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81.
Objective: To investigate the clinical characteristics and significance of thrombocytopenia after therapeutic hypothermia in severe traumatic brain injury (TBI). Methods:Ninety-six inpatients with severe brain injury were randomized into three groups: SBC (selective brain cooling) group (n=24), MSH (mild systemic hypothermia ) group (n=30), and control (normothermia) group (n=42). The platelet counts and prognosis were retrospectively analyzed. Results: Thrombocytopenia was present in 18 (75%), 23 (77%) and 15 (36%) patients in SBC group, MSH group and control group, respectively (P<0. 01). Thrombocytopenia, in which the minimum platelet count was seen 3 days after hypothermia, showed no significant difference between SBC and MSH group (P>0.05). Most platelet counts (37 cases, 90 %) in hypothermia group were returned to normal level after 1 to 2 days of natural rewarming. The platelet count in SBC group reduced by 16%, 27% and 29% at day 1, 3 and 5 respectively compared with the baseline value. Good recovery ( GOS score 4-5) rate of thrombocytopenia 1 year after injury for hypothermia group (17 cases, 37%) was significantly lower than that of control group (P < 0.01). Conclusions: Therapeutic hypothermia increases the incidence of thrombocytopenia in severe TBI, and patients with thrombocytopenia after therapeutic hypothermia are associated with unfavorable neurological prognosis. 相似文献
82.
贺光照 《重庆医科大学学报》1992,(2)
本文根据34例电击伤临床资料,分析早期处理与病人全身情况、局部损伤愈合以及并发症的关系.并讨论间生态组织的处理原则.结果表明:伤后1天内与伤后3天以上就诊的病人比较,前者全身情况良好,创面感染率低,局部损伤用皮瓣或(和)皮片覆盖效果满意,并发症及截肢率均较低 相似文献
83.
乙型肝炎甲胎蛋白检测与重型肝炎预后指数评估的意义 总被引:1,自引:0,他引:1
给慢性活动肝炎患者输注人胎肝细胞悬液引起血清甲胎蛋白增高反应的初浓度为202±38.3μg/L,其半衰期为1.7天;分布池为6.9一10.2升。重型肝炎生存组血清甲胎蛋白显著高于死亡组,生存组甲胎蛋白与血清总胆红素呈非常显著相关,而死亡组两者无相关性。重型肝炎患者输注胎肝悬液后其血清甲胎蛋白进一步升高者,预后较好。取重型肝炎预后指数0.1为重型肝炎生死的截断点,判断预后的灵敏度、特异度、准确度和阳性预告值分别为79.5%、89.6%、84.8%和87.5%。重型肝炎预后指数的计算可作为判断预后与新疗法疗效的指标。 相似文献
84.
We present an 8 year follow-up on a group of children with refractory epileptic seizures who participated in the early 1980s in a controlled group study on the effects of a broad-spectrum behavior modification treatment program on children with refractory epileptic seizures. In the original study, 18 children were divided into three groups: behavior modification group, attention control group, and control group. The purpose was to investigate the effects of a learning-based treatment program superimposed on a regular medical treatment program. Also, the effects of professional attention were evaluated. At the 10 week and 1 year follow-ups, only the group receiving the behavior modification intervention had a significantly reduced rate of seizure index. The present study investigates these same children 8 years later using the same methods of investigation for an additional 10 week period. The results indicate that a significant reduction in seizures was obtained only for the behavior modification group at the 8 year follow-up. 相似文献
85.
本组老年脑出血发病率57%,明显高于中、青年组脑出血。首要病因是高血压病,社会环境变迁是老年脑出血的重要因素。CT扫描特点为①型别:壳核出血最多(35.4%)、其次为丘脑(29%)、脑叶(21.4%)、其它型别均低于5%;②血肿量:小量出血最多(68.8%)。预后特点是存活率较高87.2%、死亡率仅12.8%。 相似文献
86.
胃癌腹腔脱落细胞检查及临床意义 总被引:1,自引:0,他引:1
腹膜转移是胃癌常见的转移形式。为在肉眼可见转移前发现亚临床的转移现象,自1981年3月至1982年4月,我们共对胃癌病人142例进行了腹腔脱落细胞检查及临床随诊,发现有腹腔脱落细胞阳性者76例(53.5%)。5年随诊结果发现,腹腔脱落细胞阳性者无一例生存>3年;而腹腔脱落细胞阴性的66例中生存5年者有11例。可见,腹腔脱落细胞检查,对胃癌的诊断,治疗和预后判断有一定价值。 相似文献
87.
目的 探讨血尿酸水平对急性心肌梗死(AMI)预后的影响.方法 对198例急性心肌梗死患者的血尿酸水平及其肌酸激酶同工酶(CK-MB)峰值,梗死后心绞痛、心律失常、心源性休克、心力衰竭的发生率和病死率的相关关系进行分析比较.结果 198例中正常血尿酸133例,高血尿酸65例.高血尿酸组CK-MB峰值较高,梗死后心绞痛、心律失常、心力衰竭的发生率和病死率均高于正常血尿酸组(P<0.01或P<0.05).结论 高血尿酸与AMI预后不良有关. 相似文献
88.
目的 探讨血管生成活性在子宫内膜癌发展中的价值。方法 采用Ⅷ因子相关抗原为标志物 ,以免疫组化技术对正常子宫内膜、不典型增生内膜 ,子宫内膜癌组织进行微血管密度 (MVD)测定。结果 ①正常组与内膜癌组比较 (P <0 .0 1) ,正常组与不典型增生组比较 (P <0 .0 5 ) ;从正常内膜、不典型增生到内膜癌组织内MVD逐渐增多 (P <0 .0 5 )。②内膜癌组织内MVD与肿瘤细胞分化程度有关 (P <0 .0 5 )。结论 临床采用MVD测定对子宫内膜增生病变发展和追随检查具有重要价值 ,同时MVD测定可作为判断子宫内膜癌预后的指标之一。 相似文献
89.
本文对85例滤泡性腺癌(FC)、61例滤泡性腺瘤及23例未定性滤泡性肿瘤的临床病理指标进行了多元分析。选出12项良恶鉴别的指标,建立了logistic判别方程,判别符合率100%。141例获随访结果,其中116例随访达10年以上。随防结果分析显示FC微小浸润型和明显浸润型自下而上率差异显著,11项临床病理指标对FC有预后意义。 相似文献
90.
B. H. Green J. R. M. Copeland M. E. Dewey V. Sharma I. A. Davidson 《International journal of geriatric psychiatry》1994,9(10):789-795
The Liverpool Continuing Health in the Community Study has followed up 1070 elderly community subjects over 6 years. In the first year 123 subjects had case-level depression. Three years later 49 (39.8%) of the previously depressed were recovered, 33 (26.8%) were depressed, 16 (13%) were not available for interview and 25 (20.3%) were dead. This study looks at factors associated with the 3-year outcome of patients who were depressed at year 0. Two outcome groups that were compared were a recovered depression group and a recurrent/persistent depression group. The factors that were significantly associated with a recurrence of depression (or persistent depression) at year 3 were bereavement of a close figure in the 6 months before interview, loneliness and life dissatisfaction at year 3. A variety of traditional risk factors for depression (including age, marital status, physical ill-health and incapacity) failed to attain significance in predicting recurrent or persistent depression. When combined, both recovered and recurrently depressed groups at year 3 had significantly higher levels of pain and a higher number of serious upsets in the past 6 months and 6 weeks compared to a compared to a control group. The depressed at year 0 were more likely to have entered more dependent forms of accommodation by year 3. 相似文献