全文获取类型
收费全文 | 46896篇 |
免费 | 2985篇 |
国内免费 | 1454篇 |
专业分类
耳鼻咽喉 | 648篇 |
儿科学 | 1210篇 |
妇产科学 | 716篇 |
基础医学 | 4763篇 |
口腔科学 | 742篇 |
临床医学 | 4770篇 |
内科学 | 6660篇 |
皮肤病学 | 1886篇 |
神经病学 | 3086篇 |
特种医学 | 1099篇 |
外国民族医学 | 1篇 |
外科学 | 2380篇 |
综合类 | 6613篇 |
现状与发展 | 3篇 |
预防医学 | 4977篇 |
眼科学 | 501篇 |
药学 | 7179篇 |
29篇 | |
中国医学 | 2382篇 |
肿瘤学 | 1690篇 |
出版年
2024年 | 57篇 |
2023年 | 492篇 |
2022年 | 996篇 |
2021年 | 1635篇 |
2020年 | 1402篇 |
2019年 | 1278篇 |
2018年 | 1353篇 |
2017年 | 1385篇 |
2016年 | 1399篇 |
2015年 | 1486篇 |
2014年 | 2767篇 |
2013年 | 3216篇 |
2012年 | 2825篇 |
2011年 | 2965篇 |
2010年 | 2407篇 |
2009年 | 2244篇 |
2008年 | 2347篇 |
2007年 | 2369篇 |
2006年 | 1991篇 |
2005年 | 1870篇 |
2004年 | 1535篇 |
2003年 | 1378篇 |
2002年 | 1104篇 |
2001年 | 1021篇 |
2000年 | 876篇 |
1999年 | 840篇 |
1998年 | 698篇 |
1997年 | 679篇 |
1996年 | 613篇 |
1995年 | 624篇 |
1994年 | 567篇 |
1993年 | 441篇 |
1992年 | 479篇 |
1991年 | 434篇 |
1990年 | 383篇 |
1989年 | 372篇 |
1988年 | 354篇 |
1987年 | 321篇 |
1986年 | 266篇 |
1985年 | 310篇 |
1984年 | 247篇 |
1983年 | 184篇 |
1982年 | 211篇 |
1981年 | 170篇 |
1980年 | 142篇 |
1979年 | 110篇 |
1978年 | 103篇 |
1977年 | 83篇 |
1976年 | 68篇 |
1975年 | 54篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
91.
92.
中美中学生对由父母原因引起的考试焦虑认知研究 总被引:1,自引:0,他引:1
目的:比较中国和美国的中学生对由父母原因引起的考试焦虑的认知情况。方法:采用“失败结果预期(FOE)”问卷中的由父母原因引起的考试焦虑12项,测量中美两国公立学校14、15岁的1215名中学生对考试焦虑原因的认知。结果:1.相似认知:两国学生在由父母原因引起的考试焦虑方面有类似的认知,包括父母会担心自己能否进入高一级学校、会让父母烦恼等。2.跨文化的差异:表现为中国学生更多是因为父母责备、辜负了父母期望或会让父母生气而导致考试焦虑;而美国学生更多是由于父母认为他们不能面对生活中的挑战而产生焦虑。3.性别差异:表现在美国的女中学生在7个项目上、中国的男中学生在2个项目上分别比本国异性有更大程度的焦虑(P〈0.05)。结论:中美中学生对由父母原因引起的考试焦虑方面有类似的认知,但存在文化差异和性别差异。 相似文献
93.
94.
