全文获取类型
收费全文 | 44014篇 |
免费 | 3839篇 |
国内免费 | 1184篇 |
专业分类
耳鼻咽喉 | 71篇 |
儿科学 | 870篇 |
妇产科学 | 366篇 |
基础医学 | 3085篇 |
口腔科学 | 223篇 |
临床医学 | 6903篇 |
内科学 | 11911篇 |
皮肤病学 | 661篇 |
神经病学 | 2199篇 |
特种医学 | 1557篇 |
外国民族医学 | 4篇 |
外科学 | 4399篇 |
综合类 | 4606篇 |
现状与发展 | 3篇 |
一般理论 | 1篇 |
预防医学 | 2466篇 |
眼科学 | 240篇 |
药学 | 6910篇 |
86篇 | |
中国医学 | 1241篇 |
肿瘤学 | 1235篇 |
出版年
2024年 | 161篇 |
2023年 | 1218篇 |
2022年 | 1768篇 |
2021年 | 2482篇 |
2020年 | 2640篇 |
2019年 | 2316篇 |
2018年 | 2081篇 |
2017年 | 1778篇 |
2016年 | 1597篇 |
2015年 | 1690篇 |
2014年 | 3006篇 |
2013年 | 3420篇 |
2012年 | 2215篇 |
2011年 | 2485篇 |
2010年 | 1941篇 |
2009年 | 1852篇 |
2008年 | 1825篇 |
2007年 | 1711篇 |
2006年 | 1515篇 |
2005年 | 1322篇 |
2004年 | 1088篇 |
2003年 | 1005篇 |
2002年 | 753篇 |
2001年 | 717篇 |
2000年 | 521篇 |
1999年 | 575篇 |
1998年 | 486篇 |
1997年 | 529篇 |
1996年 | 465篇 |
1995年 | 432篇 |
1994年 | 411篇 |
1993年 | 342篇 |
1992年 | 322篇 |
1991年 | 331篇 |
1990年 | 269篇 |
1989年 | 183篇 |
1988年 | 199篇 |
1987年 | 184篇 |
1986年 | 165篇 |
1985年 | 189篇 |
1984年 | 171篇 |
1983年 | 116篇 |
1982年 | 91篇 |
1981年 | 114篇 |
1980年 | 78篇 |
1979年 | 53篇 |
1978年 | 48篇 |
1977年 | 51篇 |
1976年 | 43篇 |
1975年 | 26篇 |
排序方式: 共有10000条查询结果,搜索用时 9 毫秒
71.
G. R. Q. VEALL 《Anaesthesia》1994,49(5):409-410
72.
73.
L. Marzio F. Di Felice V. Celiberti O. Pieramico L. Grossi M. DiGioacchino B. P. Imbimbo F. Cuccurullo 《European journal of clinical pharmacology》1990,39(4):369-372
Summary To evaluate the influence of the stomach and the cholinergic system on gallbladder contraction induced by physiological stimuli, the reduction in gallbladder volume in 7 healthy volunteers has been studied by real-time ultrasonography after the oral and intraduodenal administration of olive oil, preceded by pretreatment with cimetropium bromide or placebo. After an overnight fast, each subject swallowed 50 ml olive oil or it was administered through a naso-duodenal tube in the proximal duodenum. Cimetropium bromide 5 mg or placebo was given intravenously under double-blind control.After the placebo pretreatment, gallbladder contraction was greater and faster after intraduodenal oil than after oral oil. Cimetropium bromide decreased the extent, velocity and duration of gallbladder contraction induced by intraduodenal olive oil but it only reduced the velocity of the contraction induced by oil given orally.It is concluded that in normal human subjects the stomach modulates the extent and velocity of postprandial gallbladder contraction and that anticholinergic agents antagonize the gastric and duodenal phases of the response of the gallbladder to a meal. 相似文献
74.
75.
J. Boldt H. A. Adams B. Zickmann D. Kling G. Hempelmann 《European journal of clinical pharmacology》1990,38(5):431-436
Summary The release of endogenous catecholamines in aorto-coronary bypass graft patients receiving either 0.5 mg/kg enoximone (n=10), 4.0 mg/kg theophylline (n=10) or saline solution (control,n=10) has been studied, as well as certain haemodynamic parameters. Adrenaline (A) and noradrenaline (NA) concentrations were
not significantly changed by the administration of enoximone. Theophylline caused a small increase in NA (+ 40% in the 1st
min) and a marked increase in A (approximately + 7000% in the 1st min), which still remained elevated at the end of the investigation
period (+ 220% in the 30th min). The major haemodynamic effects of enoximone were a significant increase in cardiac index
(CI; + 35%) and a decrease in pulmonary capillary wedge pressure (PCWP; −27%), pulmonary artery pressure (PAP; −21%), RVEDV
and RVESV, while the heart rate (HR) remained almost unchanged. The dominant haemodynamic effects of theophylline were an
increase in HR (+ 26%; arrhythmia in 3 patients), PAP (+ 22%), and RVEDV (+ 19%), while REVESV (+ 26%), MAP (−16%), CI (−14%),
and RVEF (−15%) fell significantly.
