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61.
Khema R. Sharma Jane Kent-Braun Mark A. Mynhier Michael W. Weiner Robert G. Miller 《Muscle & nerve》1995,18(12):1403-1411
The goals of this study were to investigate muscle fatigue in patients with multiple sclerosis (MS), and to determine the relationships between muscle fatigue, clinical status, and perceived fatigue. The fatigability of the anterior tibial muscle was quantitated in patients and controls during 9 min of intermittent stimulation (used to eliminate central sources of muscle fatigue). During exercise, the decline in tetanic force, phosphocreatine, and intracellular pH was greater in patients than in controls. The compound muscle action potential amplitude did not decrease during exercise, indicating that there was no failure of neuromuscular transmission during fatigue. Thus, the excessive fatigue in MS developed from sources beyond the muscle membrane. Following exercise, the recovery of tetanic force was delayed in patients (a pattern that suggests abnormal excitation–contraction coupling), whereas the recovery of metabolites was complete in both groups. Muscular fatigue was correlated with clinical disability but not with perceived fatigue. These results suggests that fatigue in MS has both central (perception, upper motor neuron dysfunction) and peripheral (impaired metabolism and excitation–contraction coupling) components.© 1995 John Wiley &Sons, Inc. 相似文献
62.
Juhani Trmnen Osmo Tervonen Antero Koivula Juhani Junila Ilkka Suramo 《Journal of magnetic resonance imaging : JMRI》1996,6(5):805-811
The purpose of this study was to explore systematically the effect of the imaging parameters changeable by the user in spin-echo (SE) imaging sequences to minimize image distortion when imaging joint prostheses. A titanium alloy hip joint prosthesis was studied at 1.0 T. The SE imaging parameters were bandwidth/pixel (BW/p), TE, strength of encoding gradients (matrix size), echo train length (ETL), and direction of phase and frequency encoding. The effect of ETL in rapid acquisition relaxation enhanced (RARE) sequences was also evaluated with a turbo-SE sequence using a different ETL with the same TR and an effective TE. It is concluded that an optimized image quality can be achieved in SE imaging by using a high bandwidth/pixel value (at least 130 Hz/pixel), a high resolution matrix (256–512), sequences with multiple refocusing, and a frequency-encoding axis parallel to the long axis of the prosthesis. The degree of distortion is reduced with this optimized technique. 相似文献
63.
A case of MELAS (mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes) which presented as migraine
complicated by stroke is reported. Strokes associated with migraine have often been reported, but the mechanism remains unclear
and may include a variety of pathologies. MELAS also presents with migrainous headache, vomiting, and stroke-like symptoms.
Magnetic resonance imaging demonstrates characteristic findings. MELAS should be considered in the differential diagnosis
of infarct-like lesions with migrainous headaches in young adults, especially if the symptoms fluctuate and are accompanied
by a homonymous hemianopia.
Received: 23 September 1996 Accepted: 19 February 1997 相似文献
64.
We correlated MRI features with histopathological findings in an HIV-positive patient with vacuolar myelopathy. On MRI symmetrical
nonenhancing high-signal areas in the posterior columns on T2-weighted images result from extensive vacuolation visible on
histological sections.
Received: 18 November 1997 Accepted: 23 March 1997 相似文献
65.
A. Rimmelin P. L. Clouet S. Salatino P. Kehrli D. Maitrot M. Stephan J. L. Dietemann 《Neuroradiology》1997,39(3):203-206
Extradural arachnoid cysts are uncommon expanding lesions in the spinal canal which may communicate with the subarachnoid
space. Usually in the lower thoracic spine, they may cause symptoms by compressing the spinal cord or nerve roots. We report
cases of thoracic and lumbar arachnoid cysts studied by cystography, myelography, CT and MRI. These techniques showed extradural
cystic lesions containing cerebrospinal fluid, with variable communication with the subarachnoid space, causing anterior displacement
and flattening of the spinal cord.
Received: 3 November 1995 Accepted: 16 April 1996 相似文献
66.
Neurosarcoma is a rare tumour originating from the sheath of peripheral nerves. Facial lesions have been reported in about
20 patients. We describe the MRI appearances of neurosarcoma with histological correlation in three patients. The lesions
lay in the submandibular region, the left parapharyngeal space and the right orbit. MRI showed a well-defined mass with mixed
components. The lesions were moderately heterogeneous on T1-weighted images in two cases and on T2-weighted images in all
cases. Gadolinium enhancement occurred in all cases to variable degrees. In two cases, small high signal foci were seen on
T2-weighted sequences. MRI appearances of neurosarcoma are not specific.
Received: 3 September 1996 Accepted: 26 November 1996 相似文献
67.