S. M. Fuchs C. Heinemann S. Schliemann-Willers H. Härtl J. W. Fluhr P. Elsner 《Skin research and technology》2006,12(4):223-227
OBJECTIVE: In the present study, we evaluated the anti-inflammatory activity of Poria cocos (PoCo) on experimentally induced irritant contact dermatitis (ICD) in a repeated sodium lauryl sulphate (SLS) irritation model. METHODS: The anti-irritative effect of PoCo was evaluated with a visual score and quantified by non-invasive bioengineering methods, namely chromametry and transepidermal water loss. Three concentrations of PoCo in base cream DAC (amphiphilic emollient; German pharmacopoeia) were tested in a 4-day repetitive irritation test using SLS. RESULTS: A statistically significant anti-inflammatory activity was observed for PoCo by all three methods when applied in parallel to the induction period of ICD. Application of PoCo after induction of ICD once a day for 5 days, starting just at the end of 4 days, was without any effect. CONCLUSION: An anti-inflammatory efficacy of PoCo on the elicitation phase of the ICD induced by repeated SLS test could be observed and quantified by three independent, non-invasive biophysical assessment parameters. This effect can be explained by its influence on pro-inflammatory enzymes, namely phospholipase A2. 相似文献
95.
AIMS: Diabetic ketoacidosis (DKA), a life-threatening acute complication of Type 1 diabetes, may be preventable with frequent monitoring of glycaemia and ketosis along with timely supplemental insulin. This prospective, two-centre study assessed sick day management using blood 3-hydroxybutyrate (3-OHB) monitoring compared with traditional urine ketone testing, aimed at averting emergency assessment and hospitalization. METHODS: One hundred and twenty-three children, adolescents and young adults, aged 3-22 years, and their families received sick day education. Participants were randomized to receive either a blood glucose monitor that also measures blood 3-OHB (blood ketone group, n = 62) or a monitor plus urine ketone strips (urine ketone group, n = 61). All were encouraged to check glucose levels > or = 3 times daily and to check ketones during acute illness or stress, when glucose levels were consistently elevated (> or = 13.9 mmol/l on two consecutive readings), or when symptoms of DKA were present. Frequency of sick days, hyperglycaemia, ketosis, and hospitalization/emergency assessment were ascertained prospectively for 6 months. RESULTS: There were 578 sick days during 21,548 days of follow-up. Participants in the blood ketone group checked ketones significantly more during sick days (276 of 304 episodes, 90.8%) than participants in the urine ketone group (168 of 274 episodes, 61.3%) (P < 0.001). The incidence of hospitalization/emergency assessment was significantly lower in the blood ketone group (38/100 patient-years) compared with the urine ketone group (75/100 patient-years) (P = 0.05). CONCLUSIONS: Blood ketone monitoring during sick days appears acceptable to and preferred by young people with Type 1 diabetes. Routine implementation of blood 3-OHB monitoring for the management of sick days and impending DKA can potentially reduce hospitalization/emergency assessment compared with urine ketone testing and offers potential cost savings. 相似文献
96.
Tomoko FUKUNAGA Satoshi UKAI Toshiko KOBAYASHI Tsuyoshi NISHIMURA Masatoshi TAKEDA 《Psychogeriatrics》2006,6(4):159-167
Background: Progression of the core and accessory symptoms of dementia can be slowed if drug therapies and psychosocial interventions are administered at an early stage. The aim of this study was to develop and standardize a neuropsychological test for the elderly that can detect dementia at an early stage with high sensitivity and can evaluate a wide range of severities of dementia based on assessments of various cognitive functions. Methods: A preliminary test consisting of 23 items and the Nishimura Mental State Scale for the Elderly (NM Scale), which evaluates the mental functions of elderly individuals by observing their actual behaviors in daily life, were administered to 448 elderly subjects. After applying Hayashi’s quantification theory type I to the results, we revised the preliminary test to construct a neuropsychological test for the elderly, which we named the Nishimura Dementia Test (ND Test), and standardized it. Then, we examined its validity and test–retest reliability. Results: Among the 448 subjects, there was a strong correlation between the ND Test scores and NM Scale scores. The ND Test showed a good general agreement rate for the discrimination of the severity of dementia, and good sensitivity and specificity of discrimination of dementia when compared with the actual NM Scale. Using different groups of elderly subjects, the ND Test showed validity and test–retest reliability, and the ND Test scores showed strong correlations with the Revised Hasegawa Dementia Scale scores and the Mini‐Mental State Examination scores. Conclusions: The ND Test is based on assessment of a variety of cognitive functions and can evaluate a wide range of severities of dementia with good validity and reliability. 相似文献
97.
