Hemangiopericytoma/solitary fibrous tumor of the greater omentum: A case report and review of the literature

IntroductionHemangiopericytoma (HPC) has been first described in 1942 by Stout as a tumor originating from the capillary surrounding pericytes. It is known to occur in any anatomical site, especially the extremities and retroperitoneum.Presentation of caseWe describe a case of a 24 year old patient presenting with lower abdominal pain due to a tumor of the greater omentum, the patient was treated by conventional laparotomy with tumor resection and the histological evaluation confirmed the diagnosis Hemangiopericytoma/Solitary fibrous tumor (HPC/SFT). The patient has regularly followed-up with periodic imaging for the last 4 years, with no recurrences.Discussion and conclusionAccording to our knowledge, HPC rarely develops in the greater omentum, only 20 cases were described in the literature. Primary surgical resection is the treatment of choice. There is no benefit of radiation or systemic chemotherapy. Angiogenic inhibitors represent promising systemic therapeutic concepts.     

Cutaneous New World Leishmaniasis on a Port-wine stain birthmark

We present an interesting case report of two sarcoid-like lesions on a port-wine stain (PWS) birthmark in a Brazilian patient which on investigation proved to be cutaneous leishmaniasis.     

Vasculogenesis in infantile hemangioma

Infantile hemangioma is a vascular tumor that occurs in 5–10% of infants of European descent. A defining feature of infantile hemangioma is the dramatic growth and development into a disorganized mass of blood vessels. Subsequently, a slow spontaneous involution begins around 1 year of age and continues for 4–6 years. The growth and involution of infantile hemangioma is very different from other vascular tumors and vascular malformations, which do not regress and can occur at any time during childhood or adult life. Much has been learned from careful study of the tissue morphology and gene expression patterns during the life-cycle of hemangioma. Tissue explants and tumor-derived cell populations have provided further insight to unravel the cellular and molecular basis of infantile hemangioma. A multipotent progenitor cell capable of de novo blood vessel formation has been isolated from infantile hemangioma, which suggests that this common tumor of infancy, long considered to be a model for pathologic angiogenesis, may also represent pathologic vasculogenesis. Whether viewed as angiogenesis or vasculogenesis, infantile hemangioma represents a vascular perturbation during a critical period of post-natal growth, and as such provides a unique opportunity to decipher mechanisms of human vascular development.     

心脏非粘液性原发肿瘤的病理学研究

我院１９６５年至１９９３年间，共检出心脏原发肿瘤２３６例，其中１６例为非粘液性肿瘤，占同期心脏原发肿瘤的６．８％。包括脉管瘤７例，间叶细胞瘤５例，间皮细胞瘤、脂肪瘤、横纹肌肉瘤及纤维弹力瘤各１例。良性和恶性肿瘤各８例。     

Monoethanolamine oleate sclerotherapy for the treatment of intraoral vascular anomalies: retrospective study and suggestion for a clinical guideline

Vascular anomalies are common in the head and neck, and oral lesions are most commonly found on the lips, tongue, mucosa, and palate. Monoethanolamine oleate sclerotherapy (MOS) is an option for treatment, although we know of no established protocols yet. We report the prevalence and characteristics of intraoral vascular anomalies (IVA) and the results achieved with the use of 5% MOS, and suggest a clinical guideline. Data from the medical records of patients with IVA were collected (age, sex, ethnicity, site, size, duration, and treatment). Cases treated with MOS were detailed, and data about number of applications, interval between them, dose, adverse effects, and results were recorded. A total of 65 cases of IVA were found. White-skinned women aged from 61 to 70 years (n = 21) were most likely to be affected, and the lower lip (n = 25) was the most common site. Twenty-seven were treated with MOS using a mean of 1–2 applications with a seven-day interval. The mean dose applied was 0.3 ml/section, which was diluted in local anaesthetic in 38 cases. Twenty-two resolved completely. In summary, we found a prevalence of 4.8% of IVA and European women aged 61 to 70 years were most affected. MOS 5% was effective and safe in the treatment of IVA more than 3 cm in size, with minimal morbidity and adverse effects. We therefore suggest a sclerotherapy protocol of 0.3 ml of the drug (undiluted with anaesthetic) for each 1 cm lesion (maximum 3 cm), with weekly revaluations and further applications when necessary within a 14-day period.     

三维能量多普勒超声诊断婴幼儿浅表血管瘤分期

目的 探讨三维能量多普勒超声鉴别婴幼儿浅表血管瘤增生期与退化期的诊断价值。方法 根据Mulliken分类法与增殖细胞核抗原(Ki-67)表达,将经手术病理诊断为血管瘤的39例患儿分为增生期血管瘤及退化期血管瘤,比较不同分期血管瘤的血管指数(VI)、血流指数(FI)及血管血流指数(VFI)。结果 血管瘤增生期24例,VI 0.51±0.11,FI 38.06±6.64,VFI 19.54±5.52;退化期15例,VI 0.32±0.15,FI 30.81±10.29,VFI 11.07±6.47。增生期VI、FI、VFI均高于退化期,差异均有统计学意义(P均<0.05)。结论 三维能量多普勒超声能实时、清晰、动态显示肿块的血流情况,并对血管瘤分期的鉴别具有重要的临床意义。     

经皮射频毁损治疗肝海绵状血管瘤的临床疗效分析

目的探讨实时超声引导下经皮射频消融治疗肝海绵状血管瘤的临床疗效。方法对19例共22个肝海绵状血管瘤病灶行超声引导下经皮射频消融治疗,分层多点或多次叠合消融治疗55点,平均每例行2.9点。结果 19例患者随访6~96个月,平均随访(44±28)个月。经一次治疗完全缓解(CR)16例,部分缓解(PR)3例,缓解率(CR%+PR%)达100%。病灶直径平均缩小79.8%(80.2%~92.1%),患者平均住院天数8.8天。结论应用实时超声引导下经皮射频消融对肝海绵状血管瘤治疗具有微创、有效、安全等特点,是治疗肝海绵状血管瘤的一种理想方法。     

髌前滑膜血管瘤1例

患者,男,58岁,因右膝关节前侧肿胀7d于2012年4月2日入院。自诉入院前7d于田间长时间蹲位劳作后感觉右膝关节肿痛,未在意,未及时就诊。经休息右膝关节肿胀未见减轻,遂来我院就诊。入院查体:右髌骨前方明显肿胀,可触及一约8cm×6cm×3cm囊性肿物,质软,有波动感,深压痛明显,