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41.
经导管射频消融治疗阵发性室上性心动过速(PSVT)262例,探讨RFCA治疗PSVT的安全性及疗效。方法:房室结双径路改良采用下位法;左侧旁道采用冠状窦电极粗标,大头电极在心室国标。右侧旁道采用左前斜45度。大头电极在心房侧三尖瓣环处细标;房扑时标测心房激动顺序,用隐匿必拖法确定折返环部位,在心房内行线性消融方法治疗。结果:262例中慢-快型房室结折生心动过速(AVNRT)78例。,房室折返性心动 相似文献
42.
CT引导经皮肺穿刺锚状电极高温射频消融治疗肺部肿瘤105例 总被引:31,自引:1,他引:30
目的 观察CT引导经皮肺穿刺高温射频消融治疗105例肺部恶性肿瘤的近期效果。方法 CT引导经皮肺穿刺,可扩展锚状电极配合RF-2000仪高温射频消融治疗原发性肺癌81例,肺部转移瘤24例,共计242个肿瘤,每个肿瘤治疗3~8次,持续时间3~337min。结果 完全缓解(CR)率11.1%,部分缓解(PR)率71.1%,轻微疗效(MR)率13.2%,无改变(NC)率4.5%,其中CR+PR率为82. 相似文献
43.
采用单导管射频消融法治疗12 例预激综合征( W P W) 。12 例中8 例有反复快速性房颤史,3 例须用同步直流电复律,1 例伴有晕厥。旁路分别为左侧8 条,右后间隔2 条,右后侧及右前间隔各1 条,右侧者有1 例并存1 条左侧隐匿旁路。全部旁路一次消融成功。术中未诱发房颤。随访5 ~17 月未见复发。 相似文献
44.
Herbert J. Geschwind Georges Boussignac Jean-Luc Dubois-Randé Robin Zelinsky Seung-Jea Tahk 《Lasers in medical science》1991,6(3):307-310
Laser angioplasty was performed in 66 patients with total occlusion of the ilio-femoral artery. The system used consisted of a pulsed dye laser operating at 480 nm, 50 mJ pulse–1, 2s pulse–1 and 5 Hz. The treatment laser was coupled into a 200m optical fibre wrapped around a coil for improved flexibility and radiopacity. The treatment laser was connected with a diagnostic laser consisting of a continuous wave helium-cadmium laser operating at 325 nm, 50 ms and 3 mW for tissue detection using fluorescence spectroscopy. The primary success rate was 82%, the complication rate was 15% without any clinical sequelae and the 18 month follow-up patency rate was 64%. Due to the narrow pilot channel created by laser angioplasty, in each case a complementary balloon angioplasty was required to restore the arterial lumen. The success rate did not depend upon the length of occlusion but was rather related to the extent of calcification. Laser angioplasty guided by spectroscopy is effective and safe in patients with totally occluded peripheral arteries in whom mechanical devices failed to cross the obstruction. 相似文献
45.
为了探讨局部麻醉和模拟定位机引导在集束巨能刀治疗肺癌的射频治疗的适应证、治疗效果以及并发症的预防和处理,采用0·5%普鲁卡因局部浸润麻醉,模拟定位机引导下经皮穿刺集束巨能刀治疗肺癌46例。CT显示条索状瘢痕残余11例,空洞形成或直径缩小32例,无变化1例,增大2例。治疗中患者均有不同程度的胸腔内热感及短时间内可以忍受的疼痛感。并发症包括气胸7例、皮下气肿5例、发热24例、咯血13例和慢性支气管炎急性发作4例。初步研究结果提示,集束巨能刀射频治疗周围型肺癌疗效满意,尤其适用于直径<3cm的肿瘤。局部麻醉配合全身止痛药物应用可以很好地解决治疗中的疼痛问题,与全麻相比还具有省时省力、费用低的优势;对于周围型肺癌,模拟定位机引导经皮穿刺定位与CT引导相比,同样准确、安全,但操作更为方便。 相似文献
46.
Mataichi Ohkubo Ken Takahashi Masahiko Kishiro Katsumi Akimoto Yuichiro Yamashiro 《Pediatrics international》2004,46(1):39-47
Abstract Background : Use of balloon angioplasty or stent implantation has been reported to be effective in relieving coarctation of the aorta. However, restenosis frequently occurs after balloon angioplasty for native aortic coarctation in small infants, and sometimes develops after stent implantation because of vessel growth. The causes of restenosis remain uncertain. The purpose of this study was to assess the histologic differences in vascular responses to angioplasty using conventional balloon, radiofrequency thermal balloon (RFTB), or stent for experimental aortic coarctation. Methods : The authors surgically created an aortic coarctation model using 14 puppies. Angioplasty using conventional balloon, RFTB, or stent was performed 1 month after the initial operation. At the acute or chronic phase after angioplasty, the animals were killed and histologic studies were performed. Results : More vascular injuries were noted in the specimens from animals undergoing conventional angioplasty than in those with RFTB or stent. However, neointimal hyperplasia was seen more often after RFTB or stent because of the proliferation of smooth muscle cells from the tunica media, caused by secretion of growth factors. Apoptosis reached a peak 1?2 weeks after angioplasty, regardless of the type of intervention. Conclusions : The authors conclude that angioplasty with RFTB or stent can provide relatively small injuries in the vessel wall for aortic coarctation, but care must be taken to prevent restenosis caused by intimal hyperplasia, because neointima hyperplasia is more frequent after RFTB or stent. 相似文献
47.