直肠Ca男性患者手术病人麻醉后插尿管的临床观察 总被引:1,自引:0,他引:1
目的观察直肠Ca男性患者手术麻醉后插尿管对患者的好处。方法对92例直肠Ca手术男性患者随机分成实验组及对照组进行麻醉后插尿管及常规术前1小时插尿管做法对比。结果直肠Ca手术男性患者选择麻醉后插尿管更优于术前1小时常规插尿管,成功率更高。结论直肠Ca男性患者手术采用麻醉后插尿管值得推广采用。 相似文献
98.
目的:通过对HIV抗体快速检测试剂的临床评估,为HIV检测试剂的临床应用提供参考.方法:对快速试剂的使用性能进行比较,并采用美国输血协会(AABB)血清盘、临床样品血清盘、特性血清盘(阳性样品盘)、稀释系列血清盘评估快速试剂的敏感性和特异性.结果:三种快速试剂在检测AABB血清盘时,敏感性分别是86.4%、86.4%、100%,特异性皆为100%;三种快速试剂在检测临床样品血清盘时,敏感性分别是88.6%、91.4%、97.1%,特异性皆为100%.快速试剂具有很高的阳性预期值,对于低危人群(感染率很低人群)也具有很高的阴性预期值.快速试剂检测弱阳性的样品(酶联试剂s/co比值小于6~8的样品)存在漏检.快速试剂与ELISA参考试剂在分析灵敏度方面相差3个以上倍比稀释度.结论:快速试剂具有较好的使用特性,非常适用于样本量较少的实验室及对低危人群的HIV筛查,在对高危人群筛查时,可能有弱阳性样品漏检,同时快速试剂在分析灵敏度方面有待提高. 相似文献
99.
目的:分析儿童呼吸道苛养菌的感染率及常用抗生素的耐药状况。方法:采用儿童呼吸道2050份咽拭子及痰标本进行苛养菌分离培养与鉴定,并对其中617株苛养菌做了药敏试验,结果:显示275株肺炎链球菌,耐药率较高的有红霉素81.1%,苯唑西林76.9%,复方磺胺甲恶唑76.9%,四环素65.4%;104株流感嗜血杆菌、184株副流感嗜血杆菌、54株卡他莫拉菌对氨苄西林耐药率分别为17.6%,28.9%,64.9%,对亚胺培南/西司他丁耐药率分别为16.4%,16.5%,0,同时复方磺胺甲恶唑的耐药率也分别高达56.7%,56.7%,64.9%。结论:提示苛养菌在儿童呼吸道感染中占有重要的地位,及时掌握这类细菌的耐药动态,对合理使用抗生素,延缓耐药株的产生有极其重要的临床意义。 相似文献
100.
21 d-6°头低位卧床期间运动训练对动态姿态平衡的影响 总被引:1,自引:0,他引:1
目的探讨21 d-6°头低位卧床和卧床运动训练对动态姿态平衡和控制功能的影响. 方法 10名健康男性青年被试者分为卧床对照组和卧床训练组,每组5人,卧床期间训练组每天进行2次、每次30 min逐级增加负荷的头低位功率自行车训练;分别于卧床前和卧床后21 d进行了动态姿态平衡和双膝等速肌力的测试. 结果与卧床前相比,对照组动态本体感觉得分和运动控制适应能力明显降低,双膝相对峰力矩明显降低,同时伴有腘绳肌与股四头肌峰力矩屈/伸比值的明显增加;训练组动态本体感觉得分和运动控制适应能力明显高于对照组,而腘绳肌与股四头肌峰力矩屈/伸比值无明显改变. 结论 21 d-6°头低位卧床运动训练能够明显改善卧床后动态姿态平衡及其动态运动适应功能. 相似文献