广州市海珠区3~12岁儿童身高调查及影响因素分析

目的:了解广州市海珠区儿童身高发育情况,分析其影响因素。方法:随机抽取海珠区904名3~12岁儿童进行体格测量,对家长进行问卷调查,获得儿童身高及其影响因素的相关数据。结果:3~5岁组男、女童,6~岁组男童,7~8岁组男、女童,9~岁组男童的身高均值均低于全国水平(P<0.05)。当前身高低于遗传身高的儿童占21.6%;与遗传身高一致占65%;高于遗传身高的占13.4%。母亲身高,体型是否肥胖,经常吃钙片、喝牛奶,慢性疾病史,每天运动时间为身高的影响因素(P<0.05)。结论:广州市海珠区儿童身高发育的整体水平较低,大部分儿童没有发挥身高的生长潜能,应重视环境因素对身高的影响,采取相应干预措施,促进儿童身高增长。     

广州市居民饮用水选择与亚健康情况调查分析

目的调查广州市居民亚健康及其与广州市居民饮用水选取之间的关系,为有关部门制定相关政策提供参考依据。方法针对调查目的与要求设计调查问卷,问卷内容包括广州市居民亚健康及其各组成因子的调查,也包括个人一般情况、与健康有关的饮用水知识及其知晓情况等。随机抽取广州市10个区的966位居民进行问卷调查,并对有效问卷877份调查数据采用SPSS13.0软件进行统计分析。结果调查发现,与饮水种类选取有关的因素分别为:性别、年龄、学历、职业、收入、居住地、吸烟、饮食习惯、体育锻炼、工作压力、饮食、第三者性生活和熬夜等(P<0.05)。广州市居民饮用水种类的选取不同与亚健康发生率之间具统计学意义(P<0.05),其中选自来水者其亚健康发生率为85.2%,而选活化水者其亚健康发生率为55.6%。在对各饮用水种类分层的亚健康因子分析结果显示,不管选择何种饮用水,感觉疲劳、尤其活动后与用脑后疲劳的亚健康因子评分最高,表明发生亚健康的可能性大。除感觉耳鸣之外,各饮用水种类选取与其他健康因子的亚健康评分之间均有统计学差异(P<0.05),其中选自来水者其各亚健康因子的亚健康评分均比较高,而选活化水者其各亚健康因子的亚健康评分相对较少。结论广州市居民亚健康的发生与饮用水种类的选取有关,选自来水者发生亚健康的可能性较大,而选活化水者其发生亚健康的可能性较小。     

广州地区抗-HCV阳性献血者核酸检测及随访

目的探讨广州地区无偿献血人群HCV感染者自然转归的相关因素。方法对ELSIA法检测为抗-HCV阳性的193名献血者采用荧光定量PCR法检测其HCV RNA,半年后随访并再次做抗-HCV和HCV RNA检测。结果 193名未经治疗的抗-HCV阳性献血者随访前后2次检测的HCV RNA及抗-HCV结果无变化;分别按性别、年龄比较其HCV RNA阳性比例:男性为60.5%(69/114)、女性为34.2%(27/79)(P0.01),35～55岁组为60.9%(42/69)、18～35岁组为43.5%(54/124)(P0.05)。结论女性HCV感染者的自然转归明显好于男性感染者,18～35岁HCV感染者的自然转归优于35～55岁感染者,提示性别及年龄均为HCV感染者自然转归的影响因素。     

1993—2002年广州市学生肺结核防治情况分析

目的　反映广州市学生肺结核病患病特征和防治状况。方法 将1993—2002年广州市结核病专业机构登记的学生肺结核患者,经登记、报告、每年核对及输入电脑统计分析所得。结果 10年间新登记学生肺结核患者1764例,大、中、小学生患者数分别为:777、831和156例。发现方式以因症就诊和健康检查为主,他们多有可疑症状,其中以咳嗽最为常见。多为初治病例(1694例,96.0%),大、中学生多为继发性肺结核(91.2%),而小学生则以原发结核居多(46.8%)。对病例的治疗管理方式有全程督导、住院治疗、全程管理、自服药与强化期督导,其比率分别为38.9%、33.3%、15.6%11.6%0.5%,总治愈率为93.5%。结论 针对大、中、小学生不同群体的特点采取相应的结核病健康促进教育策略,并依据其不同的患病特征采取适当的管治措施。     

Risk of Cardiovascular Mortality Associated With Serum Sodium and Chloride in the General Population

Background

The prognostic value of serum chloride among patients with heart failure was demonstrated by previous studies. However, the association of serum chloride and risk of cardiovascular mortality among the general population remains unclear.