经导管射频消融术治疗快速性心律失常2 064例结果分析 总被引:2,自引:3,他引:2
目的 通过对射频消融(RFCA)治疗快速性心律失常的结果进行分析,以总结RFCA的治疗经验。方法 对我科开展RFCA治疗快速性心律失常11年的工作进行总结,对2064例患者的治疗结果进行回顾性分析。结果 2064例患者中2008例RFCA治疗成功,成功率达97.3%。并发症发生率为0.73%(15/2064),其中前5年为1.48%(9/609),后6年为0.41%(6/1455);2例安置了永久性心脏起搏器。复发率为1.54%(31/2008),有28例再次行RFCA治疗获得成功。结论 (1)RFCA治疗快速性心律失常安全、有效、成功率高、并发症发生率低。(2)RFCA治疗快速性心律失常的成功率及并发症发生率与术者的操作技术及经验密切相关。 相似文献
48.
半月神经节射频热凝治疗难治性三叉神经痛 总被引:3,自引:1,他引:3
目的探讨半月神经节射频热凝治疗难治性三叉神经痛效果和安全性。方法对三叉神经第Ⅱ支合并第Ⅰ、Ⅲ支或Ⅰ、Ⅱ、Ⅲ支并存疼痛者应用改良的前入路卵圆孔穿刺法行射频热凝毁损术。应用C型臂定位下行卵圆孔穿刺。射频温度控制在75-90℃。结果优良46例,良好1例,总有效率为100%。无严重并发症,随访42例3~18个月,无复发患者。结论在C型臂引导下射频热凝半月神经节毁损术治疗难治性三叉神经痛疗效可靠、定位准确,时患者更安全。 相似文献
49.
目的:测量阵发性心房颤动(atrial fibrillation,AF)患者右心房不同部位的f波振幅,探讨在AF律状态下起搏器心房电极固定位置的选择和植入的可行性。方法:13例阵发性AF患者,窦性心律和AF时,分别把6F的4极电极导管送至高位右心房、中位右心房、低位右心房、房间隔上部、房间隔中部和冠状窦口处。利用Medtronic PSA 5311分析仪测量6F电极1~2极间的电位差。结果:(1)右心房中部和房间隔上部的f波振幅均值分别为(3.93±1.84)mV和(3.96±1.35)mV。(2)右心房中部与高、低位右心房之间的f波振幅均有明显差异(P<0.05);房间隔上部与房间隔中部的f波振幅也有明显差异(P<0.05)。(3)AF时f波振幅均值低于A波振幅均值(P=0.002)。结论:(1)右心房中部和房间隔上部的f波振幅值较其它4个部位的振幅高。(2)AF时f波振幅波动范围明显较大。(3)阵发性AF时,右心房中部与高位、低位右心房之间的电位均有明显差异。右心房中部和房间隔上部的f波振幅较其它部位高,可选为右心房主动固定电极的植入部位。 相似文献
50.
Jianfeng Wang Yaoping Shi Zhibin Bai Yonggang Li Longhua Qiu Guy Johnson 《International journal of hyperthermia》2017,33(2):170-177
Purpose: To determine the feasibility of using radiofrequency hyperthermia (RFH) and to enhance the therapeutic effect of herpes simplex virus-thymidine kinase/ganciclovir (HSV-TK/GCV) for the treatment of hepatocellular carcinoma (HCC).Materials and methods: Human HCC cells (HepG2) were first transfected with lentivirus/luciferase. For both in vitro confirmation and in vivo validation, luciferase-labeled HCC cells and HCC tumour xenografts on mice received different treatments: (i) combination therapy of intratumoral HSV-TK/GCV-mediated gene therapy plus magnetic resonance imaging heating guidewire (MRIHG)-mediated RFH; (ii) gene therapy only; (iii) RFH only; and (iv) phosphate-buffered saline (PBS) as control. Cell proliferation was quantified. Tumour changes were monitored by ultrasound imaging and bioluminescence optical imaging before and at days 7 and 14 after treatments, which were correlated with subsequent histology.Results: In vitro, the lowest cell proliferation was seen in the combination therapy group compared with control groups (29?±?6% vs. 56?±?9%, 93?±?4%, and 100?±?5%, p?.05). Ultrasound imaging of treated animal xenografts showed smaller relative tumour volume in combination therapy group than those in three control groups (0.74?±?0.19 vs. 1.79?±?0.24, 3.14?±?0.49 and 3.22?±?0.52, p?.05). Optical imaging demonstrated significant decrease of bioluminescence signals of tumours in the combination therapy group, compared to those in three control groups (1.2?±?0.1 vs. 1.9?±?0.2% vs. 3.3?±?0.6% vs. 3.5?±?0.4%, p?.05). These imaging findings were correlated well with histologic confirmation.Conclusion: RFH can enhance HSV-TK/GCV-mediated gene therapy of HepG2 cell line and mice human HCC xenografts, which may open new avenues for effective management of HCC using MR/RFH integrated interventional gene therapy. 相似文献