H. Bonél A. Frick H. Sittek A. Heuck M. Steinborn R. G. H. Baumeister M. Reiser 《Der Radiologe》1997,37(10):785-793
Summary
Purpose of this study was to evaluate the diagnostic value of a low field dedicated MRI system in hand and wrist imaging.
All 308 exams of the hand and wrist, that were performed on a low-field dedicated MRI system (Artoscan, Esaote Biomedica,
Italy) in our institution in 1996, and high-field MRI exams performed in addition as part of the diagnostic work-up, were
evaluated and correlated to final operative (n = 64) and histologic (n = 12) reports. 90 % of all low-field MRI scans stated a diagnosis according to clinical suspicion. In 62 % the clinical question
was answered, and in 26 % additional pathologies were identified. An MR-diagnosis completely different from the clinical suspicion
was stated in 2 %. High field exams contributed additional information in 6 of 36 patients. In 3 patients a tumor was not
shown completely in the limited field-of-view of the dedicated low-field MRI-system. Frequency-selective fat-suppression pulse
sequences and a better spatial resolution were the reasons for the additional information obtained in the other three patients.
Low-field dedicated MR-imaging is a valuable method in the extensive work-up of the hand and wrist. Osseous, ligamentous and
tendinous pathologies are well depicted. Large or infiltrative tumors should be referred to a high-field system.
相似文献
68.
Summary
High-resolution computed tomography (HRCT) provides excellent contrast between osseous structures, air and soft tissue in
conjunction with high spatial resolution. Therefore, thin-section HRCT with bone window setting is the method of choice for
the examination of the middle ear structures. The indications are acute and chronic inflammatory changes, cholesteatoma and
tumor, the “postoperative middle ear”, and malformations. In most cases, HRCT enables differentiation between inflammatory
changes, cholesteatoma, and tumor. The excellent depiction of subtle osseous details enables the identification of erosions
of the ossicles or of the bony walls of the mastoid cells, of osseous defects of the tegmen, of the bony labyrinth, and of
the tympanic course of the facial canal. In addition, HRCT enables excellent depiction of reconstructions of the ossicles
or prosthesis of the ossicles. Although HRCT is the first method of choice, magnetic resonance imaging (MRI) may provide additional
information and lead to a more accurate diagnosis in some cases. This is explained by the excellent soft tissue contrast provided
by MRI. In addition, MRI offers the possibility of using various pulse sequences and the administration of IV contrast material.
Therefore, MRI may allow the differentiation between inflammatory changes, cholesteatoma, and tumor in those cases in which
accurate diagnosis cannot be made by HRCT. The differentiation between a meningocele or meningoencephalocele and other entities
such as tumors or cholesteatoma can be established by MRI. Furthermore, MRI can accurately depict cases of labyrinthitis or
of neuritis of the facial nerve or of intracranial disease caused by middle ear processes, while this is not always possible
by HRCT.
In summary, HRCT of the middle ear is the method of choice, but MRI may provide supplementary information in those cases in
which accurate diagnosis cannot be established by HRCT.
相似文献
69.
Periannan Kuppusamy Penghai Wang Michael Chzhan Jay L. Zweier 《Magnetic resonance in medicine》1997,37(4):479-483
The application of electron paramagnetic resonance imaging (EPRI) to obtain information from biological samples has been limited by the lack of ideal single line radical labels. The commonly used nitroxides exhibit multiple lines causing either hyperfine-based limitations in the maximum obtainable image resolution or hyperfine-based artifacts in the reconstructed image. The use of a novel single-line triarylmethyl paramagnetic label that enables marked enhancement in image quality and resolution is reported. This label exhibits a single line EPR spectrum that is sharp (linewidth ~60 mG in the absence of oxygen) and relatively stable in tissues. The potential of this label in enabling high resolution EPR imaging of biological samples was demonstrated in a series of phantoms and isolated biological organs such as the rat kidney. The images demonstrate that resolutions better than 100 μm could be obtained at L-band on samples of up to 20 mm in size. 相似文献
70.
磁刺激运动诱发电位在腰椎间盘突出所致的腰骶神经根病变中的应用研究 总被引:2,自引:0,他引:2
在35例有L5和/或S1神经根损害表现的腰椎间盘突出患者腰椎区进行磁刺激运动诱发电位(MEP)检查,测定、记录胫前肌、展肌和小趾展肌MEP的起始潜伏期(OL)。结果显示,35例中至少有一条总侧肌肉MEP异常33例(94.3%)。在L4-5椎间盘突出中,以胫前肌的MEP异常为主;在L5-S1椎间盘突出中,以小趾展肌的MEP异常为主。表明腰椎区MEP检查对腰椎间盘突出所致的腰骶神经根病变较为敏感,可为临床诊断提供可靠依据并有助于定位诊断。 相似文献