高度近视LASIK治疗中角膜瓣厚度的探讨

目的:探讨高度近视LASIK治疗中角膜瓣厚度问题。方法:142例(283眼)屈光度-9.00～-12.00 D的近视患者用日本NIDEK MK-2000全自动微型板层角膜切割刀切开角膜瓣,厚度71～184μm,激光切削方式一致。将角膜瓣厚度≤110μm分为Ⅰ组,72例(144眼);角膜瓣厚度>110μm分为Ⅱ组,70例(139眼)。对术前、术后屈光度、视力以 及剩余角膜基质床厚度进行比较。结果:术前平均角膜厚度:Ⅰ组为(531.76±30.28)μm(469～575μm),Ⅱ组为(550.66±24.45)μm(506～584μm),两者有明显差异(P<0.05)。术后剩余角膜基质床厚度:Ⅰ组为(333.01±3.30)μm(273～452μm),Ⅱ组为(309.71±31.41)μm(254～368μm),两者有明显差异(P<0.05)。术前屈光度两组分别为(-10.61±1.01)D及(-10.13±0.73)D,两组间无明显差异(P>0.05),术后7 d时分别为(+1.05±1.38)D及(+1.32±1.70)D,两组间也无明显差异(P>0.05),而术后3m Ⅰ组为(-0.13±0.94)D,Ⅱ组为(-1.06±0.96)D,两组有明显的差异(P<0.01)。术前、术后不论UCVA还是BCVA,两组无明显差异(P>0.05)。结论:治疗高度近视时70～110μm的角膜瓣的制作是合理的,并不影响术后视力,对防止术后屈光回退是有效的,对一个有经验的医生来说是可以很好完成的。     

对耳轮过度前突畸形的整复

对耳轮过度前突为对耳轮的角度过锐，致使耳轮的位置相应后移，表现为与招风耳完全相反的畸形。畸形虽不十分明显，但影响美观。自１９９２年４月开始应用患侧耳廓软骨和耳后皮瓣对５例患者８只外耳进行治疗得到满意效果。认为文中所述方法是矫正对耳轮过度前突畸形的良好方法。     

A new technique for the division of syndactyly

Summary This paper describes a new technique for the division of syndactyly. The commissure is reconstructed by a dorsal trilobed flap and a zig zag incision which produces triangular flaps for the side of the digits. This technique does not require use of a skin graft. Seventeen syndactylies in fourteen children, nine incomplete (six congenital and three secondary to burn) and eight complete syndactylies were treated by this technique. The results after a maximum of twelve months follow-up and the advantages of the technique are discussed.[/ab]     

用氟离子选择电极测定牙膏游离氟

用氟离子选择电极测定牙膏中的氟含量，本法测定回收率为９８．６３％～１０４．００％，变异系数为３．８３％。     

用下睑眼轮匝肌蒂瓣与鼻唇沟皮瓣一次修复下睑全层缺损三例

用下睑眼轮萜肌蒂瓣与鼻唇沟皮瓣一次性修复下睑全层缺损三例。男性１例，女性２例，平均年龄５０岁，均为下睑１／２￣１／３全层缺损。基底细胞癌、睑板腺癌、鳞状细胞癌各１例，皮瓣全部成活。术后随访１年，下睑外形良好，闭眼功能正常。     

The lateral arm free flap in lower extremity reconstruction

Reconstruction of skin defects of the distal third of the leg and foot is often a difficult task. Shape, resistance to shearing stresses in the weight-bearing surface and sensibility are the main features that have to be restored. For coverage of this region, the authors have used, in selected patients, the lateral arm flap (LAF) since 1994. This flap is thin, easy to dissect and has the possibility to be innervated through the posterior cutaneous nerve of the arm. Fourteen cases are presented. The drawbacks of this flap are the loss of sensibility in the forearm (partially transient) and the scar on the arm, which can be rather unsightly in young ladies and when big flaps are harvested skin graft is needed.     

五瓣法整复条蹼状瘢痕挛缩畸形

报告了一组应用五瓣法（５—Ｆｌａｐｔｅｃｈｎｉｑｕｅ）整复损伤和烧伤所致蹼状瘢痕挛缩畸形，获得良好治疗效果。并就手术设计、原理、操作方法及适应证进行了讨论。     

应用胫前肌瓣修复胫骨骨髓炎合并软组织缺损

自1999年1月-2005年3月,应用胫前肌瓣修复胫骨骨髓炎合并软组织缺损13例,同时辅以中药治疗,获得较满意的效果,现报告如下。1临床资料本组13例,男9例,女4例;年龄18~67岁,平均32岁。致伤原因:车祸伤6例,挤压伤4例,烧伤1例,坠落伤2例。胫骨上1/3段1例,中1/3段2例,下1/3段5例,中下2     

The estimation of the plasma free fraction of cyclosporine in rabbits and heart transplant patients: The application of a physiological model of renal clearance

We estimated the free fraction (f_u) of cyclosporine (CyA) in the plasma from concentrations of CyA in urine (C_u) and plasma (C_p), urine flow rate (UF), and glomerular filtration rate in rabbits and in heart transplant patients. Following intravenous administration of CyA (5–30 mg kg^?1) in ten NZW rabbits and oral administration of CyA (4.8–12.1 mg kg^?1) in nine heart transplant patients, CyA concentrations in urine and plasma were measured by HPLC. The ratios of C_u to C_p and UF data were fitted to a physiological model of renal clearance using NONMEM. The free fraction of cyclosporine in the rabbits and the heart transplant patients was 0.0122 and 0.14, respectively. Because of the relatively low permeability of CyA across the tubular epithelium, no apparent equilibrium between C_u and C_p at any urine flow rate was reached and, therefore, the C_u to C_p ratio will not be equal to f_u.