THE INTERACTION OF RESPONSES IN THE BRAIN TO SEMANTIC STIMULI

Long time-constant EEG recording during paired stimuli has led to the discovery of the contingent negative variation or expectancy wave (Walter, 1964). This effect is produced when a conditional stimulus signals that an imperative stimulus demanding action, decision, or attention will follow at a short, constant time interval. Symbolic and meaningful stimuli were presented to subjects tachistoscopically, and the evoked responses in the brain were electronically averaged. The cerebral evoked responses to such psychological stimuli are more complex than to flashes. A slow negative DC potential shift (CNV) was seen during the interval between an auditory ready signal and the visual exposure if recognition of the stimulus was required, or if it was interesting. Following the visual exposure, a slow positive DC shift occurred. The method has been developed to study the brain responses to psychological stimuli. The amplitude of the responses relates to the information content and subjective factors rather than to the physical strength of the stimulus.     

冲击波致伤作用实验研究进展

原发冲击伤是爆炸产生的冲击波直接作用于生物体而引起的。各种生物激波管和其它冲击波发生装置的研制大大促进了冲击波致伤作用的实验研究的开展。通过将多种动物、离体器官以及培养的细胞暴露于冲击波,获得了大量的原发冲击伤实验研究结果。作者在简述冲击波的基本物理学特征的基础上,着重概括了生物激波管研制和原发冲击伤实验研究方法及其主要进展。     

CD8+T-bet+ cells as a predominant biomarker for inclusion body myositis

Background

Myositis is a heterogeneous group of muscular auto-immune diseases with clinical and pathological criteria that allow the classification of patients into different sub-groups. Inclusion body myositis is the most frequent myositis above fifty years of age. Diagnosing inclusion body myositis requires expertise and is challenging. Little is known concerning the pathogenic mechanisms of this disease in which conventional suppressive-immune therapies are inefficacious.

冲击伤肺肋面的平行出血条纹

本文采用部分肋骨切除术,切除15只家兔双侧5、6、7、8肋中任一肋距脊柱约2cm处一段长约1cm的肋骨。一周后对受冲击波致伤的肺肋面的出血情况进行解剖观察,发现肺肋面的出血条纹呈“工”字形,从而为冲击伤肺肋面的平行出血条纹是肋间压痕这一观点找到了直接的实验证据。     

Asymmetry of Doppler spectrum in stenosis differentiation

The asymmetry of the spectral distribution of ultrasonic Doppler flow velocity signals, assessed using the coefficient of skewness, is discussed as a criterion of stenosis differentiation. Its performance is compared with that of the index of turbulence intensity for both in vitro and in vivo flow Doppler signals, recorded distal to a stenosis. The power spectral distributions are computed using the direct Fourier transform and maximum likelihood method. The asymmetry of spectral distribution has proved to be a more efficient criterion than the turbulence intensity. The maximum likelihood method ensures better stenosis differentiation than the direct FFT method.     

利用脉搏波特征参数连续测量血压的方法研究

通过研究血压与脉搏波特征参数的关系，提出了一个选择多个与血压相关的脉搏波特征参数,通过回归分析建立适合不同人的特征方程，进行血压的连续测量的新方法，为了验证测量结果的准确性；研制了张力计。实验结果表明：该方法具有较高的测量精度，可以应用于临床危重病人的血压监护和一般医学研究中，经过进一步地改进和完善后可应用于载人航天和日常动态环境。     

超短波治疗慢性肺源性心脏病患者的初步探讨

目的:探讨超短波对慢性肺心病CCP患者的临床应用价值。方法:急性发作期CCP患者87例分为超短波治疗组45例和对照组42例,治疗组在常规治疗的基础上给予超短波治疗,对照组行常规治疗。治疗前后分别测定两组患者血浆中血管内皮生长因子VEGF、内皮素(ET-1)含量,动脉血氧分压(PaO2)和平均肺动脉压(mPAP)水平。结果:与对照组比较治疗组治疗后PaO2显著升高(P<0.01),VEGF、ET-1、mPAP明显降低(P<0.01)。VEGF、ET-1与PaO2呈负相关(P<0.01)、与mPAP呈正相关(P<0.01)。结论:超短波可以通过降低肺动脉高压对CCP患者起治疗作用。     

ACE Genotype May Have an Effect on Single versus Multiple Set Preferences in Strength Training

A polymorphic variant of the human angiotensin converting enzyme (ACE) gene was identified. The 'D' (rather than 'I') variant was associated with improvements in strength related to physical training. We set out to determine whether the response to different patterns of strength training might also differ. Ninty-nine Caucasian male non-elite athletes were randomly allocated into one of three groups: 31 non-training/control (CG: 31), single-set (SSG: 35) and multiple-set (MSG: 33). SSG and MSG trained three times a week for 6 weeks. Both training groups were underwent a strength-training program with two mesocycles (12-15 repetition maximum (RM) and 8-12 RM mesocycles). One RM loads in half squat and bench press were assessed before training and after the first and second mesocycles. ACE polymorphisms analysed by polymerase chain reaction (PCR) methods. Subjects with ACE II genotype in the MST group had improved strength development in 12-15 RM, while SST and MST groups had similar gains in 8-12 RM. Subjects with ACE DD genotype in both the SSG and the MSG had similar benefits from both 12-15 RM and 8-12 RM. Strength gains for subjects with ACE ID genotype in the SSG were similar to MSG gains in response to 8-12 RM loads but not with 12-15 RM loads. Additionally, subjects with DD genotype had superior strength gains in both strength training groups. Tailoring strength training programmes (single-set vs. multiple set) according to the athlete's ACE genotype may be advantageous.     

ESWL实际焦点位置的理论和数值分析

从理论和数值模拟两个方面分析了ESWL中的非线性的动力学焦点和实际焦点的位置 ,给出三种典型的动力学焦点的数值结果 ,说明非线性动力学焦点和实际焦点一般不是几何焦点 ,指出正确确定实际焦点在ESWL技术中的重要性。