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Objective: The scientific quality of research is an important ethical issue. To clarify the quality of research projects in pharmacotherapy/pharmacology,
40 randomly selected research projects in pharmacotherapy/pharmacology submitted to a research ethics committee were reviewed.
Results: Eight of the projects would not have contributed new knowledge nor were they necessary as controls for the results of previous
research. Fifteen of the research protocols were of good quality, 15 could be used after revisions, and 10 were unfit for
use. Eleven of the research projects were not finished 5 years after they were started. A written report was produced from
26 of the projects. Nine were of good quality and could be accepted for publication in a medical journal, 10 of the reports
were in need of revision before publication, and 7 should not be accepted for publication.
Conclusion: Research in this field ought to be improved, and ways to improve the standard of clinical trials in pharmacotherapy are
dicussed.
Received: 1 April 1996 / Accepted in revised form: 28 June 1996 相似文献
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Critical care nurses, ethical decision-making and stress 总被引:2,自引:0,他引:2
Considerable attention has focused on describing ethical issues that critical care nurses face in their practice; however, less attention has been directed at describing the process of ethical decision-making. Systematic research linking aspects of ethical-decision making and stress is lacking. This cross-sectional study examines the relationship between selected aspects of ethical decision-making, stress and selected nurse characteristics. Sixty-one critical care nurses completed the Nurse's Ethical Decision Making—ICU Questionnaire and the Health Professions Stress Inventory. Findings revealed that nurses who selected the patient advocacy model had significantly higher nurse autonomy scores, that perceived anxiety had a negative association with nurse autonomy, and that workplace restrictions and stress were related. 相似文献
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Eric M Cheng Andrew Siderowf Kari Swarztrauber Mahmood Eisa Martin Lee Barbara G Vickrey 《Movement disorders》2004,19(2):136-150
Parkinson's disease (PD) is a major cause of disability. To date, there have been no large-scale efforts to measure the quality of PD care because of a lack of quality indicators for conducting an explicit review of PD care processes. We present a set of quality indicators for PD care. Based on a structured review of the medical literature, 79 potential indicators were drafted. Through a two-round modified Delphi process, an expert panel of seven movement disorders specialists rated each indicator on criteria of validity, feasibility, impact on outcomes, room for improvement, and overall utility. Seventy-one quality indicators met validity and feasibility thresholds. Applying thresholds for impact on outcomes, room for improvement, and overall utility, a subset of 29 indicators was identified, spanning dopaminergic therapy, assessment of functional status, assessment and treatment of depression, coordination of care, and medication use. Multivariable analysis showed that overall utility ratings were driven by validity and impact on outcomes (P < 0.01). An expert panel can reach consensus on a set of highly rated quality indicators for PD care, which can be used to assess quality of PD care and guide the design of quality improvement projects. 相似文献
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男科学的科研思路及选题 总被引:1,自引:1,他引:0
男科疾病诊治水平的不断提高离不开科研的发展。笔者根据自己多年在男科领域的科研工作经历,认为男科的科研选题对提高男科疾病的诊治水平意义重大。男科领域科研选题应密切结合男科临床需要,遵循重要性、创新性、科学性、可行性及现实性等原则,面向常见男科疾病的基础、治疗和流行病学方向选题。选题要注重方法。 相似文献