Genotoxicity studies of glycidol fatty acid ester (glycidol linoleate) and glycidol

Glycidol fatty acid esters (GEs) are found in refined edible oils. Safety concerns have been alleged due to the possible release of glycidol (G), an animal carcinogen.     

Perioperative Nursing and Education: What the IOM Future of Nursing Report Tells Us

Changes in the current health care system have rendered the system unprepared to support new demands. Similarly, nursing education both before and after licensure is no longer adequate. Four of the eight recommendations in the Institute of Medicine’s Future of Nursing report involve changes to nursing education and pose significant goals to achieve. This makes creating innovative ways to meet the demand for educating RNs a necessity. This article discusses the Institute of Medicine’s recommendations, how they relate to perioperative nursing, and ways in which nurses and educators can help promote expectations.     

Design principles for the use of simulation as an aid in interventional cardiology training

Learning complex skills through simulation is a goal for training physicians in specialties such as interventional cardiology, where traditional training puts patients at risk. Intuitively, interactive simulation of anatomy, pathology and therapeutic actions should lead to shortening of the learning curve for novice or inexperienced physicians. An accurate recreation of the interactions among anatomy, pathology and therapeutic actions is a necessary, but not sufficient, condition for the development of a simulation-based training system. In addition to real-time graphic interactivity coupled with haptic response, a successful training tool will require features of a 'learning system' such as: an embedded curriculum, functionality that allows rehearsal and practice, hypertext links to educational information, personal archiving, and instructor review and testing capabilities. We describe how such a system might look for the field of interventional cardiology, and suggest that designing a simulation with both technical and pedagogical fidelity is essential in developing simulation-based training systems in any field of medicine.     

Characteristics of frequent attenders in different age and sex groups in primary health care

Objective. To explore depression from a gender perspective, by capturing depressed women's and men's formulations of their experiences and understanding of their situation. Design. Qualitative interview study. Setting. A healthcare centre in northern Sweden. Subjects. Eighteen patients who had been diagnosed with depression and treated for at least 6 months were interviewed in depth, both women and men of different ages and social status. Open questions were posed around the themes of Malterud's key questions, focusing especially on how the informants conveyed their experiences. Interviewing and qualitative data analysis went on simultaneously. Results. The experience of depression held similarities for men and women, but the outward manifestations differed by gender as well as socioeconomic status. Though experiences of high demands underlay the narratives of all informants, home or work had different priority. Men talked more easily about physical distress – often the heart – than about emotions. Women verbalized more readily emotional distress – shame and guilt – while physical symptoms often revolved around the stomach. Men dealt with insecurity by aggrandizing their previous competence, women by self-effacement. Conclusion. As clinicians we must listen attentively not only to the manifest but to the avoided or unarticulated. By doing so we might counteract normative gender patterns that highlight the depression of women and conceal that of men.     

American Adult Use of Complementary and Alternative Medicine

Editor's Note: In 2004, a study of usage of complementary and alternative medicine among 31,000 American adults revealed that 36% of the population now uses CAM. CAM is defined and usage patterns are described. The survey instrument was developed by the National Center for Complementary and Alternative Medicine and the Center for Disease Control and Prevention National Center for Health Statistics.     

明代地方医学存在的问题及其对策--以吕坤《振举医学》为中心

明中叶以后,随着商品经济的发展,地方医学的弊端逐渐显现,主要有：地方医官地位较低,被地方官员随意差遣;医药经费管理混乱,地方官员挪用药材银两,医官与药商串通骗价问题严重;医生治病不专业,医疗事故频频发生;医学场所荒废不修或变价不存的问题普遍存在。吕坤在《振举医学》中对医政管理、医学教育提出了一系列对策,包括：着力提高医官地位,要求精通医学的人担任医官;严格管理药材银两,保证药材经费的稳定性;强调医术的专与精,鼓励医生熟读医书;对医生的监督和管理更加严格,并将医疗事故纳入司法程序;借助民间社会力量进行医疗救助,使民间力量成为官办地方医学的重要补充。     

Relationship between Ulcerative Colitis and Lung Injuries

Objective To explore the relationship between ulcerative colitis (UC) and lung injuries by assessing their clinical manifestations and characteristics.
Methods From July 2009 to April 2012, 91 UC patients presenting to Longhua Hospital who met the established inclusion and exclusion criteria were enrolled in this retrospective study. According to the scores of disease activity index, the patients were divided into the mild, moderate, and severe groups. Meanwhile, the records of pulmonary symptoms, chest X-ray image, and pulmonary function were reviewed.
Results Sixty-eight (74.7%) patients had at least 1 pulmonary symptom, such as cough (38.5%), shortness of breath (27.5%), and expectoration (17.6%). And 77 (84.6%) had at least 1 ventilation abnormality. Vital capacity value was significantly lower in the severe group than that in the mild group (91.82%±10.38%vs. 98.92%±12.12%, P<0.05).
Conclusions Lung injury is a common extraintestinal complication of UC. According to the theory in Traditional Chinese Medicine that the lung and large intestine are related, both the lungs and large intestine should be treated simultaneously.     

医学知识库领域研究可视化分析

以Web of Science数据库为数据源,利用可视化软件CiteSpace、SATI、Ucinet对医学知识库领域研究文献进行可视化分析,揭示该领域研究力量、核心期刊、核心作者、文献共被引情况、热点等内容。