26 (22%) eyes. Injuries included penetrating (39 (33%) eyes), rupture (60 (50%) eyes), and penetrating wounds with retained intraocular foreign body (21 (17%) eyes). Injuries in Zones I, II, and III were seen in 40 (35%) eyes), 38 (34%) eyes, and 35 (31%) eyes, respectively, with statistically different ocular trauma scores (p<0.01) associated with each zone of injury. Mean presenting and final logMAR VA were 2.20± 0.63 and 1.87 ±0.60, respectively (p<0.01), with a mean follow-up of 3.2 years. Final overall anatomic success after surgeries was 98% for early RD and 95% for delayed RD. Conclusion: Despite a high anatomic success rate, the overall functional success rate for eyes with posterior segment trauma that undergo PPV is poor and comparable to other studies.  相似文献   
78.
Carbon dioxide (CO2) laser treatment is a common therapeutic modality for many dermatologic conditions. It uses a high energy, infrared beam of light, which selectively targets water-containing tissue resulting in controlled ablative resurfacing. This modality, however, can manifest significant cosmetic side effects. Here we report a case of verruca plana manifesting as a response to CO2 laser treatment. A 74-year-old female with recent Mohs surgery for a basal cell carcinoma, presented for full-face-fractionated CO2 treatment to address her surgical scars in addition to treating her mild diffuse actinic damage. Six weeks post treatment, the patient developed erythematous thin plaques over the areas that had been treated. Histology was consistent with verruca plana. Lesions showed mild improvement with topical tretinoin. Verruca plana are benign and typically self-limited; however, they can present a significant cosmetic burden to patients and are an important complication to consider when performing elective cosmetic procedures.  相似文献   
79.
针灸疗法具有适应证广、简便经济、疗效显著等特点,且具有较好的安全性,无毒副作用,为其他药物疗法所不及,值得临床广泛应用。  相似文献   
80.
目的:观察艾拉光动力疗法(5-盐酸氨酮戊酸光动力疗法,5-aminolevulinie acid photodynamic therapy,ALA-PDT)治疗尖锐湿疣(Condyloma acuminatum,CA)及多发性跖疣(Verruca phmtaris,PS)的安全性与疗效.方法:以ALA-PDT治疗151例CA及PS患者,末次治疗后第1周进行疗效评价,第4、8周和12周观察复发率和不良反应.结果:疗程结束后CA及PS的疣体清除率分别为96.5%和75.4%,治疗后复发率分别为12.1%和16.3%.未发生系统不良反应,局部不良反应发生率分别为10.47%和3.08%,主要为烧灼感,局部红肿.结论:ALA-PDT治疗CA及PS治愈率均较高,但治疗CA疗效更好.复发率低,安全性好.  相似文献   
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号