Barriers to treatment of mental health problems for Palestinian people in refugee camps in Jordan: a cross-sectional study

Background

About 2·1 million Palestinians live in Jordan, and 370?000 Palestinians live in Jordanian refugee camps. Conflict in their country of origin, poverty, unemployment, and squalid camp conditions are some of the environmental factors that render Palestine refugees susceptible to mental health problems. The aim of this study was to identify the barriers that contribute to the treatment gap in mental health-care services for Palestinian refugees in the Baqa'a refugee camp north of Amman, Jordan.

Q-T and JT dispersion in the elderly with urban hypothermia

Twenty elderly patients (12 females and 8 males, aged 65–88 years) were treated because of hypothermia: 11 suffered from moderate (35–32°C) and nine from severe hypothermia (<32°C). The control group consisted of 20 age and sex-matched healthy elderly persons. Twelve-channel electrocardiograms were recorded on admission and during hospitalization. In patients with moderate hypothermia Osborn wave was present in eight of 11, and minimal Osborn wave in three of 11; in severe hypothermia Osborn wave was seen in seven of nine, and minimal in two of nine. The corrected Q-T interval (Q-Tc) was analyzed according to the formula of Bazett: measured Q-T(s)/√R-R(s). The JT and the corrected JT interval (JTc) were measured according to the formula: JT=Q-T−QRS. The Q-T interval index (Q-TI) was measured according to the formula: (Q-TI:656)×(HR+100); and the JT interval index JTI: (JT:518)×(HR+100). The dispersion of the Q-Tc (JTc) was defined as the difference between maximum and minimum measured Q-Tc interval (JTc). The Q-Tc interval in the group with hypothermia was 651.41±130.06 ms, while in the control group it was 398.14±76.21 ms (P<0.001). The Q-Tc dispersion in the group with hypothermia was 91.39±51.98, and in the control group 33.21±10.25 ms (P<0.001). The Q-TcI in the group with hypothermia was 89.91±21.44, and in the control group 39.56±9.41 ms ((P<0.001). The JTc in the group with hypothermia was 542.66±132.74, in the control group: 328.06±76.92 (P<0.001). The JTc dispersion in the group with hypothermia was 79.35±46.22, and in the control group 28.53±7.99 (P<0.0001). The JTcI in the group with hypothermia was 93.06±17.38, in the control group it was 40.23±7.59 (P<0.001). The mean values of the Q-TcI were greater than Q-TI, and the mean values of the JTcI were greater than JTI, but the difference was not significant (P>0.10). The mean values of the JTcI were greater than Q-TcI, but the difference was not significant as well (P>0.05). There was no correlation between rectal temperature and dispersion of Q-T, Q-Tc, JT, JTc, and Osborn wave. The maximum Osborn wave and the maximum Q-T interval were registered in anteroseptal leads (V₂–V₃). The dispersion of the Q-Tc and of the JTc lasted more than Osborn wave. There was no correlation between rectal temperature and PR interval, RR interval and QRS duration. The prolonged dispersion of the Q-Tc (and JTc) last 24–48 h longer than Osborn wave.     

JT8基因在冠状动脉疾病患者的成纤维细胞中表达减低

目的:验证JT8基因在冠状动脉疾病患者的成纤维细胞中表达减低。方法:利用逆转录PCR(RT-PCR)与Northern杂交技术对运用微量材料系列性基因表达(SAGE)技术建立的两个SAGE标签库(JT与WY)的真实性与可靠性进行验证。以管家基因磷酸甘油醛脱氢酶(GAPDH)和肌动蛋白(β-actin)的mRNA表达水平为对照,比较了在JT库中表达水平比在WY库中高8倍的JT8标签对应基因的表达。结果:RT-PCR与Northern杂交的结果与SAGE技术的研究结果一致,SAGE标签JT8对应基因在患者的成纤维细胞中表达减低。结论: SAGE实验的研究方法是可靠的,其实验结果也是可信的,JT8基因在冠状动脉疾病患者的成纤维细胞中表达降低。SAGE实验的研究数据可以为将来进一步寻找新的致病基因提供线索。     