Prevalence of mild cognitive impairment and its subtypes in community-dwelling residents aged 65 years or older in Guangzhou,China

BackgroundPrevalence of mild cognitive impairment (MCI) has been reported substantial variations, and mostly in Western countries. Less is known about MCI in the south of China. The study is to estimate the prevalence of MCI and its subtypes in residents aged 65 year or older in community-dwelling residents of Guangzhou, China.MethodsThe study was a community-based, cross-sectional study conducted in rural and urban areas of Guangzhou between April and October 2009. Eight communities were randomly selected using a cluster sampling method. Each elderly was interviewed with Montreal Cognitive Assessment, the Mini-Mental state examination, Auditory Verbal Learning Test, the Clinical Dementia Rating scale et al. MCI was classified as amnestic MCI (a-MCI) or nonamnestic MCI (na-MCI).Results2427 individuals were contacted, but in-person interviews were conducted with 2111 participants. 299 participants with MCI were identified. The prevalence of MCI, a-MCI and na-MCI was 14.2%, 12.2%, 2.0% respectively. The prevalence of MCI and a-MCI increased with age, decreased with education level, and was higher in rural areas than in urban areas. The difference of prevalence of MCI and a-MCI between women with men wasn't statistically significant(MCIχ2 = 1.0, OR 0.9, 95%CI = 0.6-1.2; a-MCIχ2 = 1.0, OR 0.9, 95%CI = 0.6–1.2), when controlling for education by logistic regression analysis.ConclusionsThe results suggest that 14.2% of elderly individuals are affected by MCI in Guangzhou, China. And MCI was dominated by a-MCI. The prevalence of MCI and a-MCI increased with age, decreased with education level, and was higher in the rural population compared to the urban population.     

Is lymph node dissection necessary for resectable intrahepatic cholangiocarcinoma? A systematic review and meta-analysis

BackgroundThe objective of this meta-analysis was to evaluate the effectiveness and safety of lymph node dissection (LND) in patients with intrahepatic cholangiocarcinoma (ICC).MethodsA literature search with a date range of January 2000 to January 2018 was performed to identify studies comparing lymph node dissection (LND+) with non-lymph node dissection (LND-) for patients with ICC. The LND + group was further divided into positive (LND + N+) and negative (LND + N-) lymph node status groups based on pathological analysis.Results13 studies including 1377 patients were eligible. There were no significant differences in overall survival (OS) (HR 1.13, 95% CI 0.94–1.36; P = 0.20), disease-free survival (DFS) (HR 1.23, 95% CI 0.94–1.60; P = 0.13), or recurrence (OR 1.39, 95% CI 0.90–2.15; P = 0.14) between LND + group and LND-group. Postoperative morbidity was significantly higher in the LND + group (OR 2.67, 95% CI 1.74–4.10; P < 0.001). A subset analysis showed that OS was similar between LND + N- and LND-groups (HR 1.13, 95% CI 0.82–1.56; P = 0.450). However when comparing, OS of the LND-group to the LND+N+ group there was a significant increase in OS for the LND-group (HR 3.26, 95% CI 1.85–5.76; P < 0.001).ConclusionsLND does not seem to positively affect overall survival and is associated with increased post-operative morbidity.     

The clinical value of Fibulin-1 for prognosis and its prospective mechanism in intrahepatic cholangiocarcinoma

Background

Intrahepatic cholangiocarcinoma (ICC) is the second most common malignancy arising from the liver. Fibulin-1 has been demonstrated to be involved in various cancers, however, its role in ICC remains unclear.

广州地区成人血尿视黄醇结合蛋白参考值建立

目的建立广州地区成人空腹静脉血与晨尿视黄醇结合蛋白的参考值范围,促进临床对检验指标的合理应用。方法使用日本日立公司生产的全自动生化分析仪和国产的免疫透射比浊法试剂盒分别检测广州地区600例健康成人空腹静脉血与晨尿中的RBP含量,计算均数±1．96标准差（95％可信限）以建立参考值范围。结果空腹静脉血平均RBP含量15-75岁4个年龄段之间没有显著性差异,但男女之间具有显著性差异：男性为48．5±12．11mg／L,参考值范围为48．5±23．7mg／L;女性为45．0±13．31mg／L,参考值范围为45．0±26．1mg／L;晨尿中RBP平均含量在不同年龄和不同性别之间均无显著性差异,为0．43±0．060mg／L,参考值范围为0．43±0．12mg／L。结论初步得到广州地区健康成人不同性别不同年龄空腹静脉血与晨尿中视黄醇结合蛋白含量概貌,建立了地区性的成人的血尿视黄醇结合蛋白参考值范围。