It is concluded that the haemodynamic actions of enoximone are not mediated by catecholamine release, whereas the adverse
cardiovascular effects of theophylline might partly be explained by the significant increase in plasma adrenaline. 相似文献
76.
NAVIN C. NANDA M.D. SAYED MOHAMMED ABD-EL RAHMAN M.D. GAJENDRA KHATRI M.D. GOPAL AGRAWAL M.D. ADEL A. EL-SAYED M.D. HASSAN A. SHEHATA HASSANIAN M.D. MOHAMMAD KAMRAN M.D. JAMES KIRKLIN M.D. DAVID C. McGIFFIN M.D. WILLIAM L. HOLMAN M.D. ALBERT D. PACIFICO M.D. 《Echocardiography (Mount Kisco, N.Y.)》1995,12(6):619-628
In the present study, we compared three-dimensionally (3-D) reconstructed images with multiplane two-dimensional (2-D) transesophageal echocardiographic (TEE) images in 17 patients with various cardiac masses and defects. To overcome the problem of making measurements from 3-D reconstructed images, we carefully "dissected" the 3-D dataset using paraplane and anyplane 2-D sections, which were then used to obtain the maximum sizes of the cardiac masses and defects. Of the 15 vegetations and 9 abscesses detected by 3-D TEE in 7 patients, only 8 (53%) vegetations and 4 (44%) abscesses were detected by multiplane 2-D TEE (P < 0.02). Also, the exact anatomical location, shape, geometry, and extent of various cardiac masses and defects were more clearly delineated by 3-D than 2-D TEE. The maximum dimensions of cardiac masses and defects were larger by 3-D than by 2-D TEE in 17 (89%) of the 19 lesions available for comparison (P < 0.002). In addition, 3-D TEE correlated more closely than 2-D TEE when compared to surgical measurements in three patients in whom they were available. Thus, it would appear that in several instances, the exact size of the cardiac lesion could only be assessed by analysis of the 3-D volumetric dataset. Out preliminary study has demonstrated the superiority of transesophageal 3-D reconstruction over multiplane 2-D TEE in both qualitative and quantitative assessment of various cardiac mass lesions and pathological defects. 相似文献
77.
Kazuhiro Sakata Akio Ohtaki Masaaki Aiba Susumu Ishikawa Yoshimi Otani Yasuo Morishita 《Surgery today》1997,27(1):88-89
We report herein the case of a 77-year-old man with a left ventricular tumor originating from the papillary muscle of the left ventricular wall, in whom a successful tumor resection with mitral valve replacement was performed. The pathological diagnosis of the tumor was confirmed as cardiac fibroma. His postoperative course was uneventful and he is currently well with no signs of recurrence 2 years after surgery. 相似文献
78.
79.
M. Sibille N. Deigat V. Olagnier D. Vital Durand R. Levrat 《European journal of clinical pharmacology》1992,42(4):389-393
Summary All the clinical, laboratory and electrocardiographic adverse events detected during 24 Phase I studies in the same unit over a 5 y period are reported here. 430 healthy male volunteers were involved, corresponding to 5488 days of follow-up.The overall incidence of adverse events was 13.5%, with a significant difference between active drug (15.3%) and placebo (7.4%) treatments. There were 69 distinct types of adverse events. Headache was the most frequent symptom (2%). There were severe adverse events in 20 cases (0.36%), with an incidence of 20/430 per subject (4.6%). There were no deaths or life-threatening events.Although the main objective of Phase I studies is to determine the maximum dose tolerated, cause-effect relationships with adverse events are hard to establish, because of the frequency of adverse events with placebo, and because of the limited number of subjects included such studies. 相似文献
80.
Isoflurane for removal of chest drains after cardiac surgery 总被引:2,自引:0,他引:2
Thirty-five patients who had undergone uncomplicated cardiac surgery were randomly allocated to receive either Entonox or isoflurane 0.25% in Entonox as inhalational analgesia for the removal of their two chest drains. The gases were presented premixed in high-pressure cylinders and were self-administered by means of a demand valve. The removal of the second drain was more painful than the first but that pain was better controlled by isoflurane 0.25% in Entonox than by Entonox alone. 相似文献