A diagnostic profile of gerstmann's syndrome: a case study

The authors present a diagnostic profile of Gerstmann's syndrome, the subject being a girl, aged 10 years 3 months, right‐handed, and at the time of this study in her fourth school year (Grade 4). The subject's verbal and non‐verbal IQ scores and additional assessment data were analyzed and summative responses given. The Senior South African Individual Scale – Revised was administered to determine the intellectual functioning of the subject. A qualitative analysis of the results revealed average intellectual functioning on both the verbal and full scales. The non‐verbal scale revealed low average intellectual functioning. The difference between the verbal scale IQ and the non‐verbal scale IQ was statistically significant at the 5% level of reliability. Based on the scatter analysis it is evident that the subject experienced difficulties with regards to numerical reasoning, handwriting, spatial disorientation and difficulty in mental manipulation of images, as associated with Gerstmann's syndrome.     

家兔右室流出道细胞双孔钾通道电流特性的分析研究

目的已知特发性室速主要起源于右室流出道(RVOT),由于技术上的困难,目前对特发性右室流出道室速(RVOT-VT)的离子通道机制研究很少,本实验意在探索右室心室肌(RV)和RVOT的双孔钾通道电流(IK2p)的特性及其在RVOT-VT发生机制中可能参与的作用。方法采用全细胞膜片钳技术记录右室和右室流出道心肌细胞的单细胞电流。结果 RVOT的稳态外向电流较右室的小。对稳态电流进一步研究发现,右室流出道和右室心肌细胞上均存在IK2p。右室流出道细胞的IK2p电流密度明显小于右室细胞。结论首次在电生理水平上,证实了家兔右室心肌细胞上存在IK2p,RVOT心肌细胞的IK2p电流密度小于RV心肌细胞,是构成右室流出道APD离散度增大及外向电流降低的基础,从而易出现EAD,进而促进RVOT-VT的发生。     

Theory of mind impairment in right hemisphere damage: A review of the evidence

Among the hypothesized causes of communication impairments in people with damage to the right cerebral hemisphere (RHD) is an underlying impairment in Theory of Mind (ToM) (the ability to make inferences about other peoples' mental states). In this review, evidence is considered for a ToM impairment in adults with RHD by approaching the issue from two directions. First, indirect evidence for impairment of ToM is reviewed by looking at studies on the effects of RHD on the comprehension of indirect requests, that is, requests in which the speaker's wishes are not explicitly stated but must be inferred by the listener. Second, studies that directly investigate the effects of RHD on performance on tasks intended to tap ToM are reviewed. On the basis of the papers reviewed here, it is concluded that although people with RHD do show impairments on a variety of tasks that are thought to involve ToM cognition, evidence for a specific ToM impairment is still inconclusive. It is recommended that future studies take care to distinguish individual differences in participants' linguistic production and lesion location, that more care is taken to control for task difficulty, and that well-controlled studies are combined with more naturalistic, ecologically valid tasks.     

Primary reperfusion in acute right ventricular infarction: An observational study简

AIM: To investigate the impact of primary reperfusion therapy (RT) on early and late mortality in acute right ventricular infarction (RVI).METHODS: RVI patients (n = 679) were prospectively classified as without right ventricular failure (RVF) (class A, n = 425, 64%), with RVF (class B, n = 158, 24%) or with cardiogenic shock (CS) (class C, n = 96, 12%). Of the 679 patients, 148 (21.7%) were considered to be eligible for thrombolytic therapy (TT) and 351 (51.6%) for primary percutaneous coronary intervention (PPCI). TIMI 3-flow by TT was achieved for A, B and C RVI class in 65%, 64% and 0%, respectively and with PPCI in 93%, 91% and 87%, respectively.RESULTS: For class A without RT, the mortality rate was 7.9%, with TT was reduced to 4.4% (P < 0.01) and with PPCI to 3.2% (P < 0.01). Considering TT vs PPCI, PPCI was superior (P < 0.05). For class B without RT the mortality was 27%, decreased to 13% with TT (P < 0.01) and to 8.3% with PPCI (P < 0.01). In a TT and PPCI comparison, PPCI was superior (P < 0.01). For class C without RT the in-hospital mortality was 80%, with TT was 100% and with PPCI, the rate decreased to 44% (P < 0.01). At 8 years, the mortality rate without RT for class A was 32%, for class B was 48% and for class C was 85%. When PPCI was successful, the long-term mortality was lower than previously reported for the 3 RVI classes (A: 21%, B: 38%, C: 70%; P < 0.001).CONCLUSION: PPCI is superior to TT and reduces short/long-term mortality for all RVI categories. RVI CS patients should be encouraged to undergo PPCI at a specialized center.     

Acute Heart Failure after Percutaneous Pulmonary Valve (Melody Valve) Implantation

We present a case of a 38‐year‐old male who developed acute heart failure early after percutaneous pulmonary valve implantation with the Melody valve (Medtronic, Minneapolis, MN, USA).     

房颤患者长间歇与心功能的相关性分析

目的探讨心房颤动患者长间歇与心功能的相关性。方法选取我院2012年3月~2017年6月房颤患者127例,分别记录患者的年龄、性别、超声心动图指标(LAD、LVEDD、LVSDD、IVS、LVPW、EF)及动态心电图中是否伴有长间歇及长间歇次数。根据患者是否伴有长间歇分为房颤伴长间歇组与房颤不伴长间歇组。结果房颤伴长间歇组与房颤不伴长间歇组比较,LAD显著增大(P0.05);两组间LVEDD、LVSDD、IVS、LVPW、EF比较,差异无统计学意义;相关分析示长间歇次数与LAD大小呈正相关(P0.05),与LVEDD、LVSDD、IVS、LVPW、EF之间无相关性。结论房颤伴长间歇会导致患者左房增大,可间接导致心功能的恶化,且随长间歇次数的增加而增加。