等离子刀与机械刨削在治疗膝关节类风湿性关节炎中的作用分析

目的:比较等离子刀与刨削系统在治疗膝关节类风湿性关节炎中的作用.方法:采用随机对照前瞻性研究,等离子刀治疗组21例,机械刨削对照组17例,全部病例获得6～39个月(平均19.5个月)的随访.随访结果采用Lvsholm膝关节功能评分.结果:对美国风湿病学会RA分期处于Ⅰ期和Ⅱ期的病例,等离子刀治疗组的膝关节功能评分优于对照组(P＜0.05);而对于Ⅲ期的病例,等离子刀治疗组与对照组差异无统计学意义(P＞0.05).结论:等离子刀技术对RA分期处于Ⅰ期和Ⅱ期的病例是首选治疗方法.     

RADIOFREQUENCY ABLATION USING HYPERTONIC SALINE SOLUTION INSTILLATION： AN EX VIVO STUDY

Objective To determine whether radiofrequency ablation using hypertonic saline solution instillation can increase the extent of thermally mediated coagulation in ex vivo pig liver tissue. Methods Fifty-six radiofrequency ablation lesions were produced in fresh ex vivo pig＇s liver. According to different saline solutions, the lesions were divided into six groups： 25% acetic acid, 18% NaCl, 10% NaCl, 5% NaCl, 0.9% NaCl, and distilled water. After radiofrequency ablation, the lesions size and morphology were measured and compared.Results Using different instillation, the volume of coagulation necrosis was different： 25% acetic acid 〉18% NaCl 〉10% NaCl 〉5% NaCl 〉0.9% NaCl〉distilled water. Conclusion Radiofrequency ablation using hypertonic saline solution instillation can increase the volume of radiofrequency ablation induced necrosis.     

射频消融迷宫手术联合应用可达龙治疗风心病房颤的对比研究

目的对比研究射频消融迷宫手术联合应用可达龙治疗风心病房颤的窦性心律转复率及其影响因素。方法射频消融迷宫手术组病人在瓣膜手术时行射频消融迷宫手术，术中术后应用可达龙；对照组在瓣膜手术时不行射频消融迷宫手术，但同样应用可达龙，观察两组病人的窦性心律转复率，并分析其影响因素。结果射频消融迷宫手术组窦性心律转复率为77．5％，对照组为6．1％，两组间有明显差异（P〈0．01）。术前病人左房内径小、房颤时间短者有利于窦性心律的转复，而术前射血分数、肺动脉收缩压、心功能分级、心胸比对其无明显影响；射频消融迷宫手术后，即使没有恢复窦性心律的病人其室性心率也比术前明显降低。结论射频消融迷宫手术对治疗风心病房颤效果令人满意，对左房内径小、房颤时间短者效果更好。     

膝关节骨关节炎治疗的研究进展

骨关节炎（osteoarthritis,OA）是一种以关节软骨退行性改变和继发性骨增生为特征的慢性关节疾病,其中以膝关节骨关节炎（knee osteoarthritis,KOA）最为常见。目前针对KOA的非手术治疗仅能达到缓解疼痛、改善功能的目的。积极的手术治疗效果虽好,但假体定位困难,手术难度高,因此急需新的治疗方式以改善患者预后。基于KOA的最新临床研究,本文对膝神经射频消融术、机器人辅助膝关节置换术、生物治疗和激光治疗等4种新的治疗方式开展评述。     

射频消融在脾脏疾病中的应用现状

射频消融（radiofrequency ablation,RFA）是一种良好的消融、凝血工具,较早应用于肝外科疾病手术,其作用已经从单纯消融肝脏肿瘤扩展到无血肝切除。然而RFA在脾脏疾病中应用相对局限,其临床价值似乎被低估。本文总结RFA在脾脏各种疾病中的应用,以期为临床拓展思路,为RFA在脾脏疾病的应用提供参考。     

Radiofrequency irradiation attenuates angiogenesis and inflammation in UVB-induced rosacea in mouse skin