Immunochemical specificity of cytoplasmic inclusions induced by viruses in the potato Y group

Cultured tomato root tips were infected with tobacco mosaic virus (TMV). The synthesis of TMV-RNA and ribosomal RNA was measured in healthy and TMV-infected roots by ³²P labeling and polyacrylamide gel electrophoresis. The region of most active TMV-RNA synthesis was 20–60 mm behind the tip. TMV-RNA was just over 4% of the total nucleic acid present in the entire infected root culture. Incorporation of ³²P into ribosomal RNA was greatly stimulated by TMV infection. This is discussed in relation to the increased size of the ³²P pool in roots infected by TMV: it is concluded that TMV infection stimulates ribosomal RNA synthesis. The region of the infected root showing high stimulation of ribosomal RNA synthesis coincided with the area of high TMV-RNA synthesis.     

射频消融特发性室性心动过速对心室肌复极离散度的影响

目的 研究导管射频消融术（ＲＦＣＡ）对特发性室性惊动国过速速（ＩＶＴ）患者ＱＴ、ＪＴ离散度（ＡＴｄ、ＪＴｄ）的影响。方法 测量１５例ＩＶＴ患者ＲＦＣＡ术前、术后的ＱＴｄ、ＪＴｄ。结果 ＩＶＴ患者ＲＦＣＡ术关、术后ＱＴｄ、ＪＴｄ均无显著性差异（Ｐ〉０．０５）。结论 ＲＦＣＡ不影响ＩＶＴ患者心室肌复极离散度。     

Optimal QT/JT Interval Assessment in Patients with Complete Bundle Branch Block

Background: Prolonged ventricular repolarization duration confers increased risk for malignant ventricular arrhythmias. We sought to clarify the optimal method of QT/JT interval assessment in patients with complete bundle branch block (BBB). Methods: Study patients (n = 71) were dual‐chamber device recipients with baseline left or right BBB who preserved intrinsic ventricular activation during incremental atrial pacing. Patients were classified according to the presence or not of structural heart disease. The former group received chronic amiodarone therapy. QT and JT intervals were recorded at baseline heart rate of 51 ± 4 beats/min and during atrial pacing at 60, 80, and 100 beats/min. We used linear mixed‐effects models to assess the effect of heart rate on the derived QTc and JTc values with the use of six different heart rate correction formulae. Results: Heart rate had a significant effect on the QTc and the JTc intervals regardless of the correction formula used (P < 0.001 for all formulae). The formula of Hodges demonstrated the least variability in QTc and JTc measurements across the different heart rates in both patients groups without (F = 15.05 and F = 13.53, respectively) and with structural heart disease (F = 5.71 and F = 7.69, respectively), followed by the Nomogram and Framingham methods, whereas the uncorrected QT and JT intervals showed comparable heart rate–dependency. The application of Bazett's JTc and QTc led to the most pronounced interval variations in any case with BBB. Conclusions: The Hodges, Nomogram and Framingham correction methods provide best assessment of QT/JT intervals in BBB, whereas Bazett's formula exaggerates heart rate–dependency of ventricular repolarization intervals.     

急性心肌梗塞早期静脉溶栓对QT间期离散度及JT间期离散度的影响

目的 :观察QT间期离散度 (QTd)及JT间期离散度 (JTd)在急性心肌梗塞溶栓治疗前后的变化。方法 :我们将64例施溶栓治疗的急性心肌梗塞 (AMI)病人分为2组 :再通组42例 ,未通组22例。测定和计算溶栓前及溶栓后2、8、24、48小时和1周的同步12导联心电图QTd及JTd并比较它们的变化。结果 :溶栓前再通组与未通组QTd、JTd相比无显著差异 (P>0 05)。溶栓后 ,再通组与未通组各对应时间相比 ,有显著差异 (P<0 01)。结论 :成功的溶栓治疗可使QTd、JTd明显缩短 ,QTd、JTd的变化可作为判断溶栓成功的无创性指标