新形势下我国科技期刊稿源变化趋势——面向作者和科技期刊编辑的问卷调查与分析

【目的】 分析科技评价体系改革和国家大力扶持期刊发展新形势下我国科技期刊稿源动态变化趋势,助力国内科技期刊加速发展。【方法】 针对作者和科技期刊编辑分别设计了“国内科技期刊作者投稿意愿调查”和“2020年国内科技期刊稿源情况调查”问卷,利用问卷星提供的问卷设计和问卷发放(借助科研、期刊交流微信群)、统计分析等功能完成问卷调查。【结果】 大多数(86.2%)期刊2020年的投稿量比2019年增加,但增加1倍以上的期刊仅占6.4%;大部分期刊稿件平均质量有所提高(49.4%)或基本持平(47.0%)。绝大多数作者比较认可中国科技期刊,但同时对期刊发文速度、审稿质量、传播力度等有越来越高的要求,对期刊服务能力、品牌特色有越来越多的期待。【结论】 科技评价体系改革和国家扶持期刊发展为中国科技期刊发展带来了机遇和挑战,面对作者投稿国内期刊意愿的变化,我国科技期刊应该采取更加积极的应对措施,稳步扩大出版量、优化出版流程以承载更多回流的优秀稿件。     

Relationship between unhealthy sleep status and dry eye symptoms in a Japanese population: The JPHC-NEXT study

PurposeTo investigate whether and how unhealthy sleep habits (i.e., the frequency of difficulty falling or staying asleep, and the frequency of waking up tired) and the duration of sleep are related to the prevalence of dry eye disease (DED) in a general population.MethodsThis study included a total of 106,282 subjects aged 40–74 years who participated in a baseline survey of the Japan Public Health Center-based Prospective Study for the Next Generation. DED was defined as the presence of clinically diagnosed DED or severe symptoms. Multivariable-adjusted logistic regression models were used to assess the relationships of various components of sleep status with DED.ResultsHigher frequencies of having difficulty falling or staying asleep, and waking up tired were significantly related to increased DED in both sexes (P_trend<0.001). Compared with those with 8 h/day of sleep, shorter sleepers had an increased prevalence of DED in both sexes, although DED was increased among men who slept ≥10 h/day. By comparing participants with the greatest vs. the least difficulty of falling asleep, the multivariable-adjusted odds ratios (95% confidence interval [CI]) were 2.23 (95% CI, 1.99–2.49) for men and 1.91 (95% CI, 1.76–2.07) for women. When analyzed separately, the magnitude of each relationship was stronger with severe DED symptoms than with clinically diagnosed DED.ConclusionsSleep deprivation and poor sleep quality were significantly related to DED in a Japanese population.     

Thrombotic microangiopathic hemolytic anemia in systemic lupus erythematosus associated with antiphospholipid antibodies: usefulness of monitoring coagulation–fibrinolysis markers

Abstract

We report on a 24-year-old woman with systemic lupus erythematosus and lupus anticoagulant who developed chronic thrombotic microangiopathic hemolytic anemia. The patient responded well to a combination of plasma exchange and anticoagulant therapy. Changes in the molecular markers for coagulation and fibrinolysis corresponded with the disease activity. We suggest that thrombotic microangiopathic hemolytic anemia should be suspected when anemia and thrombocytopenia of unknown etiologies occur in systemic lupus erythematosus. In such cases, the evaluation of molecular markers for coagulation and fibrinolysis might be helpful both for diagnosis and for assessing the response to therapy.     

Reverse engineering techniques applied to a human skull,for CAD 3D reconstruction and physical replication by rapid prototyping

The production of a copy of an existing object of complex shape is one of the typical applications of the integration between two modern computer-based technologies, reverse engineering (RE) and rapid prototyping (RP). The method is extremely versatile and can be used in various applicative domains (e.g. replacement of anatomical parts with artificial prostheses, replication of skeletal remains). Two different acquisition techniques of images of a skull, by laser and by CT scan, were compared to ascertain which enabled more accurate reproduction of the original specimen. The skull was chosen due to it being the body part most often used in medico-legal investigations (for personal identification, skull-photo superimposition techniques, forensic art, etc). Comparison between the copy and the original yielded satisfactory results for both techniques. However, CT scanning demonstrated some advantages over the laser technique, as it provided a cleaner point cloud, enabling shorter pre-reproduction processing times, as well as data on the internal parts, which resulted in the reproduction of a more faithful copy.     

Neonatal education in the North East: A collaborative venture

This article describes a change in the teaching and learning strategy for newly qualified neonatal nurses who wish to become qualified in the speciality (QIS) of neonatal nursing. Two modules have undergone revision in the light of feedback from the Regional Neonatal Network and evaluations from stakeholders. This paper provides the rationale for change and discusses developments in teaching and learning strategies, and the planning and implementing process involved in the change. Factors to take into consideration when evaluating the change and implications for future developments are also briefly discussed.     

“先诊疗后结算”服务模式的实践与思考

"先诊疗后结算"是一种新型的付费方式,可有效节约患者的就诊时间,有助于提高大型医院的医疗服务效率。通过对其具体流程的解读,结合在同济医院的实施及体会,阐明了"先诊疗后结算"的支持环境及应用前景。     

Multi-Center Analysis of Liver Transplantation for Combined Hepatocellular Carcinoma-Cholangiocarcinoma Liver Tumors

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注射用甲磺酸齐拉西酮对双相Ⅰ型障碍躁狂发作急性激越症状的疗效和安全性

目的分析注射用甲磺酸齐拉西酮治疗双相Ⅰ型障碍躁狂发作急性激越症状的疗效和安全性。方法选取2019年4月至2020年4月本院收治的60例双相Ⅰ型障碍躁狂发作急性激越症状患者,按治疗方式的不同分为两组,各30例。对照组采用氟哌啶醇注射液治疗,研究组采用甲磺酸齐拉西酮注射液治疗。比较两组不良反应发生率、阳性与阴性症状量表兴奋因子(PANSS-EC)评分、临床疗效总评量表-病情程度(CGI-SI)评分等。结果治疗后,研究组CGI-SI评分略低于对照组,但差异无统计学意义;治疗前及治疗后2、6、24、48、72 h两组PANSSEC评分比较差异无统计学意义;研究组不良反应总发生率为6.67%,低于对照组的43.33%,差异有统计学意义(P<0.05)。结论与氟哌啶醇注射液比较,临床采用注射用甲磺酸齐拉西酮药物治疗双相Ⅰ型障碍躁狂发作急性激越症状,虽疗效基本相当,但给药安全性更高,对疾病治疗有利。