Rosacea is a skin inflammatory condition accompanied by cutaneous signs such as oedema, flushing, erythema, telangiectasia and pustules. Generally, rosacea is triggered by ultraviolet B (UVB) exposure. When exposed to UVB, skin epidermis thickens and produces elevated levels of pro-inflammatory cytokines, especially keratinocyte-related VEGF, a potent angiogenic factor. The upregulations of VEGF expression and its secretion promote the formation of new blood vessels and exacerbates rosacea. In this study, radiofrequency (RF) irradiation reduced keratinocyte proliferation in the epidermal layer, the expressions of pro-inflammatory cytokines, angiogenesis-related inflammatory factors and VEGF in our UVB-induced model of rosacea in vitro and in vivo. RF irradiation attenuated VEGF-induced angiogenesis-associated processes such as tube formation, cell migration and endothelial cell proliferation. Notably, blood vessel densities in the skins of UVB-treated mice and rosacea patients were significantly decreased by RF irradiation. These results provide experimental and molecular evidence regarding the effectiveness of RF irradiation for the treatment of rosacea.     

Treatment of lentigo maligna with combination laser therapy: recurrence at 8 months after initial resolution

This is a case report of an 89‐year‐old woman with a lentigo maligna treated with alexandrite and ruby lasers. The lentigo maligna never completely resolved despite multiple treatments. Marked cosmetic improvement, however, was obtained. No adverse sequelae have occurred.     

Intense pulsed light treatment of hirsutism: case reports of skin phototypes V and VI

Removal of unwanted hair is a common cosmetic concern. For hirsute women, treatment often requires drug therapy and various methods to physically remove the hair. Traditional methods of hair removal include shaving, waxing, tweezing, depilatory creams and electrolysis. Hair removal methods based on light technology, such as lasers and intense pulsed light systems, are alternative methods for longer-term hair removal. Intense pulsed light has been used in our clinic during the past 2 years to treat light-to-dark skinned patients, including skin types V and VI. We present here the treatment, using an intense pulsed light source, of three dark skinned patients with hirsutism. Patients were treated during multiple sessions (five to seven) for unwanted facial hair. Sessions were conducted monthly and patients were evaluated at follow-up sessions 2–7 months after the final treatment. Successful clearance of unwanted hair was achieved in all three patients with no pigmentary changes observed during the final follow-up sessions. Folliculitis and hyperpigmentation from tweezing were also treated by the intense pulsed light source. These results suggest that intense pulsed light is an effective source for hair removal and may, with proper parameter selection, be useful in the treatment of very dark skin types.     

脉冲激光射线强化金属材料的几个问题

本文讨论了激光脉冲射线强化金属材料的几个问题:强化图形,材料性能,加工用量及表面涂层对被强化表面性能的影响。     

两种方法治疗不同直径直肠癌肝转移的效果和影响生存率的因素分析

目的 探讨超声引导下射频消融术和腹腔镜治疗不同直径直肠癌肝转移的效果和影响生存率的相关因素。方法 回顾性分析2017年1月-2019年12月该院收治的87例行原发癌切除的发生直肠癌肝转移的患者的临床资料,按照不同治疗方法分为两组,观察组（n=45）采用超声引导下射频消融术治疗,对照组（n=42）采用腹腔镜手术切除治疗。比较两组患者疗效、肝功能指标变化情况和患者死亡情况,并对死亡与存活患者进行单因素和多因素分析,研究影响其生存的相关因素。结果 观察组病灶灭活率为81.82%,明显高于对照组的52.38%(P <0.05),观察组大、中、小病灶灭活程度均高于对照组（P <0.05）;两组患者术后血清白蛋白（ALB）、谷丙转氨酶（GPT）、碱性磷酸酶（ALP）和谷草转氨酶（GOT）等肝功能指标水平均高于术前,术后观察组ALB、GPT和GOT水平均低于对照组（P <0.05）;观察组总有效率为86.67%,高于对照组的69.05%(P <0.05);观察组术后2年内死亡率为15.56%,低于对照组的26.19%(P <0.05),两组患者不同直径病灶死亡率比较,差...